Clinical trials: Child Malnutrition
Malnutrition
Effectiveness Comparison of Three Supplementary Foods in the Treatment of Moderate Acute Malnutrition
The purpose of this study is to compare the recovery rates of moderately malnourished Malawian children treated with either milk-enriched corn/soy blend, soy/peanut fortified spread or a commercially produced ready-to-use therapy…
- Trial name
- NCT00998517
- Testing
- Soy/peanut fortified spread, Milk fortified corn/soy blend, Supplementary Plumpy®
- Where
- Malawi
- Volunteers
- 2,712 people
- Sponsor
- Washington University School of Medicine
Obese, Vitamin D Deficiency
Roles of Vitamin D and HDL in Obese Children
This is a pilot study to determine the association between Vitamin D deficiency in obese children and low high density lipoprotein (HDL) and dysfunctional HDL.
- Conditions
- Obese, Vitamin D Deficiency, Low HDL
- Trial name
- NCT02135913
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Xiang-An Li
ARFID, Picky Eating
Chompions! A Treatment Study for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
Avoidant Restrictive Food Intake Disorder (ARFID) is a disorder that affects toddlers, children, adolescents, and adults. Individuals with ARFID are not able to consume an adequate amount or variety of food to a degree that it…
- Conditions
- ARFID, Picky Eating, Eating Disorders in Children
- Trial name
- NCT05105308
- Testing
- Family Assisted Diet (FAD), Feeling and Body Investigator_ARFID Division (FBI-ARFID)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Malnutrition
Prevention of Linear Growth Failure in Infants and Young Children With Lipid-based Nutrient Supplements (iLiNS-DOSE)
The use of lipid-based nutrients (LNS), such as Nutributter or fortified spread (FS), have been associated with improved growth and development outcomes among infants in Ghana and Malawi.
- Trial name
- iLiNS-DOSE (NCT00945698)
- Testing
- Lipid-based nutrient supplement, 10gM, Lipid-based nutrient supplement, 20gM, Lipid-based Nutrient Supplement, 20gNoM
- Where
- Malawi
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- Tampere University
Environmental Enteric Dysfunction, Stunting
Maternal Probiotic Intervention to Improve Gut Health
There is an urgent need to identify interventions that can improve the supportive uterine environment in which the fetus establishes his/her growth.
- Trial name
- MPIGH (NCT05922683)
- Testing
- Vivomixx, CapScan®
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Aga Khan University
Asthma, Vitamin D Deficiency
Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial
This is a pilot randomized controlled trial of lower vs. higher dose vitamin D supplementation in D-deficient asthmatic children, to determine necessary sample sizes for outcome measures in a larger multisite study, and to…
- Trial name
- D-Asthma (NCT02054975)
- Testing
- Vitamin D2 + vitamin D3, Vitamin D3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nationwide Children's Hospital
Vitamin D Deficiency, 25-Hydroxyvitamin D3 Deficiency, Selective
Vitamin D3-enhanced Eggs in Preschool Children
This is double-blind, controlled fiel trial, to compare fortified egg with D3-or 25(OH)D3 and non-fortified eggs in healthy preschool-age children 12 to 60 months of age, affiliated to day-care centers at Secretaria de Desarrollo…
- Trial name
- VD3-egg (NCT06096194)
- Testing
- vitamin D-enhanced egg, Control
- Where
- Mexico
- Volunteers
- 275 people
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Malnutrition
Mesalamine in Environmental Enteropathy
Undernutrition is one of the most important health issues in Kenya. Children who are chronically undernourished do not reach their full potential and are at increased risk of infectious disease.
- Trial name
- NCT01841099
- Testing
- Mesalamine
- Where
- Kenya
- Volunteers
- 44 people
- Sponsor
- Kelsey Jones
Hypovitaminosis D
Vitamin D Versus Placebo in the Treatment of Vague Musculoskeletal Pain in Children
Other studies suggest that low Vitamin D levels may contribute to musculoskeletal pain. Hypothesis: Administration of oral Vitamin D supplements will improve vague musculoskeletal pain in children.
- Trial name
- NCT00944606
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Stunting, Anemia
Effectiveness Study During the First 1,000 Days in Kenya
Malnutrition is a public health problem in Kenya, with 26% of children underfive years of age stunted, and 26% of pre-school children, 26% of women of reproductive age and 42% of pregnant women being anaemic, respectively.
