Clinical trials: Chlamydia Trachomatis
Trachoma, Chlamydia Trachomatis
Impact of Two Alternative Dosing Strategies for Trachoma Control in Niger
Trachoma is a disease of poverty, which in the hyperendemic areas affects all individuals by the time they are two years old. Active disease is concentrated in children and occurs sporadically in adults.
- Trial name
- NCT00618449
- Testing
- Azithromcyin, Azithromycin
- Where
- 2 sites in United States, Niger
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chlamydial Infection, Gonococcal Infection
Clinical Study of a Diagnostic Device for NG, TV and CT in Women
This is a multi-center study with a minimum of three sites in the United States. The study will enroll approximately 1750 female subjects, 14 years of age and older, and will have a study duration of approximately 9 months after…
- Conditions
- Chlamydial Infection, Gonococcal Infection, Trichomoniasis
- Trial name
- NCT03852316
- Testing
- Click Device
- Where
- 10 sites in United States
- Volunteers
- 1,585 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chlamydia Trachomatis
Safety of Chlamydia Vaccine CTH522 in Healthy Women Aged 18 to 45 Years
The present trial is a phase I first in human, double blind, parallel and placebo controlled trial of SSI's adjuvanted chlamydia vaccine CTH522: CTH522-CAF01 (CAF01 is an adjuvant system) and CTH522-Al(OH)3.
- Trial name
- NCT02787109
- Testing
- CTH522-CAF01, CTH522-Al(OH)3
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Statens Serum Institut
Sexually Transmitted Diseases, Gonorrhea
Evaluation of EVO100 for Prevention of Urogenital Chlamydia Trachomatis and Neisseria Gonorrhoeae Infection
This study will evaluate whether EVO100 vaginal gel prevents the sexual transmission of CT and GC infection
- Conditions
- Sexually Transmitted Diseases, Gonorrhea, Chlamydia
- Trial name
- EVOGUARD (NCT04553068)
- Testing
- EVO100
- Where
- 98 sites in United States
- Volunteers
- 1,892 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.
Chlamydia Trachomatis Infection
Genital CT Treatment to Pregnant Women to Prevent Adverse Pregnancy Outcomes: A Pilot RCT
This study aims to identify the relationship between genital C. trachomatis and adverse pregnancy outcomes, and investigate whether screening and treatment of genital C.
- Trial name
- RCT (NCT03862495)
- Testing
- C. trachomatis and N. gonorrhoeae, Azithromycin, Partner notification and treatment
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bacterial Vaginosis, Vaginal Microbiome
Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIs
HIV remains a global pandemic with 37 million infected. In western Kenya, 16% of women in the general population and 29% of the poorest women have HIV.
- Conditions
- Bacterial Vaginosis, Vaginal Microbiome, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
- Trial name
- POWWERHealth (NCT05666778)
- Testing
- Menstrual Cup
- Where
- 2 sites in United States, Kenya
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
Clinical Evaluation of the ID NOW™ CT/NG Test
The objective of this study is to determine the performance of the ID NOW™ CT/NG test in male urine, female urine, and self-collected vaginal swabs when tested by intended users (i.e., untrained operators).
- Conditions
- Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Asymptomatic Condition
- Trial name
- NCT06395675
- Testing
- ID NOW™
- Where
- United States
- Volunteers
- 7,100 people, healthy volunteers welcome
- Sponsor
- Abbott Rapid Dx
Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection
NeuMoDx PrEDiCTiNG Study Evaluation Plan
This investigational study will be conducted to evaluate the performance of the NeuMoDx™ CT/NG Assay on the NeuMoDx™ 288 Molecular System and NeuMoDx™ 96 Molecular System (collectively referred to as NeuMoDx™ CT/NG Assay test…
- Trial name
- NCT03970850
- Testing
- NeuMoDx CT/NG Assay, FDA-cleared NAATs
- Where
- 15 sites in United States
- Volunteers
- 4,017 people, healthy volunteers welcome
- Sponsor
- NeuMoDx Molecular, Inc.
Chlamydia Trachomatis, Gonorrhea
Evaluation of the Atlas Genetics io® CTNG System
Atlas Genetics io® system results are compared with those obtained from comparator devices.
