Clinical trials: Chronic Central Serous Chorioretinopathy
Chronic Central Serous Chorioretinopathy
Prospective Randomized Controlled Treatment Trial for Chronic Central Serous Chorioretinopathy
Chronic central serous chorioretinopathy (CSC) is a relatively frequent eye disease that often occurs in patients in the professionally active age range.
- Trial name
- PLACE (NCT01797861)
- Testing
- Half-dose photodynamic therapy (PDT), Micropulse laser (ML) treatment
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 140 people
- Sponsor
- Radboud University Medical Center
Central Serous Chorioretinopathy, Micropulse Laser
Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included.
- Conditions
- Central Serous Chorioretinopathy, Micropulse Laser, Photodynamic Therapy
- Trial name
- NCT06468540
- Volunteers
- 60 people
- Sponsor
- Beijing Hospital
Central Serous Chorioretinopathy
Comparison of Multifocal Electroretinogram Assessment in Chronic Central Serous Chorioretinopathy (CSC) Between Laser Treatment Group and Photodynamic Therapy Group in Chronic Central Serous Chorioretinopathy
This study is a comparison of multifocal electroretinogram assessment between the laser treatment group and the photodynamic therapy group in chronic central serous chorioretinopathy.
- Trial name
- NCT00803517
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Samsung Medical Center
Chronic Central Serous Chorioretinopathy
Photodynamic Therapy Using Verteporfin for Treatment of Chronic Central Serous Chorioretinopathy (CSC)
Central serous choroidal (CSC) retinopathy is a disease of the macula characterized by exudation of fluid under the retina localized to the posterior pole as well as loss of vision.
- Trial name
- NCT00211445
- Testing
- Photodynamic Therapy with Verteporfin, verteporfin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Central Serous Chorioretinopathy
Micropulse Diode Laser Treatment for Chronic Central Serous Chorioretinopathy
The aim of this study was to evaluate safety and therapeutic response to micropulse diode 810nm laser treatment in patients with chronic central serous chorioretinopathy.
- Trial name
- NCT01327170
- Testing
- Subthreshold diode micropulse laser
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Federal University of São Paulo
Retinal Disease
Finasteride for Chronic Central Serous Chorioretinopathy
Background: Central serous chorioretinopathy (CSC) is a disease that causes fluid to collect under the retina. It affects the macula, which is in the center of the retina and is needed for sharp, clear vision.
- Trial name
- NCT01585441
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Eye Institute (NEI)
Chronic Central Serous Chorioretinopathy
Microperimetric Evaluation After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
A half-dose photodynamic therapy, a relative new treatment, has been widely performed to treat central serous chorioretinopathy.
- Trial name
- NCT01434095
- Testing
- half-dose photodynamic therapy
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Surugadai Nihon University Hospital
Central Serous Chorioretinopathy, Therapy, Photodynamic
Different Doses of vPDT in the Treatment of cCSC
This is a prospective, randomized and controlled clinical trial of photodynamic therapy (PDT) for chronic central serous chorioretinopathy (CSC).
- Trial name
- NCT05390619
- Testing
- 50% dose of photodynamic therapy, 70% dose of photodynamic therapy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Central Serous Chorioretinopathy, Polypoidal Choroidal Vasculopathy
Angiographic Characteristics of CSC, PCV Patients and Thrombotic Bio-markers
Thrombotic biomarkers and angiographic characteristics were compared among the de novo patients of central serous chorioretinopathy (CSC), polypoidal choroidal vasculopathy (PCV) and the control.
- Trial name
- NCT02815176
- Testing
- Blood sampling
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Chronic Central Serous Chorioretinopathy
Photodynamic Therapy Versus Eplerenone: Treatment Trial for Chronic Central Serous Chorioretinopathy
Chronic central serous chorioretinopathy (cCSC) is a relatively frequently occurring eye disease that is often diagnosed in patients in the professionally active age range.
- Trial name
- SPECT (NCT03079141)
- Testing
- Eplerenone, Photodynamic therapy
- Where
- 3 sites in Netherlands
- Volunteers
- 107 people
- Sponsor
- Leiden University Medical Center
Central Serous Chorioretinopathy
The Safe Effective Light Dose of Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
To find the safe effective lowest light dose for photodynamic therapy (PDT). in the treatment of central serous chorioretinopathy.