- Conditions
- Stunting, Anemia, Micronutrient Deficiency
- Trial name
- NCT03558464
- Testing
- Intervention (integrated package), Control
- Where
- Kenya
- Volunteers
- 1,199 people, healthy volunteers welcome
- Sponsor
- Fabian Rohner
Schistosomiasis in Children, Soil Transmitted Helminth (STH) Infections
Burden of Schistosomiasis and Soil-transmitted Helminth Infections in Schoolchildren in Banfora, Burkina Faso
A cross-sectional study will be conducted among 300 schoolchildren in the Banfora region, including 120 in urban and 180 in rural areas, to assess the prevalence of schistosomiasis and soil-transmitted helminth infections.
- Conditions
- Schistosomiasis in Children, Soil Transmitted Helminth (STH) Infections, Malaria Infection, Anaemia
- Trial name
- NTDs_SAC (NCT06973200)
- Testing
- Dihydroartemisin-piperaquine
- Where
- Burkina Faso
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre MURAZ/Institut National de Santé Publique
Nutritional Rickets
Vitamin D and Genetics in Nutritional Rickets
The purpose of this study is: 1. To compare the response of rickets to calcium with and without vitamin D. 2. To assess whether vitamin D increases calcium absorption in calcium deficiency rickets. 3.
- Trial name
- NCT00949832
- Testing
- Vitamin D + Calcium, Calcium, Vitamin D2
- Where
- Nigeria
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Malnutrition
Non Randomized Controlled Intervention Study Comparing Two Interventions of Nutritional Supplement on Malnutrition, Health and Mortality
The hypothesis for the study is that 12 months of a Ready-To-Use Supplementary Food (RUSF) distributions have a greater impact on children's health than the standard RUSF distributions during the hunger gap period (june to…
- Trial name
- NRCI-ASPE (NCT02085044)
- Testing
- Ready-to-Used Supplement Food administration
- Where
- Chad
- Volunteers
- 5,700 people, healthy volunteers welcome
- Sponsor
- France Broillet
Diarrhea, Wasting
Lactoferrin and Lysozyme Supplementation for Long-term Diarrhea Sequelae
Children in low- and middle-income countries who are hospitalized for diarrhea and also have malnutrition are at high risk for illness and death in the 6 months period following treatment for diarrhoea despite receiving current…
- Conditions
- Diarrhea, Wasting, Malnutrition, Child
- Trial name
- NCT05519254
- Testing
- Lactoferrin, Lysozyme, Lactoferrin + Lysozyme
- Where
- 4 sites in Kenya
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Phase 3 Safety and Efficacy Study of CTAP101 Extended-release Capsules in Children With Secondary Hyperparathyroidism
This is a phase 3, multi-center, randomized, double-blind, placebo-controlled study in children with stage 3-4 chronic kidney disease (CKD), secondary hyperparathyroidism (SHPT) and vitamin D insufficiency.
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Vitamin d Deficiency, Secondary Hyperparathyroidism
- Trial name
- NCT05543928
- Testing
- CTAP101
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- OPKO Health, Inc.
Fetal Alcohol Syndrome, HIV
Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)
The purpose of this study is to test a mother-to-mother intervention during pregnancy and after delivery with mothers in South Africa, most of whom are at risk delivering babies with fetal alcohol syndrome, babies that are…
- Conditions
- Fetal Alcohol Syndrome, HIV, Nutrition Disorders
- Trial name
- NCT00996528
- Testing
- Philani Intervention Program
- Where
- South Africa
- Volunteers
- 1,239 people
- Sponsor
- University of California, Los Angeles
Infant Malnutrition, Cognitive Change
Integrating Infant Feeding Counselling With Psychosocial Stimulation to Improve Child Growth and Development in Urban Slum of Bangladesh
Undernutrition and poor cognitive development affect many children under 5 in developing countries, who are exposed to multiple risk factors including poverty, malnutrition, poor health, and unstimulating home environments.
- Trial name
- NCT03040375
- Testing
- Peer counselling
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hypophosphatasia
Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)
This Clinical Trial is being conducted to study Hypophosphatasia (HPP), a bone disorder caused by gene mutations or changes. These gene mutations cause low levels of an enzyme needed to harden bone.
- Trial name
- NCT00894075
- Testing
- ENB-0040
- Sponsor
- Alexion Pharmaceuticals, Inc.
Severe Acute Malnutrition
RECIPE BASED F100 INTERVENTION FOR NUTRITIONAL EFFICACY IN SAM (REFINE-SAM )
This open-label randomized controlled trial evaluates the efficacy and safety of multiple formulations of the F-100 therapeutic feed during the rehabilitation phase among children aged 6-59 months with SAM, in comparison to…
- Trial name
- REFINE-SAM (NCT07130877)
- Testing
- WHO F100, WHO RECIPE BASED F100
- Where
- 2 sites in Pakistan
- Volunteers
- 114 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan