Clinical trials: Cholesterol
Cardiovascular Disease
A Study Examining Effects of Apples/ Apple Products on Heart Disease Risk
This study will examine if health benefits of consuming nutrient-rich apples, an apple extract and freeze dried apple product will be similar.
- Trial name
- APPS (NCT01585519)
- Testing
- High/ Low Epicatechin Apples/ Apple Extract/ Granules
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Dyslipidemias, Hypercholesterolemia
Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol Ester
Efficacy of plant stanols as esters on LDL-cholesterol reduction is well documented. LDL-cholesterol lowering efficacy of the ingredient in a biscuit (providing 2 g plant stanols as esters per day) is less well known.
- Conditions
- Dyslipidemias, Hypercholesterolemia, Hyperlipidemias
- Trial name
- NCT02331043
- Testing
- Plant stanol ester
- Where
- Thailand
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Raisio Group
CVD, Cholesterol; Metabolic Disorder
Omega (n)-3 PUFA Enriched Beef & Health Outcomes.
Red meat is an integral component of the habitual diet among the UK and Irish population, with adults consuming an average of 71grams/day.
- Conditions
- CVD, Cholesterol; Metabolic Disorder, Inflammation
- Trial name
- NCT03967678
- Testing
- Three portions per week (690g beef (raw weight)) for 5 weeks
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Rheumatoid Arthritis
Effects Of CP-690,550 (Tasocitinib) On Cholesterol Metabolism In Patients With Active Rheumatoid Arthritis
The purpose of study is to explore the effect of CP-690,550 (tasocitinib) on cholesterol metabolism in patients with active rheumatoid arthritis (RA).
- Trial name
- NCT01262118
- Testing
- CP-690,550 (tasocitinib)
- Where
- 11 sites in United States, Hungary
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Pfizer
Diabetes Mellitus, Normal Glucose Metabolism
Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients
This study will examine whether fasting and non-fasting lipid measures can provide similar clinical information in order to guide lipid management by primary physicians. It will compare fasting vs.
- Conditions
- Diabetes Mellitus, Normal Glucose Metabolism, Hyperlipidemia
- Trial name
- NCT00569959
- Testing
- fasting 12+ hours, Non-fasting
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Hypercholesterolemia
Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Spain)
The purpose of this study is to investigate the cholesterol lowering effect of a drinkable low fat fermented milk enriched with plant sterol after 3 and 6 weeks in mildly hypercholesterolemic subjects treated or not by statins.
- Trial name
- NCT01600820
- Testing
- 1- Low fat drinkable fermented dairy product enriched with 1.6g of plant sterol (as free equivalent) per unit, 2- Low fat drinkable fermented dairy product enriched with 2.0g of plant sterol (as free equivalent) per unit, 3- Low fat drinkable fermented dairy product without plant sterols(control)
- Where
- Spain
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Danone Spain
Hypercholesterolaemia
Dose Effect of Limicol on (LDL)-Cholesterol Levels
The principal objective of this study is to investigate the dose-effect of the Limicol food supplement on LDL-cholesterol level in moderate hypercholesterolaemia subjects.
- Trial name
- NCT01354340
- Testing
- Limicol
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Lescuyer Laboratory
Cholesterol; Lipidosis
Can Mindful Eating Improve Cholesterol and Glucose Level
This study aims to explore the effectiveness of mindful eating and its effect on cholesterol and glucose level. The participants will be required to get tested for their fasting total cholesterol and blood glucose level for two…
- Trial name
- NCT04833595
- Testing
- Mindfulness practice
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia
Hypercholesterolemia
Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian Adults
To evaluate the effects of daily consumption of 3 capsules of Swisse Nutra+ Cholesterol Balance on serum LDL-cholesterol in adults with hypercholesterolaemia compared to placebo over four months.
