Clinical trials: Childhood Asthma With Acute Exacerbation
Childhood Asthma With Acute Exacerbation
Azithromycin Treatment of Hospitalized Children With Asthmatic Symptoms
The purpose of this double-blind, randomized, controlled clinical trial is to investigate the effect of a three-day azithromycin treatment versus placebo treatment in children aged 1-5 years who are hospitalized due to…
- Trial name
- COPSACazt (NCT05028153)
- Testing
- Azithromycin Oral Liquid Product
- Where
- Denmark
- Volunteers
- 320 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Childhood Asthma With Status Asthmaticus
Status Asthmaticus on the PICU; Intravenous Salbutamol
Although IV salbutamol is frequently used in children in a wide range, pharmacodynamic data are scarce. To date, there is an insufficient evidence base to guide initial and subsequent dosing recommendation for its IV use in…
- Trial name
- STATIC IV (NCT03493503)
- Testing
- Salbutamol, Sodium Chloride 0.9%
- Where
- Netherlands
- Volunteers
- 58 people
- Sponsor
- Erasmus Medical Center
Asthma Exacerbation
Study of Preventive Treatment With Symbicort or Budicort Turbohaler in Childhood Asthma Return to School Epidemic
During the second week of September( week 38 of the year)there are recorded data of exacerbation of asthma all over the world, including Israel.
- Trial name
- NCT01179152
- Testing
- Budesonide turbuhaler, Budesonide+Formoterol turbuhaler
- Where
- Israel
- Volunteers
- 225 people
- Sponsor
- Meir Medical Center
Childhood Asthma, Asthma Control
Pollution Intervention to Impact Kids Asthma Study
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children.
- Conditions
- Childhood Asthma, Asthma Control, Asthma Exacerbation, Air Pollution, Risk Reduction Behaviors
- Trial name
- PIKAS (NCT07261423)
- Testing
- EPA-AQI, Commerical-AQI, Education and plan
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- University of Pittsburgh
Asthma Exacerbation, Children
A Comparative Study of Adding Ipratropium to Salbutamol for the Treatment of Asthma Attack in Children
The goal of this clinical trial was to determine if adding ipratropium bromide to salbutamol improves asthma treatment in children.
- Trial name
- NCT06918418
- Testing
- Salbutamol (Ventolin®), salbutamol + ipratropium bromide nebules
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Acute Exacerbation of Asthma
Dexamethasone Versus Prednisolone in Acute Exacerbation of Childhood Asthma
Because of insufficient local comparative data, this study was designed to determine the outcome of intravenous dexamethasone in contrast to oral prednisolone in acute exacerbation of asthmatic children.
- Trial name
- NCT07275593
- Testing
- Dexamethasone, Prednisolone
- Where
- Pakistan
- Volunteers
- 224 people
- Sponsor
- Muhammad Aamir Latif
Childhood Asthma
Smartphone-facilitated Asthma Control
The objective of this protocol is to pilot an innovative approach to medication adherence to determine if such an approach will improve inhaled corticosteroid (ICS) medication adherence, a critical gap in improving the health of…
- Trial name
- SNAPP (NCT02205723)
- Testing
- Asthma teaching in ER, Smartphone Asthma Control
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Asthma Acute, Asthma in Children
Non-invasive Ventilation vs. Standard Therapy for Children Hospitalized With an Acute Exacerbation of Asthma
Acute asthma produces greatly increased work of breathing and increased oxygen requirement secondary to bronchial narrowing and airway obstruction by inflammatory secretions.
- Trial name
- NCT03296579
- Testing
- BiPAP, CPAP, Ipratropium
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Common Cold, Pharyngitis
Supporting Parents to Choose Wisely
The goal of this multi-method study including a randomized control trial and qualitative interviews is to see how useful blogshots (an image that summarizes information) are at helping parents increase their knowledge and manage…
- Conditions
- Common Cold, Pharyngitis, Acute Otitis Media, Acute Asthma
- Trial name
- NCT06005337
- Testing
- Blogshots 1-3, Blogshots 4-6
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Asthma
To Evaluate the Efficacy of Supplementation With L. Reuteri + Vit. D3 in Asthmatic Children
The purpose of this project is to evaluate in a randomized clinical trial, double-blind, controlled, the effects of a dietary supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 in reducing bronchial inflammation…
- Trial name
- NCT02734446
- Testing
- Reuterin D3 drops
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- University of Campania Luigi Vanvitelli
Childhood Asthma With Acute Exacerbation
Antibiotic Treatment of Recurrent Episodes of Asthma in Children
Copsac has discovered that asthmatic exacerbations are as closely linked to bacterial as to viral infection. The current study will examine whether treatment of asthmatic exacerbations with macrolide antibiotics - in the abscence…
- Trial name
- AB-studie (NCT01233297)
- Testing
- Azithromycin
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen Studies on Asthma in Childhood
Childhood Asthma With Acute Exacerbation
Comparison of Nebulizers vs Metered-Dose Inhalers With Spacer Device For Treatment Of Childhood Wheeze
The goal of this randomized controlled trial is to compare two different devices for the administration of the standard protocol drug.
- Trial name
- NCT06201156
- Testing
- Metered Dose Inhaler With Spacer Device
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- Khyber Teaching Hospital
Asthma Acute, Asthma Childhood
ASMact: Study on Management of Bronchial Asthma
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
- Conditions
- Asthma Acute, Asthma Childhood, Asthma in Children, Asthma Crisis
- Trial name
- NCT07412769
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Meyer Children's Hospital IRCCS
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma Exacerbation
The purpose of this study is to evaluate the effectiveness of nebulized magnesium sulfate as a vehicle for albuterol in children with moderate to severe asthma exacerbation.
- Trial name
- NCT01515995
- Testing
- Nebulized magnesium sulfate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma Attack
Phenotyping and Classifying Asthma Exacerbations
An observational study in patients between 12 and 70 years old with an acute asthma exacerbation, to determine the relation between phenotypical characteristics and the treatment response.
- Trial name
- ExCluSieF (NCT05304039)
- Testing
- Questionnaires, Spirometry, Fractional Exhaled Nitric Oxide (FeNO)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Franciscus Gasthuis
Asthma Childhood, Asthma Attack
Remote Monitoring of Asthma in Children and Young People
The objective of this study is to determine whether healthcare data and remotely collected patient data can accurately predict asthma attacks in children and young people aged 5-17 years.
- Conditions
- Asthma Childhood, Asthma Attack, Remote Monitoring, Risk Assessment
- Trial name
- NCT07129616
- Where
- United Kingdom
- Volunteers
- 900 people
- Sponsor
- University of Edinburgh
Asthma, Asthma in Children
AQI and Childhood Asthma: an Intervention
This is a small pilot prospective intervention trial in children with asthma who will be randomized to receive either (A) Air Quality Index (AQI) education + an asthma action plan (control) or (B) AQI education + an asthma action…
- Trial name
- NCT04454125
- Testing
- AQI intervention, Routine care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Pittsburgh
Upper Respiratory Tract Infection, Asthma
Reducing the Acute Care Burden of Childhood Asthma on Health Services in British Columbia
The purpose of this study is to investigate the benefits of giving filled prescription of a medication to be used upon early onset of symptoms of URTI induced asthma.
- Trial name
- NCT01326494
- Testing
- Arm 1 Oral Cortico Steroids
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of British Columbia