Clinical trials: Childhood Autism
Autism Disorder
TRIal of PPF3 vs. PlaCEbo in the TReatment of Children and AdolescenTs With NeurOdeveloPmental DisorderS
A Randomized Placebo-Controlled TRIal of PPF3 vs. PlaCEbo in the TReatment of children and AdolescenTs with NeurOdeveloPmental DisorderS
- Trial name
- TRICERATOPS (NCT07893964)
- Testing
- PPF3
- Where
- 4 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autistic Disorder
Comparison of Applied Behavioral Analysis (ABA) Versus ABA and Risperidone
Hypotheses: 1. Preschool children with autism spectrum disorders (ASDs) who undergo ABA treatment only will demonstrate significantly better outcomes compared to an age and severity matched control group without ABA treatment. 2.
- Trial name
- NCT00374764
- Testing
- Risperidone, ABA
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Autism Spectrum Disorder, High-functioning Autism
Effects of Transcranial Pulse Stimulation on ASD
The aim of this study is to evaluate the efficacy and tolerability of TPS on young adolescents with ASD. Methods: This is a two-armed, randomized, double-blinded, sham-controlled trial.
- Trial name
- NCT05408793
- Testing
- Transcranial Pulse Stimulation
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Autism, Autism Spectrum Disorder
Familial Fecal Microbiota Transplant for the Treatment of Subjects With Autism Spectrum Disorders
This is an open-label clinical trial to evaluate the benefits of familial fecal microbiota transplant following a 6-week treatment with Vancomycin in adult subjects with ASD for treatment of social deficits and language delays.
- Trial name
- NCT04630847
- Testing
- Fecal Microbiota Transplant
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- ProgenaBiome
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Brain Response to Serotonergic Medications in ASD
This study investigates brain response to single acute dose of citalopram, tianeptine, and placebo in males with and without autism spectrum disorder.
- Trial name
- NCT04145076
- Testing
- Citalopram, Tianeptine
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
Autism, Autism Spectrum Disorder
Improving Academic and Social Functioning in Middle-Schoolers With Autism
The goal of this study is to test how well two group interventions work for middle-school children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT06705907
- Testing
- Achieving Independence and Mastery in School (AIMS), Building Essential Social Skills for Teens (BESST)
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
Autism Spectrum Disorder, Language Disorders
Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium
The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves language as well as the…
- Trial name
- NCT04060017
- Testing
- Levoleucovorin Calcium
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Southwest Autism Research & Resource Center
Insomnia
Parent-Mediated Telehealth Intervention for Insomnia in Young Autistic Children
This study will evaluate the efficacy of a structured parent-mediated behavioral intervention called Sleep Parent Treatment (SPT) for insomnia in autistic children ages 3 to 7 years 11 months, compared to another behavioral…
- Trial name
- NCT07435740
- Testing
- Sleep Parent Training (SPT), Sleep Parent Education (SPE)
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- The Cleveland Clinic
Autistic Disorder of Childhood Onset With Full Syndrome
Impact of Sports Activity on Pragmatic Skills of Children
To investigate the effects of structured physical exercises/outdoor sports on social interaction/communication skills of children with Autism in Pakistan.
- Trial name
- NCT04593576
- Testing
- Physical activity protocol/out door sports, Intensive table teaching speech therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Autism Spectrum Disorders, Brain Disease
A Study of the Association Between Autism and Immune Changes in the Brain
Background: People with autism and autism spectrum disorders have problems with communication, behavior, and socializing, and many also have intellectual and developmental disabilities.
- Conditions
- Autism Spectrum Disorders, Brain Disease, Autism, Healthy Volunteers
- Trial name
- NCT01322555
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
A Study of Balovaptan in Adults With Autism Spectrum Disorder With a 2-Year Open-Label Extension
This study will evaluate the efficacy, safety, and pharmacokinetics of 10 mg of oral administration balovaptan once a day (QD) compared with matching placebo in adults (18 years and older) with autism spectrum disorder (ASD).
- Trial name
- NCT03504917
- Testing
- Balovaptan
- Where
- 51 sites in United States, Canada and 4 more
- Volunteers
- 322 people
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder
Family Centered Occupational Therapy on Play Skills and Participation of Children With ASD
Play skills and participation of children with Autism Spectrum Disorder (ASD) have been restricted by their core symptoms, resulting in heightened parenting stress and affected family daily life.
- Trial name
- NCT02795611
- Testing
- Family-centered occupational therapy, regular occupational therapy, intervention done outside our hospital
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Transcranial Magnetic Stimulation (TMS) to Treat Depression in Autism Spectrum Disorder
This study will assess clinical and behavioral measures along with electroencephalogram (EEG), event-related potentials (ERPS), and eye-tracking (ET) prior to and following a single intermittent Theta Burst Stimulation (iTBS)…
- Trial name
- NCT06142955
- Testing
- MAGSTIM Rapid2 TMS system
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorder
Tele-rehabilitation Program: An Innovative and Sustainable Early Intervention Service for Children With Autism Spectrum Disorders
In Singapore, Autism Spectrum Disorders (ASD) is ranked number one in disease burden for children 0-14 years of age. The Child Development Unit at the National University Hospital serves 3000 children annually, of which 25-30% of…
- Trial name
- NCT05792449
- Testing
- Foundational Skills Curriculum, Foundational Skills Curriculum - Telerehabilitation
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- National University Hospital, Singapore
Autism Spectrum Disorder
Screening for Autism Spectrum Disorders Using Auditory Brainstem Responses
The purpose of this study is to develop an Auditory Brainstem Response (ABR) based neurological screening method to detect increased risk for Autism Spectrum Disorders (ASD) and other neurological conditions in newborns.
- Trial name
- NCT03971578
- Testing
- No Intervention Provided
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Intelligent Hearing Systems
Autism Spectrum Disorder
Effectiveness of Caregiver-involved Group-based NDBIs Intervention for Autistic Preschoolers
This is a study that investigate the feasibility, acceptability, and preliminary efficacy of NDBIs for autistic preschoolers delivered in a group-setting.
- Trial name
- NCT06221943
- Testing
- Group-based Naturalistic Developmental Behavioral Intervention, One-on-one Naturalistic Developmental Behavioral Intervention, ASD Diagnosis
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Autism, Autism Spectrum Disorder
Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach
New research suggests that about 1 in 8 children may be diagnosed with an autism spectrum disorder (ASD) in the United States. This could be due to several reasons which remain unknown.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related
- Trial name
- NCT05453708
- Testing
- Survey
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Walden University
Motor Skills Disorders, Autism Spectrum Disorder
DCD & ASD Imaging Intervention Study
Developmental Coordination Disorder (DCD) is a neurodevelopmental disorder that affects a child's ability to learn motor skills, such as tying shoelaces, learning to print, or riding a bicycle (APA 2013).
- Trial name
- NCT04119492
- Testing
- CO-OP Treatment Group
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
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