- Trial name
- NCT01630863
- Testing
- Photodynamic therapy
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Yeungnam University College of Medicine
Chronic Central Serous Chorioretinopathy
Eplerenone Treatment for Chronic Central Serous Chorioretinopathy in Hungarian Population
The aim of the study is to determine the efficacy and safety of treatment with the drug eplerenone in patients with chronic central serous chorioretinopathy.
- Trial name
- NCT02462499
- Testing
- Inspra (eplerenone)
- Where
- Hungary
- Volunteers
- 28 people
- Sponsor
- Semmelweis University
Diabetic Macular Edema, Branch Retinal Vein Occlusion
Non-damaging Retinal Laser Therapy With PASCAL Laser for Macular Diseases
This trial seeks to prove the safety and efficacy of photothermal stimulation treatment to diabetic macular edema, chronic central serous retinopathy, macular edema secondary to branch retinal vein occlusion and macular…
- Conditions
- Diabetic Macular Edema, Branch Retinal Vein Occlusion, Chronic Central Serous Retinopathy, Macular Telangiectasia
- Trial name
- EPM (NCT01975103)
- Testing
- Topcon Endpoint Management
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Central Serous Chorioretinopathy
Eplerenone for the Treatment of Central Serous Chorioretinopathy
To test the effect oral eplerenone versus placebo in patients with central serious chorioretinopathy .
- Trial name
- NCT01990677
- Testing
- 25mg Eplerenone
- Where
- 10 sites in United States
- Volunteers
- 108 people
- Sponsor
- Wills Eye
Central Serous Chorioretinopathy
Choroidal Blood Flow in Acute and Chronic Central Serous Chorioretinopathy
Patients with central serous chorioretinopathy (CSC) will be monitored with laser speckle flow graphy (LSFG), swept source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA).
- Trial name
- NCT05589974
- Testing
- Verteporfin
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Chronic Central Serous Chorioretinopathy
Steroid Eye Drops in Chronic Central Serous Chorioretinopathy
In this pilot study the effect and safety of the use of steroid eye drops in chronic central serous chorioretinopathy (cCSC) will be evaluated. The study is conducted as a randomized single-blind placebo-controlled trial.
- Trial name
- PICS (NCT05633576)
- Testing
- steroid eye drops
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Chronic Central Serous Chorioretinopathy
A Pilot Study of the Treatment of Central Serous Chorioretinopathy With Ketoconazole
The purpose of this study is to determine the effect of an adrenocorticoid antagonist (ketoconazole), 600 mg per day for 4 weeks, in the treatment of patients with central serous chorioretinopathy (CSC).
- Trial name
- CSC/Keto (NCT00211393)
- Testing
- ketoconazole
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Central Serous Chorioretinopathy
Eplerenone For the Treatment of Chronic Central Serous Chorioretinopathy
The aim of the study is to determine the efficacy and safety in treating patients with chronic central serous chorioretinopathy with the drug eplerenone.
- Trial name
- NCT02153125
- Testing
- Eplerenone
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Central Serous Chorioretinopathy (CSC)
Faricimab for Chronic Central Serous Chorioretinopathy: A Randomized Sham-Controlled Trial
Dysregulation of the Angiopoietin-2 (Ang-2)/Tyrosine kinase with Immunoglobulin-like and EGF-like domains 2 (Tie-2) signaling pathway has been implicated in choroidal vascular instability and RPE dysfunction in Central serous…
- Trial name
- NCT07681167
- Testing
- Faricimab
- Volunteers
- 50 people
- Sponsor
- Singapore National Eye Centre
Chronic Central Serous Chorioretinopathy
Ranibizumab Versus Low-fluence Photodynamic Therapy in the Treatment of Chronic Central Serous Chorioretinopathy
The purpose of this study is to compare the efficacy and safety of intravitreal ranibizumab injection versus low-fluence PDT in the treatment of chronic CSC.
- Trial name
- NCT01325181
- Testing
- Verteporfin, ranibizumab
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Jang Won Heo