Clinical trials: Chronic Disease (Physical)
Chronic Physical Health Conditions
MANAGE AT WORK: Addressing the Challenge of Chronic Physical Health Conditions in the Workplace
The specific aim of the study is to evaluate the health benefits of a series of group workshops designed for workers with chronic physical health conditions.
- Trial name
- NCT01978392
- Testing
- Self-management group workshops
- Where
- 4 sites in United States
- Volunteers
- 122 people
- Sponsor
- Liberty Mutual Research Institute for Safety
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
End Stage Renal Disease, Sars-CoV2
The Impact of COVID-19 on Dialysis Users
To understand the impact of COVID-19 restrictions on the wellbeing, quality of life and physical activity of people with end-stage renal disease, currently dialysing in-centre versus at home in the UK and their experience of…
- Trial name
- NCT04422873
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Orthopedic Disorder of Spine, Placebo Effect
Clinical Predictive Effects of Mulligan Treatment in Patients With Chronic Neck Pain
The aim of the study is the measurement and comparison of two manual therapy techniques, the Mulligan´s mobilization with movement technique, and de placebo technique, both applicated in patients with subacute neck pain.
- Conditions
- Orthopedic Disorder of Spine, Placebo Effect, Disability Physical
- Trial name
- NCT05004467
- Testing
- Mobilization With Movement Technique
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Universidad Europea de Madrid
Hydrocephalus
Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device
This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow over multiple measurements performed by a study subject during headache and non-headache periods.
- Trial name
- NCT06996600
- Testing
- wireless thermal anisotropy measurement device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Rhaeos, Inc.
COPD, Chronic Musculoskeletal Pain
The Effect of a Technology-Mediated Integrated Walking and Tai Chi Intervention on Physical Function in Veterans With COPD and Chronic Musculoskeletal Pain
Persons with COPD benefit from being physically active, but they are often limited by chronic musculoskeletal pain. This project will determine whether a non-pharmacologic, integrated, technology-mediated walking and Tai Chi…
- Trial name
- WATCH for Pain (NCT05701982)
- Testing
- Every Step Counts-Tai Chi, Usual Care
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Stroke
Online Neuropilates Classes in Chronic Stroke Patients: A Pilot Randomised Feasibility Study
This study is being undertaken as part of a PhD qualification at ATU Sligo by the principal researcher Eimear Cronin. It will investigate the feasibility, safety and efficacy of a 6 week, online, remotely supervised neuropilates…
- Trial name
- NCT05739422
- Testing
- Neuropilates online exercise class, Online generalised exercise class, Unsupervised home exercise programme
- Where
- Ireland
- Volunteers
- 12 people
- Sponsor
- Institute of Technology, Sligo
Chronic Kidney Disease Requiring Chronic Dialysis
Integrating BIA and eGFR for Nutritional Status in Hemodialysis Patients
This study looks at how measurements of body composition from Bioelectrical Impedance Analysis (BIA) and estimates of kidney function (eGFR) can be applied together to better assess the health of people on hemodialysis.
- Trial name
- NCT06873880
- Where
- Estonia
- Volunteers
- 30 people
- Sponsor
- University of Tartu
Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps
The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear.
- Trial name
- NCT03975842
- Testing
- Sinonasal and otologic evaluation
- Volunteers
- 80 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Stroke, Tele-rehabilitation
Telerehab Exerbrain: Bridging Physical and Cognitive Therapy in Stroke
The goal of this clinical trial is to learn if a web-based exercise and cognitive training (physical-cognitive) program works to improve movements and brain function in adults with long-term stroke.
- Conditions
- Stroke, Tele-rehabilitation, Exercise, Motor Abilities
- Trial name
- NCT07446062
- Testing
- Web-Based Physical-Cognitive Telerehabilitation Exergaming
- Volunteers
- 52 people
- Sponsor
- Chiang Mai University
Chronic Obstructive Pulmonary Disease (COPD)
Pedometer-based Behavioural Intervention for Individuals With COPD to Stay Active After Rehabilitation
The STAR-study (STay Active after Rehabilitation) investigates in a randomized controlled trial (RCT) the additional effect of a pedometer-based behavior change intervention (BCI) during in-patient pulmonary rehabilitation (PR)…
- Trial name
- STAR (NCT02966561)
- Testing
- Pedometer-based activity promotion, Short patient education and exercise, Pulmonary rehabilitation (Standard care)
- Where
- Germany
- Volunteers
- 418 people
- Sponsor
- University of Erlangen-Nürnberg
Stroke
Comparison of the Effectiveness of an Adapted Physical Activity Program in a Dedicated Structure to a Self-program in Patients in Chronic Phase of a Stroke
This is a prospective, randomized, controlled, two parallel arms, single-blind pilot study. In this design, all included patients in the chronic phase of a stroke will receive both modes of physical activity.
