Clinical trials: Chest Wall Disorder
Chronic Obstructive Pulmonary Disease, Chronic Cough
Study of AffloVest in At-Risk Respiratory Patients During COVID-19 Pandemic
The purpose of the study is to investigate the addition of high frequency chest wall oscillation (HFCWO) therapy to the prescribed care regimen to support the diaphragm during airway clearance among post-COVID patients with COPD…
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Cough, Covid19
- Trial name
- NCT04654481
- Testing
- HCFWO, Standard Care Plus Monitoring
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Breast Cancer
Immediate Implant Breast Reconstruction
The purpose of this study is to study the impact of the immediate implant breast reconstruction for patients with mastectomy and postoperative chest wall radiotherapy
- Trial name
- ISIS (NCT02055937)
- Testing
- immediate implant breast reconstruction
- Where
- France
- Volunteers
- 53 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Breast Cancer
Multicenter Phase II Study of Apatinib in Patients With Advanced Breast Cancer(CABC006)
The treatment of the patients with recurrent and metastatic breast cancer remains a major problem. There is still a lack of effective targeted therapy for Her-2 negative breast cancer.Based on the present researches on the…
- Trial name
- NCT02878057
- Testing
- Apatinib
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Respiratory Failure, Neuromuscular Disease
Autotitrating Versus Standard Non-invasive Ventilation (NIV) in Acute Exacerbation of Respiratory Failure
The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients admitted to hospital with acute exacerbation of chronic respiratory failure.
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01174316
- Testing
- AutoVPAP™, VPAPIIIST-A™
- Where
- United Kingdom
- Sponsor
- ResMed
Chest Wall Deformity, Funnel Chest
Chest Wall Deformities in Children - Epidemiological Data
Pectus excavatum (PE) or funnel breast is the most common congenital deformity of the chest wall, which occurs in about 1 in 400 births with a boy to girl ratio of 4: 1 to 3: 1.
- Trial name
- NCT04448574
- Testing
- Chest Wall Deformities Questionaire
- Where
- 2 sites in Germany
- Volunteers
- 96 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pulmonary Neoplasm
Trial of Pre-operative Chemoradiotherapy Followed by Surgical Resection in Pancoast Tumors (JCOG 9806)
The purpose of this study is to evaluate the safety and efficacy of the trimodality (concurrent chemoradiotherapy followed by surgical resection) approach in superior sulcus tumors.
- Trial name
- NCT00128037
- Testing
- mitomycin C, vindesine, cisplatin and radiotherapy
- Where
- Japan
- Volunteers
- 75 people
- Sponsor
- Japan Clinical Oncology Group
Esophageal Cancer, Esophagectomy
Oesophagectomy and Chest Wall and Respiratory Function
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%).
- Conditions
- Esophageal Cancer, Esophagectomy, Respiratory Function Loss
- Trial name
- NCT03835273
- Testing
- 3D motion capture system, Incentive spirometry, Questionnaires
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Lung Cancer
Efficacy Study of a Selective Chest Wall Restriction Belt in Postoperative of Lung Resection
The objective of this study is to evaluate the efficacy of a new medical device in post-surgery of lung resection. The principle of this new device is based on selective chest wall restriction.
- Trial name
- CTS-POP (NCT04369118)
- Testing
- Conventional follow-up, Conventional follow-up+chest wall restriction belt
- Where
- 3 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Grenoble
Chronic Ventilator Dependency
HFCWO in Prolonged Mechanical Ventilation Patients
The effectiveness, safety and tolerance/comfort of high-frequency chest wall oscillation (HFCWO) in prolonged mechanical ventilation patients remain unknown.
- Trial name
- NCT02077738
- Testing
- HFCWO (Hill-Rom Vest™ Airway Clearance System)
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Taichung Veterans General Hospital
Bronchiectasis
Clinical Effectiveness Of High Frequency Chest Wall Oscillation (HFCWO) In A Bronchiectasis Population
The primary objective is to compare the patient's baseline QoL prior to HFCWO use against the patient's QoL at various study timepoints over a one-year period of HFCWO use.
- Trial name
- HFCWO (NCT04271969)
- Testing
- SmartVest Airway Clearance System
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Electromed, Inc.
