Clinical trials: Childhood Asthma
Asthma, Asthma in Children
Effectiveness of a Mobile Health Intervention in Improving the Technique of Inhaled Medications Among Children With Asthma
In this trial, the investigators aim to determine if a new mobile health intervention (BreatheSuite) can increase inhaler technique and adherence amongst participants aged 10-18.
- Trial name
- NCT03615248
- Testing
- BreatheSuite
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Memorial University of Newfoundland
Asthma in Children, Obesity
Mechanistic Study of Inspiratory Training in Childhood Asthma (MICA)
This is single-center cross-sectional mechanistic study in lean and obese children with moderate-severe asthma, followed by a randomized, SHAM-controlled trial of Inspiratory Training (IT).
- Conditions
- Asthma in Children, Obesity, Pediatric Obesity, Pediatric Asthma
- Trial name
- MICA (NCT05945355)
- Testing
- Pro2 - Low Dose - 40% of participant's MIP, Pro2 - High Dose - 75% of participant's MIP
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Duke University
Asthma, Recurrent Cough
Spirometry and Methacholine Challenge Test in Asthmatic Children Age 3-6years
Rational: The possible contribution of methacholine challenge test via spirometry to the clinical diagnosis of young children with various respiratory symptoms, the most appropriate spirometry index, and the proper cutoff point…
- Trial name
- MCH-preschool (NCT00550758)
- Testing
- Methachoine, spirometry
- Volunteers
- 84 people
- Sponsor
- Rambam Health Care Campus
Asthma
Pediatric ASTHMA-Educator
This project seeks to develop and pilot test the pediatric ASTHMA-Educator mobile application.
- Trial name
- NCT03520881
- Testing
- Pediatric ASTHMA-Educator mobile application
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Montefiore Medical Center
Acute Otitis Media (AOM), Strep Pharyngitis
Evaluation of the Medentum Diagnostik Platform for Pediatric ENT Conditions and Asthma
This study evaluates the diagnostic performance, usability, and clinical utility of the Medentum Diagnostik platform, a multisensor device with integrated software and artificial intelligence, in pediatric patients with asthma…
- Conditions
- Acute Otitis Media (AOM), Strep Pharyngitis, Asthma Exacerbation, Pediatric Asthma
- Trial name
- NCT07500532
- Testing
- Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of AOM and strep pharyngitis, Diagnostik home-based platform: multisensor device, software application, and artificial-intelligence algorithms that predict diagnosis of wheeze/asthma exacerbation, Routine Asthma Management (in-person and telehealth visits)- Control Group
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Medentum Innovations
Asthma in Children
The Effect of 10-Week Exercise Training on Children With Asthma
The goal of this research is to determine whether 10-weeks of exercise training can benefit asthmatic children and young adults with a history of exercise-induced bronchoconstriction (EIB).
- Trial name
- NCT03716219
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Asthma in Children
Leo Study Unstable Asthma
This is a prospective, observational study to investigate the agreement of the Leo device signal derivation with gold standard asthmatic testing in recently exacerbated asthmatic children.
- Trial name
- NCT05308277
- Testing
- Leo device monitoring
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- ResMed
Asthma
Intermittent and Daily Dosing for Episodic (Periodic) Asthma (0476-302)(COMPLETED)
This is a year-long study evaluating the efficacy of both daily and intermittent treatment of asthma in children who experience symptoms episodically (i.e., seasonally, usually in the context of upper respiratory tract infection).