- Trial name
- CLoNE (NCT04783714)
- Testing
- Swisse Nutra+ Cholesterol Balance
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Swisse Wellness Pty Ltd
Healthy
Comparison of Colesevelam Hydrogen Chloride (HCl) Powder For Oral Suspension Versus Generic Cholestyramine Through Use of the Bile Acid Sequestrant Acceptability (BASA) Scale
The objective of this study is to compare the acceptability of Colesevelam HCl powder for oral suspension versus generic cholestyramine via the BASA scale, based upon an anticipated equivalent cholesterol lowering doses of each…
- Trial name
- NCT01122108
- Testing
- Cholestyramine, Colesevelam HCl
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Louisville Metabolic and Atherosclerosis Research Center
Brain Activity, Appetite
Effects of Protein and Fiber at Breakfast on Appetite, Blood Sugar, and Cholesterol
The objectives of the research are to assess the effects of increased protein and fiber intake at breakfast on neural activation in brain regions associated with appetitive drive and reward-driven eating, measures of subjective…
- Conditions
- Brain Activity, Appetite, Ingestive Behavior, Glucose Control
- Trial name
- PFB (NCT02169245)
- Testing
- Dietary control of protein and fiber intake at breakfast
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Coronary Artery Disease
Effect of Exercise Training on the Function of HDL-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Coronary Artery Disease (HERCET-Study)
Patients with coronary artery disease are characterized by an increased cardiovascular risk and they often have low blood high density lipoprotein (HDL)-cholesterol levels or HDL-cholesterol with modified vasculoprotective…
- Trial name
- HERCET (NCT00457379)
- Testing
- physical exercise
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Hypercholesterolemia
Study on the Effect of the Intake of a Calcium-bicarbonate Water on Cholesterol Levels
The goal of this study is to evaluate the hypolipidemic effect (reduction of Low Density Lipoprotein Cholesterol "LDL-C" values) of calcium-bicarbonate mineral water "Lete" (alkaline water, high in bicarbonate and calcium ions…
- Trial name
- NCT07026266
- Testing
- Water
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Società Generale delle Acque Minerali S.p.A.
Healthy
AStudy to Evaluate the Bioavailability of PF 04965842 in Healthy Subjects
Phase 1, open label, single dose, 3 way crossover study to evaluate the bioavailability of a solid dose formulation of PF 04965842 relative to a suspension formulation under fasting conditions and the effect of food on the…
- Trial name
- NCT02163161
- Testing
- PF-04965842, PF- 04965842
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Hyperlipidemia, Cardiovascular Diseases
The Effect of Strawberries in a Cholesterol-Lowering Dietary Portfolio
The purpose of this study is to determine whether addition of strawberries to a dietary portfolio of cholesterol-lowering foods will improve compliance and so increase the effectiveness of the dietary portfolio in lowering…
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Hypercholesterolemia
- Trial name
- NCT00345722
- Testing
- strawberry dietary intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cholesterol, Cholesterol (total and HDL)
Natural Heart Health Supplement Trial
We are running a 3-month trial of an experimental natural heart health supplement. Participants will take a daily dose of an experimental natural heart health supplement in powdered format, chocolate flavor.
- Trial name
- NCT06671769
- Testing
- Heart Health Supplement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Hypercholesterolemia
Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic Subjects
The objective of the study is to elucidate the effects of lupin protein (Lupinus angustifolius Boregine) as part of a mixed diet on cardiovascular risk factors and to clarify the role of arginine, one of the most abundant amino…
- Trial name
- NCT01598649
- Testing
- Fabricated foods with lupin protein, Mannitol, Arginine
- Where
- Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Jena
Atherosclerosis, Hypercholesterolemia
Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With Dyslipidemia
Atherosclerosis is the leading cause of death and disability in adults. However, investigations suggest that the basic pathology of heart disease as more severe myocardial infarction which usually reach mainly middle-aged or…
- Trial name
- NCT01581697
- Testing
- Oat bran
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Low HDL Cholesterol
Association Between HDL Functions and Atherosclerotic Burden in Healthy Individuals
This is a study of HDL function in healthy individuals classified in three groups according to their HDL-cholesterol levels (Low HDL-C, Intermediate HDl-C and High HDL-C), with the purpose of investigating which characteristics…
- Trial name
- NCT02106013
- Where
- Brazil
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil