Clinical trials: Childhood Depression
Childhood Anxiety Disorder, Childhood Depression
Brief Internet-delivered Intervention for Children and Adolescents With Anxiety and Depression Symptoms
Investigators developed a brief standardized internet-delivered cognitive-behavioral program for treating anxious and depressive symptoms in children and adolescents in the context of COVID-19 pandemics in Brazil.
- Trial name
- NCT05139433
- Testing
- Telepsychotherapy, Psychoeducational Videos
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- University of Sao Paulo
Lupus Erythematosus, Systemic, Depression
Engagement in CHildhood-Onset Systemic Lupus
The goal of this observational (Aim 1) and pilot study (Aim 2) is to better understand how depression symptoms may contribute to how well adolescent and young adults with lupus follow-up with their lupus clinical care.
- Trial name
- ECHOS (NCT05693571)
- Testing
- Valera Smart Phone Application and Care Manager Dashboard
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Montefiore Medical Center
Major Depressive Disorder, Childhood Trauma
RESET-psychotherapy: the Effectiveness of Trauma-focused Therapy in Patients With Depression and Childhood Trauma
Depression is a debilitating psychiatric disorder with a recurrent and progressive course. Around 25% of depressive patients has experienced moderate to severe levels of childhood trauma (CT), resulting in earlier onset and more…
- Trial name
- NCT05149352
- Testing
- Treatment as usual (TAU) for depression, Trauma-focused therapy (TFT)
- Where
- 3 sites in Netherlands
- Volunteers
- 158 people
- Sponsor
- Amsterdam UMC, location VUmc
Mother to Child Transmission, Breast Feeding
Trauma-informed Obstetric Care for Perinatal Health: a Pilot Study
The study will test trauma-informed obstetric care training and supervision for obstetric clinicians in relation to prenatal mental health and attachment formation (early predictors of child development) in women presenting for…
- Conditions
- Mother to Child Transmission, Breast Feeding, Trauma
- Trial name
- NCT07195058
- Testing
- Trauma Informed Obstetric Care (TIOC)
- Where
- Argentina
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depression in Adolescence, Adverse Childhood Experiences
Life Experiences in Adolescents and the Development of Skills
The primary objective of this study is to assess acquisition and retention of a Cognitive Behavioral Therapy (CBT)-based "cognitive restructuring" skill, among young adolescents (12-15 years of age) with elevated depression…
- Trial name
- LEADS (NCT04719897)
- Testing
- FIRST: Repairing Thoughts
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Pittsburgh
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Childhood Asthma, Childhood Anxiety Disorder
COPE for Children With Asthma: Intervention for Children With Asthma
Children with a chronic condition are at a significantly higher risk for anxiety and depression than those without a chronic condition. Asthma is the most common childhood chronic condition.
- Conditions
- Childhood Asthma, Childhood Anxiety Disorder, Childhood Depression
- Trial name
- NCT03481673
- Testing
- COPE for Asthma
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Hunger, Child Development
Building Wealth and Health Network: A Microfinance/TANF Demonstration Project
The goals of the The Building Wealth and Health Network (The Network) are to develop and rigorously test an asset building model that will build financial, social and human capital through asset building, financial education and…
- Conditions
- Hunger, Child Development, Social Isolation
- Trial name
- NCT02577705
- Testing
- Self Empowerment Groups, Financial Empowerment, Matched Savings
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Center for Hunger-Free Communities
Coccydynia, Chronic Pain
Alexithymia, Pain Intensity, Quality of Life, and Psychological Symptoms in Chronic Coccydynia Patients Scheduled for Ganglion Impar Block
Chronic coccydynia is characterized by pain localized to the coccygeal region that typically worsens with sitting, leading to notable impairments in functional performance and health-related quality of life.