- Trial name
- NCT00337675
- Testing
- montelukast sodium
- Volunteers
- 1,771 people
- Sponsor
- Organon and Co
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Asthma
Childhood Asthma Research and Education (CARE) Network Trial - Best Add-On Therapy Giving Effective Response (BADGER)
Asthma is a common, serious illness among children in the United States. While a low dose of inhaled corticosteroids (ICS) may effectively control symptoms, some children may require additional medications to maintain adequate…
- Trial name
- BADGER (NCT00395304)
- Testing
- fluticasone propionate + montelukast, fluticasone propionate, fluticasone propionate + salmeterol
- Where
- 5 sites in United States
- Volunteers
- 182 people
- Sponsor
- Milton S. Hershey Medical Center
Asthma, Asthma in Children
Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care
Caregiver-child dyads will be recruited during child's hospital admission for asthma exacerbation. Recruitment sites will be mainly Children's National Hospital Sheikh Zayed campus, as well as regional partners: Holy Cross…
- Trial name
- H2H (NCT05991115)
- Testing
- Hospital to Home Transition (H2H)
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Kavita Parikh
Asthma Attack, Asthma in Children
The Effect of Nebulization Positions in Asthmatic Children
The purpose of this study was to establish the effect on pulse rate, oxygen saturation, respiratory rate, pain and anxiety levels of Fowler's and the forward-leaning positions during nebulization in children experiencing asthma…
- Conditions
- Asthma Attack, Asthma in Children, Asthma Acute, Asthma
- Trial name
- NCT05318885
- Testing
- A Randomized Controlled Study
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University - Cerrahpasa
Asthma in Children, Status Asthmaticus
BPAP in Pediatric Asthma Pilot Study
The investigators aim to study the effect and safety of bilevel positive airway pressure (BPAP) in children with moderate to severe asthma exacerbations - by examining the effects of early initiation of BPAP in pediatric patients…
- Trial name
- NCT04656587
- Testing
- Philips Respironics V60 Non-invasive ventilator, BPAP, Standard Therapy
- Sponsor
- Columbia University
Asthma in Children
Oral Health Status of Asthmatic Children
This study aimed to investigate the dental caries experience, periodontal health and salivary properties of asthmatic and non-asthmatic children ⁄ adolescents.
- Trial name
- NCT04388098
- Testing
- Diagnosis of caries experience and periodontal health
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Trakya University
Asthma
Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464)
Prolongation of the EPAAC™ trial - NCT00152464 (The Early Prevention of Asthma in Atopic Children). 36 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in young atopic…
- Trial name
- NCT00160563
- Testing
- LEVOCETIRIZINE
- Where
- 51 sites in Australia, Belgium and 8 more
- Volunteers
- 207 people
- Sponsor
- UCB Pharma
Asthma, Vitamin D Deficiency
Vitamin D in Pediatric Asthma: a Randomized Controlled Open-label Pilot Trial
This is a pilot randomized controlled trial of lower vs. higher dose vitamin D supplementation in D-deficient asthmatic children, to determine necessary sample sizes for outcome measures in a larger multisite study, and to…
- Trial name
- D-Asthma (NCT02054975)
- Testing
- Vitamin D2 + vitamin D3, Vitamin D3
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nationwide Children's Hospital
Asthma
Cost-effectiveness Study of Beclomethasone Versus Ciclesonide as Controller Medications in Pediatric Asthma
The Objective was to Develop a Cost-Effectiveness study that compares Ciclesonide and Beclomethasone in pediatric asthma control.
- Trial name
- NCT01333800
- Testing
- Beclomethasone, Ciclesonide
- Where
- Colombia
- Volunteers
- 94 people
- Sponsor
- Grünenthal Colombiana S.A.
Bronchial Asthma
Some Biomarkers in Bronchial Asthma in Children
Asthma, a disease characterized by chronic airway inflammation and hyper -responsiveness, is a common disease that affects all age groups. Asthma may be manifested as irreversible airflow obstruction in some patients.
- Trial name
- NCT04175093
- Testing
- asymmetric dimethylarginine
- Volunteers
- 105 people
- Sponsor
- Assiut University
Asthma, Lung Diseases
Pediatric Asthma Controller Trial (PACT)
To evaluate current and novel therapies and management strategies for children with asthma. The emphasis is on clinical trials that help identify optimal therapy for children with different asthma phenotypes, genotypes, and…
- Trial name
- NCT00272506
- Testing
- inhaled corticosteroid, long-acting beta2-agonist
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma, Allergic Sensitization
Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) Study
The purpose of this study is to determine whether early childhood exposure to common allergens (substances that can trigger allergies and asthma) can prevent the development of asthma in children at high risk for developing the…
- Trial name
- GPAC (NCT00346398)
- Testing
- Oral mucosal immunoprophylaxis (OMIP)
- Where
- 3 sites in United States, Australia
- Volunteers
- 51 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)