Clinical trials: Chronic Brain Injury
Chronic Traumatic Encephalopathy, Traumatic Encephalopathy, Chronic
Cohort Study of Blood Biomarkers for TES
In this study, high-throughput screening and multi-omics (transcriptomics and proteomics) joint analysis technology will be employed to explore potential CTE/TES biomarkers (RNA and protein) in blood and its exosomes.
- Conditions
- Chronic Traumatic Encephalopathy, Traumatic Encephalopathy, Chronic, Traumatic; Encephalopathy, Postcontusional
- Trial name
- NCT04928534
- Testing
- Blood tests, Cognitive function tests, head MRI (plain scan and DTI sequence) examination and head PET (FDG-PET, Tau-PET and Amyloid-PET) examination
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Cerebral Palsy, Crouch Gait
Alterations of Functional Activities and Leg Stiffness After Hamstring Lengthening in Cerebral Palsy Children
Cerebral palsy (CP) is the most prevalent physical disabilities originating in childhood. Crouch gait is a common gait abnormality in patients with cerebral palsy, which is common treated with hamstring lengthening.
- Trial name
- NCT00154830
- Testing
- cerebral palsy, crouch gait
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy, Prematurity
Best Practices Fo Early Diagnosis of Cerebral Palsy
In this research, the investigators are using an implementation science approach to enhance the uptake of a clinical practice guideline for earlier diagnosis of cerebral palsy (i.e.
- Trial name
- CP (NCT06537622)
- Testing
- Implementation group, Standard of care
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Cerebral Palsy
Status of People With Cerebral Palsy and Their Caregivers During COVID-19 Pandemic
COVID-19, as well as the collateral situations that it entails, has been causing panic, anguish and anxiety that has generated biopsychosocial problems in society affecting not only the physical and social level but also the…
- Trial name
- NCT04753632
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Cerebral Palsy
Fitts Law in People With Cerebral Palsy
Introduction: Cerebral palsy (CP) is a non-progressive disorder in the brain which makes the control and execution of movements difficult.
- Trial name
- NCT03002285
- Testing
- Cerebral Palsy group, Control group
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cerebral Palsy
ImGTS for Patients With Cerebral Palsy and With Mobility Limitations
The proposed research project aims to answer the question "Are immersive technology systems effective in the rehabilitation management of pediatric patients with cerebral palsy and with mobility limitations?".
- Trial name
- NCT05299905
- Testing
- Virtual reality using Semi-CAVE, Virtual reality using the HMD
- Where
- Philippines
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Augmented eXperience E-health Laboratory
Cerebral Palsy
Comparison of Somatometric Characteristics Between Cerebral Palsy and Normal Children, Cross-sectional, Multi Center Study
The purpose of this study is to: 1) secure basic data of patients with cerebral palsy, 2) seek ways to simplify the data for clinical application, 3) progress of hip dislocation, presence or absence of hip surgery, and The…
- Trial name
- NCT04489498
- Where
- South Korea
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Feeding Behavior, Sensory Integration Disorder
Feeding Behavior Intervention in Children with Cerebral Visual Impairment
This study was planned to investigate the effects of nutritional education given in addition to sensory integration intervention on feeding behavior, sensory processing and developmental areas in children with Cerebral Visual…
- Conditions
- Feeding Behavior, Sensory Integration Disorder, Cerebral Visual Impairment
- Trial name
- NCT06827743
- Testing
- feeding behavior education, Sensory integration intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Spinal Cord Injury
Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury
The purpose of this study is to determine whether the novel treatment of transcranial direct current stimulation (tDCS) could decrease the pain perception of those with spinal cord injury.