Perfusion Pressures, Central Venous Pressure
Sternal Wall Pressure in the Cath Lab
This protocol is a prospective interventional pilot study at the Children's Hospital of Philadelphia to determine whether or not two increments of sternal pressure known to occur during "leaning" in CPR affects hemodynamic…
- Conditions
- Perfusion Pressures, Central Venous Pressure, Cardiac Output, CPR
- Trial name
- NCT01117883
- Testing
- Application of two different sternal weights
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Philadelphia
Respiratory Function Impaired
Efficacy of Osteopathic Manipulation on Breathing Mechanics in a Healthy Population: A Randomized Controlled Study
This study focused on improving breathing mechanics by using various osteopathic manipulative therapy (OMT) techniques. The investigators randomly assigned participants to a control group who received sham treatment and a…
- Trial name
- NCT04975542
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Jayla Bostic
Non Small Cell Lung Cancer
Pre-Operative Assessment of Chest Wall Invasion in NSCLC Using Pre-Operative, Surgeon Performed Ultrasound
Non-Small Cell Lung Cancer (75% of lung cancer) is associated with involvement of the parietal pleura and or chest wall (soft tissue and/or bone) in 5-8% of patients.
- Trial name
- CT0010 (NCT01206894)
- Testing
- Transthoracic Ultrasound
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain, Postoperative, Cardiac Surgery
Chest Wall Block After Sternotomy: Randomized Controlled Trial in Cardiac Surgery: (PABLOS Study)
The main objective is to compare the effectiveness of LocoRegional Anesthesia (LRA) (bilateral transverse thoracic block or bilateral parasternal block) in addition to standard management compared to standard management alone…
- Trial name
- PABLOS (NCT05345639)
- Testing
- LRA Loco-regional anesthesia, Standardized post-operative analgesia protocol
- Where
- France
- Volunteers
- 254 people
- Sponsor
- University Hospital, Angers
Lung Cancer, Metastatic Cancer
Combined Deep Inspiration Breath Hold (DIBH)-Expiration Planning Technique in Patients With Lung Tumors in Close Proximity to the Chest Wall
The purpose of this study is to evaluate a new radiation planning and treatment delivery technique called Deep Inspiration Breath Hold (DIBH) and expiration technique.
- Trial name
- NCT04507828
- Testing
- Treatment Planning using the DIBH Technique
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Indiana University
Amyloidosis, Basal Cell Carcinoma
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
This phase II trial studies whether providing cancer treatment in the home is preferred over the traditional clinic setting and if it improves treatment satisfaction in cancer patients living in the Florida Panhandle and…
- Conditions
- Amyloidosis, Basal Cell Carcinoma, Biliary Tract Carcinoma, Bladder Carcinoma
- Trial name
- NCT07285044
- Testing
- Cancer Therapeutic Procedure, Questionnaire Administration
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Deformity of Chest Wall
SPAIN Chest Wall Deformity Project (Pectus Repair)
Context: Chest wall deformities in children are relatively common. One such deformity, known as Pectus Excavatum (PE), involves a concavity of the chest and is the most frequent of these abnormalities - present in approximately 1…
- Trial name
- NCT02098681
- Where
- United States
- Volunteers
- 348 people
- Sponsor
- Boston Children's Hospital
Stroke
Acute Effects After Stretching Respiratory Muscles on Ventilatory Pattern and Volume Distribution of Chest Wall
The purpose of study is to evaluate the acute effects of respiratory muscles stretching on ventilator pattern and volume distribution of chest wall in patients with right hemiparesis post-stroke and our hypothesis is that the use…
- Trial name
- NCT02416349
- Testing
- Respiratory Muscles Stretching, Control Group
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Universidade Federal de Pernambuco
Breast Cancer
Reirradiation With Concurrent Paclitaxel for Breast Cancer
The purpose of this trial in addition to a dose finding study for concurrent Paclitaxel, will be to establish a treatment algorithm for chest wall reirradiation.
- Trial name
- NCT02058667
- Testing
- Paclitaxel+Initial Radiation+Boost
- Where
- United States
- Sponsor
- University of Kentucky
Breast Cancer, Male Breast Cancer
Vorinostat and Trastuzumab in Treating Patients With Metastatic or Locally Recurrent Breast Cancer
This phase I/II trial is studying the side effects and best dose of vorinostat when given together with trastuzumab and to see how well they work in treating patients with metastatic breast canceror breast cancer that has…
- Conditions
- Breast Cancer, Male Breast Cancer, Recurrent Breast Cancer, Stage IIIB Breast Cancer
- Trial name
- NCT00258349
- Testing
- vorinostat, trastuzumab
- Where
- 25 sites in United States
- Volunteers
- 16 people
- Sponsor
- National Cancer Institute (NCI)