- Conditions
- Coccydynia, Chronic Pain, Alexithymia
- Trial name
- NCT07828145
- Testing
- Psychometric and Clinical Survey Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Maternal Depression, Self-Regulation, Emotion
Building Regulation in Dual Generations 2022-2025
This randomized control trial aims to investigate whether a novel intervention, the "Building Regulation in Dual Generations (BRIDGE)" program, improves mental wellness and parenting practices among mothers of 3 to 5-year-old…
- Conditions
- Maternal Depression, Self-Regulation, Emotion, Child Mental Disorder, Child Development
- Trial name
- BRIDGE (NCT05959538)
- Testing
- Building Regulation in Dual Generations (BRIDGE), Dialectical Behavioural Therapy Skill Training
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Myasthenia Gravis, Adverse Childhood Experience
Psychological Health and Adverse Childhood Experiences in Myasthenia Gravis: Online Mental Health BMI Learning Program
This study evaluated psychological health in patients with myasthenia gravis (MG) using an online behavioral program called the "Positive Mental Health BMI Learning Program." The program consisted of four short video units…
- Conditions
- Myasthenia Gravis, Adverse Childhood Experience, Psychological Well-being, Mental Well-being
- Trial name
- NCT07291713
- Testing
- Positive Mental Health BMI Learning Program
- Where
- Taiwan
- Volunteers
- 77 people
- Sponsor
- Jiann-Horng Yeh
Temporomandibular Disorder, Temporomandibular Joint Dysfunction
Trauma Exposure and Childhood Trauma in Temporomandibular Joint Disorders
Temporomandibular disorder is a multifactorial condition that involves the temporomandibular joint, masticatory muscles, and surrounding structures and is influenced by biological, psychological, and social factors.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Dysfunction, Trauma Exposure, Childhood Traumas
- Trial name
- NCT07292103
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Systemic Lupus Erythematosus
Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus
This study aims to investigate the feasibility and effectiveness of a remotely delivered psychological intervention for youth with cSLE.
- Trial name
- cSLE (NCT04335643)
- Testing
- TEACH
- Where
- 2 sites in United States, Canada
- Volunteers
- 65 people
- Sponsor
- Michigan State University
Perinatal Depression
Perinatal Depression and Adverse Childhood Experiences: Prevention Trial
The goal of this clinical trial is to evaluate the impact of ROSE in individuals with adverse childhood experiences. The main question it aims to answer is, compared to enhanced treatment as usual, does the delivery of ROSE…
- Trial name
- PPD-ACE (NCT05795114)
- Testing
- Reach Out, Stand Strong, Essentials for New Mothers (ROSE) Program
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Northwestern University
Depression
Childhood Adversity, Genetic Polymorphisms and Stress in First Onset Major Depression
The Blue Sky Project, a 5-year study funded by the Canadian Institutes of Health Research, seeks to examine how genetics and early life experiences work together to cause a person's very first onset of depression by increasing…
- Trial name
- NCT00517764
- Testing
- escitalopram
- Where
- 2 sites in Canada
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder (PTSD), Depression
A Study on the Efficacy of Virtual Reality Exposure Therapy (VRET) for Survivors of Childhood Sexual Abuse and War Related Trauma
Background: Childhood Sexual Abuse (CSA) and combat related war-trauma are associated with posttraumatic stress disorder (PTSD) and depression.
- Trial name
- NCT02234076
- Testing
- VRET, TAU
- Where
- 3 sites in Netherlands
- Volunteers
- 144 people
- Sponsor
- Erasmus Medical Center
Depression
Depression, Adversity, and Stress Hormones (DASH) Study
The stress-related hormone cortisol has been studied in depression for decades. However, relatively little is known about the role of cortisol in psychological features of depression.
- Trial name
- DASH (NCT03195933)
- Testing
- Cortisol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Social Skills, Perfectionism
Effectiveness of the Universal Prevention Program Super Skills for Life in Schools
This study aims to evaluate the effectiveness of a 12-session cognitive-behavioral transdiagnostic protocol for Spanish children aged 8 to 12 within an educational context, Super Skills for Life.
- Conditions
- Social Skills, Perfectionism, Self Esteem, Positive Affect
- Trial name
- NCT06444581
- Testing
- Super Skills Schools
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Anxiety, Depression
Detecting and Evaluating Childhood and Anxiety and Depression Effectively in Subspecialties
The DECADES trial seeks to determine the comparative effectiveness of specialist-centered management of anxiety and depression vs.
- Trial name
- DECADES (NCT02773706)
- Testing
- Automated Psychology Services, Notification of Subspecialist
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University