- Trial name
- StrokAPA (NCT06061770)
- Testing
- Adapted physical activity program, Adapted physical activity self-program
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Liver Diseases, Liver Cirrhosis
Point-of-care Ultrasound Screening and Assessment of Chronic Liver Diseases and NASH
The main objective of the study is to determine the diagnostic performances of an ultraportable diagnostic ultrasound system for the assessment of liver fibrosis severity in patients with NASH, and to compare them to other…
- Conditions
- Liver Diseases, Liver Cirrhosis, NASH - Nonalcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease
- Trial name
- POCUS-NASH (NCT05120557)
- Testing
- Ultrasound liver assessment
- Volunteers
- 1,000 people
- Sponsor
- E-Scopics
Constipation
Colon Transit Study for Chronic Constipation Assessment and Therapy by Biofeedback With and Without TENS
One of the most challenging functional gastrointestinal illnesses (FGID) to manage is constipation, which is a widespread issue.
- Trial name
- TENS (NCT05946967)
- Testing
- Biofeedback with TENS, Biofeedback only
- Volunteers
- 50 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
PolG, Primary Mitochondrial Myopathy
Mitochondrial Video Assessment Source Material Study
Source material collection of videos to develop the Mitochondrial Video Assessment (MVA) for patients with mitochondrial myopathies.
- Trial name
- NCT06180421
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The Emmes Company, LLC
Chronic Hepatitis C
Histologic Changes and Noninvasive Assessment in Hepatitis C Patients Treated with Peginterferon Alpha-2a and Ribavirin
•The purpose of this study is to compare the performance between liver biopsy and non-invasive fibrosis assessments evaluating anti-fibrotic efficacy of peginterferon plus ribavirin in patients with hepatitis C pre- and…
- Trial name
- NCT01634919
- Testing
- chronic hepatitis C
- Where
- 2 sites in South Korea
- Volunteers
- 55 people
- Sponsor
- Seoul National University Boramae Hospital
Sleep Disorders
Efficacy and Safety Assessment of ZOlpidem (Stilnox CR) in Patients With Chronic insomNIA
Primary Objective: To evaluate the efficacy and safety of the use of Stilnox CR in Mexican patients with chronic insomnia at the prescription conditions of daily practice Secondary Objective: To evaluate the satisfaction of the…
- Trial name
- NCT01024192
- Testing
- ZOLPIDEM SL800750
- Where
- Mexico
- Volunteers
- 135 people
- Sponsor
- Sanofi
Myeloid Leukemia, Chronic
Efficacy and Safety Assessment of NIlotinib in CML Patients With Suboptimal Response on Imatinib Therapy
whether Nilotinib at the two sequential dosage forms will induce quicker and deeper response in those patients, and if FISH on PB (Peripheral blood) would be an effective way to monitor response compared to conventional…
- Trial name
- NISRI (NCT02086487)
- Testing
- Nilotinib 300 mg.
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 98 people
- Sponsor
- King Abdullah International Medical Research Center
Brain Injuries
Validating the MATADOC Against Best Practice Standard External Reference Standard
The purpose of this project is to further develop a standardized music-based measure used in music therapy with adults who have emerged from coma following profound brain injury, but are not able to demonstrate responsiveness to…
- Trial name
- MATADOC (NCT02959736)
- Testing
- MATADOC and CRS-R
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Temple University
Chronic Obstructive Pulmonary Disease
Low-dose Theophylline as Anti-inflammatory Enhancer in Severe Chronic Obstructive Pulmonary Disease
The main objective of the study is to determine the effects of low-dose oral theophylline added to combination treatment with long-acting β-agonist (LABA) and inhaled corticosteroid (ICS) in patients with severe Chronic…
- Trial name
- ASSET (NCT01599871)
- Testing
- theophylline
- Where
- 10 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Son Espases
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