- Trial name
- IO-CTNG (NCT03071510)
- Testing
- Atlas Genetics io® system
- Where
- 10 sites in United States
- Volunteers
- 7,128 people, healthy volunteers welcome
- Sponsor
- Binx Health Limited
Sexually Transmitted Diseases
Clinical Evaluation of Visby Medical Men's Sexual Health Test
This is a multi-center study in which the performance of the Visby Medical Men's Sexual Health Test is evaluated when run by male subjects of 14 years of age and older on self-collected first catch urine samples using the…
- Trial name
- NCT07659808
- Testing
- Visby Medical Men's STI PCR Test Kit
- Where
- 5 sites in United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Visby Medical
Antenatal Health, Antenatal Care
Healthy Expectancy Through Routine Antenatal STI Screening
This study will evaluate whether routine screening and treatment for two common sexually transmitted infections, chlamydia and gonorrhoea, during pregnancy can reduce preterm birth and other poor birth outcomes in Botswana, and…
- Conditions
- Antenatal Health, Antenatal Care, STI, Chlamydia Trachomatis Infection in Pregnancy
- Trial name
- HERA (NCT07458802)
- Testing
- Chlamydia trachomatis and Neisseria gonorrhoeae screening
- Where
- Botswana
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Adriane Wynn
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission
The primary aims of the study were to assess the safety and acceptability of Carraguard ™ (PC-515) when applied vaginally at least three times weekly for 6-12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213018
- Testing
- Carraguard (PC-515)
- Where
- 2 sites in South Africa
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Population Council
Chlamydia Trachomatis Infection, Gonorrhea
Check it: A New Approach to Controlling Chlamydia Transmission in Young People
This study, named "Check it," is a bundled program for African American (AA) men ages 15-24 that includes community testing for chlamydia and gonorrhea, expedited treatment for subjects who test positive and their female sexual…
- Trial name
- NCT03098329
- Testing
- Ct/GC screening
- Where
- United States
- Volunteers
- 1,907 people, healthy volunteers welcome
- Sponsor
- Tulane University
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide
The primary aims of the study were to assess the safety and acceptability of PC-515 when applied vaginally at least three times weekly for 12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213031
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Population Council
HIV Infections, Sexually Transmitted Diseases
Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe
This is a prospective cohort study evaluating acceptability, feasibility, and effectiveness of integrating HIV pre-exposure prophylaxis (PrEP) into a sexually transmitted infection (STI) clinic alongside assisted partner…
- Conditions
- HIV Infections, Sexually Transmitted Diseases, Blood-Borne Infections, Communicable Disease
- Trial name
- NCT05307991
- Testing
- PrEP, STI testing, Assisted partner notification
- Where
- Malawi
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
STI, Mycoplasma Genitalium Infection
Mycoplasma Genitalium Infection and Associated Antimicrobial Resistance Among HIV-infected Male in Hong Kong
Worldwide, Mycoplasma genitalium (MG) is increasingly reported as an emerging cause of sexually transmitted infections. Internationally, the prevalence of MG is higher in male with urethritis and community groups especially among…
- Trial name
- NCT05789134
- Testing
- self-sampling kits for STI testing in the laboratory
- Where
- Hong Kong
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Chlamydia Trachomatis, Infertility
Randomized Population-Based Study on Chlamydia Trachomatis Screening
30,000 individuals living in Aarhus County, Denmark by Oct 1997 were randomized into two groups. The intervention group received an invitation to be tested for urogenital Chlamydia trachomatis by use of home-obtained and mailed…
- Conditions
- Chlamydia Trachomatis, Infertility, Ectopic Pregnancy
- Trial name
- NCT00827970
- Testing
- Screening for urogenital Chlamydia trachomatis
- Where
- Denmark
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
STI
Population Burden of STI and Implication for Intervention in Hong Kong
This is a 5-year cross-disciplinary sexually transmitted infection (STI) project involving a) territory-wide and community-based studies (survey and specimen collection); b) simulation of STI transmission dynamics and comparison…
- Trial name
- NCT04793841
- Testing
- self-sampling kits for STI testing in laboratory
- Where
- Hong Kong
- Volunteers
- 1,977 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Trachoma
Study of Three Alternatives for Mass Treatment in Trachoma Villages of Tanzania
After single, yearly, mass treatment of communities with azithromycin for active trachoma, what is the added effectiveness for reduction of trachoma and ocular C.
- Trial name
- NCT00347607
- Testing
- community surveillance and re-treatment
- Where
- 2 sites in United States, Tanzania
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chlamydia Trachomatis Infection
Phase 2B/3 Double-blinded Placebo-controlled
Phase 2B double-blind placebo-controlled efficacy trial of EVO100 (previously known as Amphora ® Gel) for the prevention of acquisition of urogenital Chlamydia trachomatis infection
- Trial name
- NCT03107377
- Testing
- EVO100
- Where
- 50 sites in United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Evofem Inc.