Clinical trials: Childhood Asthma
Healthy
Preventive Medicine Study of Childhood Atopic Diseases
Under environmental intervention programs, to explore the associations between Environmental Tobacco Smoke (ETS) and changes of pulmonary function, cytokines and new-onset asthma between different groups.
- Trial name
- NCT00960596
- Testing
- Health promotion and health education for smoking habits
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Asthma in Children
Dynamic Respiratory Muscle Strength and Endurance in Childhood Asthma
Peak inspiratory flow (PIF) may be due to respiratory muscle strength, especially in those with severe airflow obstruction. PIF appears to be lower in children and adolescents with asthma than in non-asthmatics and correlates…
- Trial name
- NCT06053905
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Asthma
Better Pediatric Asthma Outcomes Through Chronic Care
This 3-year, multi-site study focuses on the translation of cost-effective methods to bring a chronic care model to the care of poor, minority, inner-city children with asthma, at risk of the worst outcomes for the leading…
- Trial name
- NCT00355069
- Testing
- electronic (computer based) provider feedback tool
- Where
- United States
- Volunteers
- 548 people
- Sponsor
- UConn Health
Asthma (Diagnosis)
Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma
Acute asthma exacerbation is caused by dysregulated pulmonary inflammatory pathways such that standard treatment includes prompt administration of exogenous systemic corticosteroids (SCs), but there remains an ongoing dialogue…
- Trial name
- PATCH (NCT07455396)
- Testing
- Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Johns Hopkins All Children's Hospital
Asthma
Comparison of Vibrating Mesh Nebulizer Versus Jet Nebulizer in the Pediatric Asthma Patient
The purpose of this study is to compare clinical outcomes related to the current practice of using a jet nebulizer (JN) with aerosol mask (AM) or mouthpiece (MP) versus a vibrating mesh nebulizer (VMN) with a valved-mask (VM) or…
- Trial name
- NCT02774941
- Testing
- Jet Nebulizer, Vibrating Mesh Nebulizer
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Prevention of Asthma With Levocetirizine (36 Month Treatment) in Young Children Suffering From Eczema (Atopic Dermatitis) and Sensitized to Grass Pollen and House Dust Mite and Having Completed the Previous EPAAC Trial (NCT00152464)
Prolongation of the EPAAC™ trial - NCT00152464 (The Early Prevention of Asthma in Atopic Children). 36 months study to evaluate the efficacy and safety of levocetirizine (LCTZ) in preventing the onset of asthma in young atopic…
- Trial name
- NCT00160563
- Testing
- LEVOCETIRIZINE
- Where
- 51 sites in Australia, Belgium and 8 more
- Volunteers
- 207 people
- Sponsor
- UCB Pharma
Breathing Techniques, Asthma Control Level
Effects of Buteyko Breathing Exercise in Children With Uncontrolled Asthma
This randomized controlled trial study aimed to measure the effectiveness of the combination of 4-weeks Buteyko breathing exercises and pharmacological therapy compared with pharmacological therapy alone in children with…
- Conditions
- Breathing Techniques, Asthma Control Level, Asthma in Children, Asthma Patients
- Trial name
- NCT07025616
- Testing
- Buteyko, Asthma reliever and controller
- Where
- Indonesia
- Volunteers
- 74 people
- Sponsor
- Ivan Sofian Wibowo
Lung Diseases, Asthma
Nutrition in Pregnancy, Birth Weight, and Childhood Asthma
To evaluate the role of maternal diet and birth weight in the etiology of childhood asthma and other allergic disorders.
- Trial name
- NCT00006404
- Sponsor
- Harvard Pilgrim Health Care
Asthma in Children
Improving Asthma Care Together (IMPACT): A Shared Management Pilot Study
This study aims to iteratively develop, refine and test the Improving Asthma Care Together (IMPACT) Intervention for school-age children (7-11 years) with persistent asthma and their parents.
- Trial name
- IMPACT (NCT04908384)
- Testing
- Improving Asthma Care Together (IMPACT)
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Washington
Immunity, Respiratory Infection
Childhood Infection and Immunity Longitudinal Cohort
This prospective observational study will enroll approximately 1,200 children from birth through 7 years of age in Zhejiang Province, China.
