Clinical trials: Chorioretinopathy
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy: Etiology, Course and Prognosis
Pathogenesis of central serous chorioretinopathy is not entirely understood yet, therefore further investigations are needed. During this study patients with an acute episode of central serous chorioretinopathy are observed with…
- Trial name
- NCT01378130
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Central Serous Chorioretinopathy
the Study of the Association Between the Gut Microbiota and Central Serous Chorioretinopathy
To investigate the potential association between gut microbiota and central serous chorioretinopathy (CSC), clinical observations have indicated that patients with CSC frequently present with chronic gastrointestinal symptoms.
- Trial name
- NCT06527326
- Testing
- Live Combined Bifidobacterium
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Central Serous Chorioretinopathy
577nm Micropulse Laser vs Half-dose Photodynamic Therapy on Acute Central Serous Chorioretinopathy
The purpose of this study is to determine whether micropulse laser (MPL) is different to half-dose photodynamic therapy on acute central serous chorioretinopathy.
- Trial name
- NCT02587767
- Testing
- 577-MPL, HD-PDT
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Sun Yat-sen University
Autoimmune Diseases, Ulcerative Colitis
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
The most clinically meaningful way to discover new targets of T cells in autoimmune diseases is to study the tissues of patients with active autoimmune disease mediated organ inflammation.
- Conditions
- Autoimmune Diseases, Ulcerative Colitis, Multiple Sclerosis, Scleroderma
- Trial name
- NCT06587828
- Testing
- Companion blood samples with procedure
- Where
- 11 sites in United States
- Volunteers
- 238 people
- Sponsor
- TScan Therapeutics, Inc.
Central Serous Chorioretinopathy
The Effect of Therapy With Bevacizumab in Chronic Central Serous Chorioretinopathy
The pathophysiology of central serous chorioretinopathy remains controversial. traditional treatment is laser photocoagulation or photodynamic therapy.Recently Bevacizumab (Avastin, Genetech),an antibody to vascular endothelial…
- Trial name
- NCT00864773
- Testing
- intravitreal injection with anterior paracentesis
- Volunteers
- 10 people
- Sponsor
- Hallym University Medical Center
Central Serous Chorioretinopathy
Intravitreal Ranibizumab Treatment of Central Serous Chorioretinopathy
The purpose of this study is to examine the effects of Lucentis for active Central Serous Chorioretinopathy.
- Trial name
- NCT00403325
- Testing
- rhuFab V2 [ranibizumab] ( Lucentis )
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Vitreous -Retina- Macula Consultants of New York
Central Serous Chorioretinopathy
Navigated Microsecond Laser for Chronic Central Serous Chorioretinopathy: MICROPULSE
MICROPULSE study aims to evaluate the efficacy of navigated microsecond laser (nMSL) for chronic central serous chorioretinopathy (CSCR).
- Trial name
- MICROPULSE (NCT05679180)
- Testing
- micropulse laser
- Sponsor
- University Hospital, Bordeaux
Chronic Central Serous Chorioretinopathy
Eplerenone Treatment for Chronic Central Serous Chorioretinopathy in Hungarian Population
The aim of the study is to determine the efficacy and safety of treatment with the drug eplerenone in patients with chronic central serous chorioretinopathy.
- Trial name
- NCT02462499
- Testing
- Inspra (eplerenone)
- Where
- Hungary
- Volunteers
- 28 people
- Sponsor
- Semmelweis University
Chronic Central Serous Chorioretinopathy
Microperimetric Evaluation After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
A half-dose photodynamic therapy, a relative new treatment, has been widely performed to treat central serous chorioretinopathy.
- Trial name
- NCT01434095
- Testing
- half-dose photodynamic therapy
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Surugadai Nihon University Hospital
Central Serous Chorioretinopathy
Multimodal Imaging in Central Serous Chorioretinopathy
This study aims to assess the contribution of the multimodal imaging, combining a routine examination using Optical Coherence Tomography (OCT) with an imaging procedure using adaptive optics retinal camera.
