Clinical trials: Children Pain Management
Child, Hospitalized
Pharmacological and Non-pharmacological Interventions in Management of Venipuncture Pain.
To evaluate whether an integration of pharmacological and non- pharmacological interventions is more effective than either one of intervention in pain reduction during pediatric peripheral venipuncture.
- Trial name
- NCT04275336
- Testing
- EMLA application, Distraction techniques, EMLA cream and distraction techniques
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Children's Hospital of Fudan University
Pediatric Presentation of Urinary Tract Infection
Lidocaine Analgesia for Urethral Catheterization in Children
Primary Aim 1. To measure difference in pain via Faces, Legs, Activity, Cry and Consolability (FLACC) Pain Scale score at the time of transurethral bladder catheterization for urine collection in children who do and do not…
- Trial name
- NCT01780324
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Seattle Children's Hospital
Obstruction of Pelviureteric Junction
The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine
The investigators propose a prospective blinded randomized control trial (RCT) to assess the efficacy and safety of a simple method of continuous infusion of a local anesthetic, ropivacaine, via a surgical wound to control pain…
- Trial name
- NCT00930046
- Testing
- Ropivacaine wound catheter, Saline wound catheter
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Otitis
Dexmedetomidine vs Fentanyl for BMT
A randomized controlled clinical trial to examine effects of intranasal dexmedetomidine, an α2-adrenorecptor agonist, on pain control and agitation in children undergoing BMT.
- Trial name
- DexBMT (NCT00654329)
- Testing
- Saline, Fentanyl, Dexmedetomidine
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Supracondylar Humerus Fracture
Post-operative Pain Management in Children With Supracondylar Humerus Fractures
There are two common and concurrently used strategies for pain management following surgical treatment of supracondylar humerus (elbow) fractures in children: opioids vs over the counter pain medications.
- Trial name
- NCT05640674
- Testing
- Ibuprofen, Hydrocodone/acetaminophen, Acetaminophen
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Baylor College of Medicine
Supracondylar Humerus Fracture
Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management
This purpose of this study is to determine the efficacy of nonopioid versus opioid analgesic regimens following surgical fixation of Gartland Type III Supracondylar Humoral Fractures (SCHFs) to assist in the development of a…
- Trial name
- NCT06187584
- Testing
- Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Children's Mercy Hospital Kansas City
Breastfeeding, Exclusive, Pain, Acute
Promoting Self-Management of Breast and Nipple Pain With Technology (PROMPT) for Breastfeeding Women Study
Every year, 1 million women cease breastfeeding (BF) before 6 months, the minimum time required for optimal maternal and infant health, development, and well-being.
- Conditions
- Breastfeeding, Exclusive, Pain, Acute, Maternal Distress, Parent-Child Relations
- Trial name
- PROMPT (NCT05262920)
- Testing
- The BSM Intervention, Attention Control
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Pain
PREMIX vs PREMED Intranasal Lidocaine and Midazolam
Intranasal (IN) midazolam is an anxiolytic that is commonly used in the pediatric population for procedural anxiolysis in the emergency department (ED) setting to facilitate painful and distressing procedures, such as laceration…
- Trial name
- NCT03054844
- Testing
- Lidocaine, Lidocaine and midazolam (PREMIX), Midazolam
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Columbia University
Pain, Postoperative, Postoperative Nausea and Vomiting
Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery
There will be two groups in this study: one group will be given the standard infusion of naloxone, a drug which helps reduce side effects from opioids needed after surgery, and the other group will receive a higher dose.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Scoliosis
- Trial name
- NCT01531439
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Children's Mercy Hospital Kansas City
Orthopedic Disorder
Parental Perceptions on Prescription Opioid Use
This study involves an anonymous survey given to parents regarding their perceptions on prescription opioid use for pain control in children undergoing orthopedic surgery.
- Trial name
- NCT05344118
- Testing
- Survey
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Nationwide Children's Hospital
Obstructive Sleep Apnea
Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy
Pediatric tonsillectomy (with or without adenoidectomy) is a brief but painful surgery carried out in children who very often also present with obstructive sleep apnea. To provide pain relief, i.e.
- Trial name
- NCT00468052
- Testing
- dexmedetomidine, fentanyl
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Conscious Sedation
Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies
The role of Adjunct therapies such as Child Life therapy and Music listening during Procedural Sedation and Analgesia(PSA) for children during painful procedures has not been studied in the Emergency Department (ED).
- Trial name
- NCT02518919
- Testing
- Child life intervention, Music listening
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Children's Hospital of Michigan
Abscess, Pain
Efficacy of Intranasal Fentanyl at Reducing Pain During Abscess Incision and Drainage (I&D) in Children
Children can develop abscesses (a collection of pus under their skin) that require a physician to cut it open to let the pus drain out. This is a painful procedure.
- Trial name
- NCT01549002
- Testing
- Intranasal Fentanyl, Intravenous Morphine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Tympanomastoid Surgery, Cochlear Implant
Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery
The investigators goal is to determine the efficacy and duration of analgesia with the addition of Clonidine, an alpha-2 agonist, to local anesthetic blockade using bupivacaine, of the great auricular nerve in children undergoing…
- Conditions
- Tympanomastoid Surgery, Cochlear Implant, Mastoidectomy, Cholesteatoma
- Trial name
- NCT01638052
- Testing
- 0.25% Bupivacaine + Clonidine
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Adenotonsillectomy, Post-operative Analgesia
Non-opioids for Analgesia After Adenotonsillectomy in Children
The goal of this study is to determine if non-opioid pain control is a safe way to manage pain after adenotonsillectomy surgery in children.
- Conditions
- Adenotonsillectomy, Post-operative Analgesia, Opioid Use
- Trial name
- NCT03618823
- Testing
- Oxycodone, Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- David Chi, MD
Idiopathic Scoliosis, Spondylolisthesis
Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia
The purpose of this study is to: 1. Establish whether ketamine can decrease opioid consumption and modulate the onset of opioid tolerance and prevent opioid-induced hyperalgesia in pediatric subjects, ages 10 years to 18 years…
- Trial name
- KPSF (NCT01325493)
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Julia Finkel
Musculoskeletal Injury
Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries
Pain management for children presenting to the emergency department (ED) with an injured limb is often under-treated, even though it is known that broken arms and legs cause moderate to severe pain.
- Trial name
- NCT02064894
- Testing
- oral morphine and oral ibuprofen, Oral morphine, Oral ibuprofen
- Where
- 3 sites in Canada
- Volunteers
- 501 people
- Sponsor
- St. Justine's Hospital
Spastic Cerebral Palsy
Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
The purpose of this proposal is to improve the investigators' current Selective Dorsal Rhizotomy (SDR) analgesia protocol by eliminating or minimizing the use of fentanyl in the post-operative period.
- Trial name
- NCT00955877
- Testing
- Extended-release Epidural morphine (EREM) 80, Extended-release Epidural Morphine (EREM) 120, Control: Saline
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Inguinal Herniorrhaphy, Orchiopexy
Preemptive Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block) is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et…
- Trial name
- NCT00616577
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loma Linda University
Post Operative Pain
Parent Nurse Controlled Analgesic in Pediatric Patients With Developmental Delay
The purpose of this study is to compare, the safety, efficacy and level of parent and nurse satisfaction with three methods of opioid administration post-operatively in children (4-18 years of age) with developmental delay.
- Trial name
- PNCA (NCT00743730)
- Testing
- Pain and standard side effect management for PNCA with basal method., Pain and standard side effect management with PNCA without basal, Pain and standard side effect management with IV on an as needed basis method.
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Medical College of Wisconsin