- Conditions
- Immunity, Respiratory Infection, Asthma
- Trial name
- NCT07815925
- Where
- 2 sites in China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Asthma in Children
An Asthma Collaboration to Reduce Childhood Asthma Disparities on the Navajo Nation
National Jewish Health and The University of Arizona worked with Navajo Nation organizations to develop this program to improve the health of children with asthma. The Navajo Community Asthma Program will have two main parts.
- Trial name
- NCT03377647
- Testing
- Asthma Care Provider Training, School Staff Asthma Education
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Jewish Health
Asthma in Children
Telemedicine Enhanced Asthma Management - Uniting Providers
This research study is an innovative school-based program for urban children with moderate to severe persistent or difficult-to-control asthma.
- Trial name
- TEAM-UP (NCT03545906)
- Testing
- TEAM-UP Intervention Group, Enhanced Care Comparison
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- University of Rochester
Asthma
Prospective Study of Dietary Factors, BMI, and Risk of Asthma in Children
Asthma is a common illness among children in the United States. While there are many known causes of asthma, including tobacco smoke, pollen, dust, or other allergens, the exact cause of asthma in some individuals remains…
- Trial name
- NCT00454415
- Where
- United States
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma, Asthma in Children
AeviceMD for Pediatric Asthma Management
A wearable remote patient monitor (AeviceMD) is to be used to monitor the respiratory health of pediatric asthma patients in this pilot study.
- Conditions
- Asthma, Asthma in Children, Pediatric Asthma, Chronic Respiratory Disease
- Trial name
- APAM (NCT06321471)
- Testing
- AeviceMD
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Irina Dralyuk
Asthma in Children
Adjustment of Asthma Treatment in Children Based on an Indirect Hyperresponsiveness Test
The aim of the study is to assess the usefulness of the indirect bronchial hyperresponsiveness test (with hypertonic NaCl) in determining the optimal dose of inhaled steroids to maintain asthma control.
- Trial name
- NCT04509921
- Testing
- asthma treatment adjustment taking account on degree of bronchial hyperresponsiveness
- Where
- Poland
- Volunteers
- 108 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Asthma
Effects of Montelukast in Children With Asthma
Leukotriene receptor antagonists (LTRAs) reduce fractional exhaled nitric oxide (FENO) concentrations in children with asthma, but the effect of LTRA withdrawal on FENO and lung function is unknown.
- Trial name
- NCT00675285
- Testing
- montelukast sodium
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Catholic University of the Sacred Heart
Asthma in Children
Impact of Modified Specific Carbohydrate Diet on Bronchial Asthma Control in Children
The aim of this study will explore if the specific carbohydrate diet has an effect on asthma control in children and if it will affect the frequency, severity, and duration of asthma and thus provide it as a potential…
- Trial name
- NCT05728385
- Testing
- Modified Specific carbohydrate diet for 3 months
- Volunteers
- 60 people
- Sponsor
- Tanta University
Asthma in Children
Chicago Asthma School-Directed Child-Centered Assessment and Dissemination of Evidence
Research has shown that adherence to evidence-based asthma guidelines leads to improved outcomes, yet critical gaps remain in the implementation of these guidelines, particularly among minority and low-income youth.
- Trial name
- CASCADE (NCT06320210)
- Testing
- Multicomponent program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Asthma in Children
Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)
The long-term goal is to implement an evidence-based asthma intervention based on the Center for Disease Control's recommended framework (EXHALE) within Baltimore City Public Schools (BCPS).
- Trial name
- NCT05814510
- Testing
- Asthma CHAMPS full program, Asthma CHAMPS Wait List Control
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Childhood Asthma
Smartphone-facilitated Asthma Control
The objective of this protocol is to pilot an innovative approach to medication adherence to determine if such an approach will improve inhaled corticosteroid (ICS) medication adherence, a critical gap in improving the health of…
- Trial name
- SNAPP (NCT02205723)
- Testing
- Asthma teaching in ER, Smartphone Asthma Control
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center