- Trial name
- IMO (NCT02889185)
- Testing
- RTX1 IMAGIN EYE retinal camera
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Central Serous Chorioretinopathy
Central Serous Chorioretinopathy Treated by Modified Photodynamic Therapy
The purpose of this study is to evaluate the effectiveness as well as the detrimental influence of half-dose and half-fluence modification of verteporfin photodynamic therapy (PDT) for the treatment of prolonged unresolved…
- Trial name
- NCT01019668
- Testing
- Verteporfin PDT, half-dose, verteporfin PDT, half-fluence
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Central Serous Chorioretinopathy
A Study of the Beneficial Effects of Eplerenone on Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is supposedly the fourth most common non-surgical retinopathy after age-related macular degeneration, diabetic retinopathy and branch retinal vein occlusion.
- Trial name
- NCT02215330
- Testing
- Eplerenone, Maltodextrin
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Central Serous Chorioretinopathy
Eplerenone Versus PDT: Comparative Study by OCTA
The study aims to analyze the changes in OCTA parameters and in choroidal thickness in patients affected by central serous chorioretinopathy treated by oral eplerenone and half-fluence photodynamic therapy.
- Trial name
- NCT05104138
- Testing
- Eplerenone, The patients underwent half fluence photodynamic therapy for 6 months
- Volunteers
- 30 people
- Sponsor
- Federico II University
Central Serous Chorioretinopathy
Choroidal Blood Flow in Acute and Chronic Central Serous Chorioretinopathy
Patients with central serous chorioretinopathy (CSC) will be monitored with laser speckle flow graphy (LSFG), swept source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA).
- Trial name
- NCT05589974
- Testing
- Verteporfin
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Central Serous Retinopathy (CSR)
Eye Patch Therapy for Central Serous Retinopathy (CSR)
First, this study will investigate the viability of 24-hour eye patching as a potential treatment modality for CSR. Second, this study will assess a potential physiologic explanation for CSR, namely if inhibition of photic…
- Trial name
- NCT02036632
- Testing
- Eye Patching
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Washington University School of Medicine
Age-Related Macular Degeneration, Diabetic Maculopathy
Selective RPE Laser Treatment (SRT) for Various Macular Diseases
In this prospective clinical study SRT is performed with various pulse durations at 1.7µs and additionally 200ns to evaluate the different clinical effects of both laser regimens.
- Conditions
- Age-Related Macular Degeneration, Diabetic Maculopathy, Central Serous Chorioretinopathy
- Trial name
- NCT00403884
- Testing
- Selective RPE laser treatment
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Regensburg
Central Serous Chorioretinopathy
Comparison of Multifocal Electroretinogram Assessment in Chronic Central Serous Chorioretinopathy (CSC) Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
This study is a comparison of multifocal electroretinogram assessment between the laser treatment group and the photodynamic therapy group in chronic central serous chorioretinopathy.
- Trial name
- NCT00803517
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Chronic Central Serous Chorioretinopathy
A Pilot Study of the Treatment of Central Serous Chorioretinopathy With Ketoconazole
The purpose of this study is to determine the effect of an adrenocorticoid antagonist (ketoconazole), 600 mg per day for 4 weeks, in the treatment of patients with central serous chorioretinopathy (CSC).
- Trial name
- CSC/Keto (NCT00211393)
- Testing
- ketoconazole
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Central Serous Chorioretinopathy, Tomography, Optical Coherence
Effects of OCTA-guided PDT in Acute CSC
OCTA-guided PDT is as safe and effective as ICGA-guided PDT in the treatment of acute central serous chorioretinopathy. Or OCTA-guided PDT is more effective than ICGA-guided PDT in the treatment of acute central serous…
- Trial name
- NCT03497000
- Testing
- OCTA-guided Photodynamic therapy, ICGA-guided Photodynamic therapy
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Peking University People's Hospital
Chronic Central Serous Chorioretinopathy
Pseudo-PDT in Central Serous Chorioretinopathy
Acute central serous chorioretinopathy (CSC) is a common disorder in middle-aged patients, characterized by serous retinal detachment in the macular region.
- Trial name
- NCT02799992
- Testing
- 689 nm Laser Treatment of the Macula, Half Dose Photodynamic Therapy
- Volunteers
- 22 people
- Sponsor
- Università degli Studi di Brescia