- Trial name
- NCT01112774
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Cerebral Palsy
Optimizing Assisted Communication Devices for Children With Motor Impairments Using a Model of Information Rate and Channel Capacity
For children who depend on devices to communicate, the rate of communication is a primary determinant of success. For children with motor impairments, the rate of communication may be limited by inability to contact buttons or…
- Trial name
- NCT00352326
- Testing
- reprogramming assisted communication device interface
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cerebral Palsy
The Effect of Botox on Children With Cerebral Palsy
Botulinum toxin injections are a common form of treatment for children with cerebral palsy to help reduce muscle tightness and help them walk without resorting to surgery.
- Trial name
- NCT00503620
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Disorder of Consciousness, Minimally Conscious State
Simultaneously PET/MRI in Prolonged DOC Patients
Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary…
- Conditions
- Disorder of Consciousness, Minimally Conscious State, FDG-PET, Rs-fMRI
- Trial name
- NCT04164680
- Testing
- Multimodal Neuroimaging
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hangzhou Normal University
COVID-19, Disabilities Multiple
COVID-19 Pandemic and Parents of Disabled Children
Pandemic period could affect the disabled children's rehabilitation and follow-up negatively because of preventive measures and this could create adverse results on their parents.
- Conditions
- COVID-19, Disabilities Multiple, Cerebral Palsy, Muscular Dystrophies
- Trial name
- NCT04525742
- Testing
- Difficulties lived by disabled children's parents in the period of COVID-19 pandemic
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Disorder of Consciousness
A Promising Tool for Predicting Consciousness Evolution in Prolonged Disorders of Consciousness
The research contains two parts. Part 1: To explore whether EEG responses to zolpidem can assess consciousness circuit integrity and predict the evolution of consciousness in patients with prolonged disorders of consciousness…
- Trial name
- NCT02948660
- Testing
- Zolpidem Tartrate Tablets
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Cerebral Palsy, Diplegic Cerebral Palsy
The Relationship Between Upper Extremity Functionality, Trunk Control and Balance in Children With Cerebral Palsy
The aim of this study is to examine the relationship between trunk control, upper extremity functionality and balance in children with cerebral palsy and to compare this relationship with healthy sedentary children.This study is…
- Conditions
- Cerebral Palsy, Diplegic Cerebral Palsy, Balance; Distorted
- Trial name
- NCT06378723
- Testing
- Balance Tests
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cerebral Palsy, Spastic
The Relationship Between Functional Exercise Capacity, Respiratory Muscle Strength, Trunk Control, Balance and Activities of Daily Living in Individuals With Cerebral Palsi
Cerebral palsy (CP) causes problems in posture, movement, breathing, postural control and balance in individuals. This work; This study was conducted to examine the relationship between functional exercise capacity, respiratory…
- Trial name
- NCT05682079
- Testing
- TCMS, PEDİ, respiration, GMFCS,PBS,functional capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nursena Güçlü
Traumatic Brain Injury
Treating Traumatic Brain Injury With Transcranial Direct Current Stimulation
Traumatic Brain Injury (TBI) often results in a wide array of cognitive impairments, which can significantly diminish quality of life for affected individuals.
- Trial name
- NCT06989970
- Testing
- Active tDCS on the DLPFC + Cognitive Intervention(s)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Subdural Hematoma
Association Between Dietary Factors and Chronic Subdural Hematoma (DISH)
A prospective, multicenter, case control trial is designed to compare difference in dietary and nutritional factors in patients with and without chronic subdural hematoma.
- Trial name
- DISH (NCT05599217)
- Testing
- Dietary and nutritional questionnaire, Neurological function, cognitive function, and life quality assessment, Peripheral blood test
- Where
- 4 sites in China
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Traumatic Brain Injury, Chronic Traumatic Encephalopathy
Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury
The potential long-term effects of Traumatic Brain Injury (TBI) are poorly understood. Repeated concussions have been associated with an elevated incidence of Alzheimer's disease (AD) along with a reduced age of onset.
- Conditions
- Traumatic Brain Injury, Chronic Traumatic Encephalopathy, Mild Cognitive Impairment
- Trial name
- NCT02266563
- Testing
- Amyvid PET Scan, T807 PET scan
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samuel Gandy