Clinical trials: Chronic Disease (Physical)
Low Back Pain, Chronic
Person-Centered Lifestyle Redesign in Chronic Low Back Pain
This study is designed to examine the effects of a person-centered lifestyle intervention on pain, occupational performance, quality of life, disability, physical activity levels, and mental status in individuals with chronic low…
- Trial name
- NCT07163546
- Testing
- Lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Systemic Lupus Erythematosus, Fatigue
REACH (Restore Energy, Activity Can Help) Lupus Study
The goal of this clinical trial is to pilot test the REACH peer coaching program for fatigue in people with systemic lupus erythematosus. The main questions it aims to answer are: 1.
- Trial name
- REACH (NCT06479213)
- Testing
- REACH Peer Coaching Program, REACH Mobile Health Application
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Tufts Medical Center
COPD
A Study for the Assessment of the Benefits of a Novel Mesh Nebulizer in the Treatment of Patients With Stable COPD
Jet nebulizers have been the standard delivery system for aerosolized medications commonly prescribed to Chronic Obstructive Pulmonary Disease (COPD) patients; however, these devices are inefficient and require an external…
- Trial name
- NCT03933462
- Testing
- InnoSpire Go, Jet Nebulizer
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Philips Respironics
Chronic Kidney Disease
Effects of a Walking Intervention in Older Patients With Chronic Kidney Disease: Feasibility Study
Chronic kidney disease (CKD) affects more than 26 million individuals (13 percent) of the U.S. population, with a projected 70 percent increase by the year 2015 to over 40 million individuals.
- Trial name
- NCT02155127
- Testing
- walking
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Chronic Obstructive Pulmonary Disease
Respiratory Muscle Function, Diaphragm Thickness and Health Related Physical Fitness Parameters in Individuals
In the literature, studies evaluating respiratory muscle function, diaphragm thickness and health-related physical fitness parameters together are insufficient in individuals with chronic obstructive pulmonary disease.
- Trial name
- NCT04995510
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Abant Izzet Baysal University
Hemiplegic Cerebral Palsy, Gait Training
Effect of Biofeedback-Based Inertial Sensors Gait Training on Walking Parameters in Children With Hemiplegia
The goal of this clinical trial is to learn about the effect of biofeedback-based inertial sensors gait training on walking parameters in children with hemiplegia.
- Trial name
- NCT07683624
- Testing
- Steadys Biofeedback Gait Training System, Conventional Physical Therapy, Traditional Gait Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pediatric Obesity
Energy Intake and Energy Deficit in Obese Adolescents
The aim of the present study is to compare the effect of two weight loss interventions inducing the same energy deficit but one based on exercise and one using dietary restriction, on appetite control in obese adolescents.
- Trial name
- IDEFIX (NCT03466359)
- Testing
- DEF-EI : Energy restriction induced energy deficit, DEF-EX : Exercise induced energy deficit
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Systolic Heart Failure, Iron Deficiency
Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality
The purpose of this study is to determine whether intravenous iron supplementation using ferric carboxymaltosis (FCM) extends the time-to-first-event of heart failure hospitalisations and cardiovascular (CV) death and reduces…
- Trial name
- FAIR-HF2 (NCT03036462)
- Testing
- Iron, Saline
- Where
- 51 sites in Germany, Hungary and 5 more
- Volunteers
- 1,105 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Open-Label Assessment of the Albuterol Spiromax® Dry Powder Inhaler (DPI)
This is a prospective, open-label, multicenter Phase 3 study evaluating the performance of the Albuterol Spiromax dose counter in patients with a diagnosis of asthma and/or COPD.
- Trial name
- NCT01857323
- Testing
- Albuterol Spiromax®
- Where
- 30 sites in United States
- Volunteers
- 317 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Disease
Model for the Integral Assessment of Chronic Disease Management Supported in Information Technology and Communication.
Controlled and Randomized Clinical trial with 3 parallel groups (intervention group with a health platform NOMHADchronic, phone-based care group, usual care group) developed in the Valencia La Fe Health Department.
- Trial name
- NCT02447562
- Testing
- Platform NOMHADchronic, Phone-based care group, Usual care group
- Volunteers
- 495 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Indolent Non-Hodgkin's Lymphoma, Follicular Lymphoma
Safety and Efficacy Study of Idelalisib (GS-1101, CAL-101) in Patients With Previously Treated Low-grade Lymphoma
The primary objectives of this study is to evaluate the safety and efficacy of idelalisib (GS-1101, CAL-101) in participants with previously treated indolent non-Hodgkin lymphoma (iNHL).
- Conditions
- Indolent Non-Hodgkin's Lymphoma, Follicular Lymphoma, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma
- Trial name
- NCT01306643
- Testing
- Idelalisib
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Gilead Sciences
Cerebral Palsy, Spastic
Role Of Physical Therapy In Relieving Constipation In Children With Spastic Cerebral Palsy
This study was conducted to determine the effectiveness of Physical Therapy management in relieving constipation among Spastic Cerebral Palsy children.
- Trial name
- NCT03379038
- Testing
- Progressive Physical Therapy, Maintenance Physical Therapy
- Where
- Pakistan
- Volunteers
- 35 people
- Sponsor
- Isra University
Pulmonary Disease, Chronic Obstructive
Breathing Helium-Hyperoxia During Exercise in Patients With Chronic Obstructive Pulmonary Disease
Regular exercise can help patients with the lung disease, chronic obstructive pulmonary disease (COPD). But COPD patients have a hard time with training because of their breathing.
- Trial name
- NCT01283685
- Testing
- breathing helium-hyperoxia, breathing supplemental oxygen
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- West Park Healthcare Centre
Pelvic Venous Disorders
Venoactive Drug Treatment of Pelvic Venous Disorders
Venoactive drug (VAD) therapy is one of the most effective methods of treating chronic venous diseases (CVD). Numerous studies have proven its high efficacy in relieving symptoms of CVD, such as leg pain and swelling, leg…
- Trial name
- VENOTREAT (NCT06584799)
- Testing
- Micronized purified flavonoid fraction, Diosmin 600, Hesperidin+Diosmin combination 1000
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- Pirogov Russian National Research Medical University
Osteoarthritis, Chronic Pain Management
The Beat Pain Better Trial
The Beat Pain Better study examines strategies to increase the reach of evidence-based interventions for persons with osteoarthritis (OA) in communities that experience disparities.
- Trial name
- NCT06932887
- Testing
- Text Messaging, Motivational Messaging, Physical Activity Counseling and Self-Directed Walk with Ease
- Where
- 3 sites in United States
- Volunteers
- 346 people
- Sponsor
- University of Utah
Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy
Effect of Botulinum Toxin Type A on Motor Function in Children With Cerebral Palsy
Project Identification and Researchers Title: "Changes in functionality and quality of life when applying the botulinum toxin type A infiltration protocol in children and adolescents with cerebral palsy of the spastic hemiparesis…
- Conditions
- Cerebral Palsy (CP), Spasticity Due to Cerebral Palsy, Hemiparesis
- Trial name
- NCT07034547
- Testing
- Botulinum toxin infiltration
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Instituto Teletón Chile
Chronic Pain, Musculoskeletal Pain
Pain Neuroscience Education and Physical Exercise Program in Chronic Back Pain
This study evaluates the effects of a pain neuroscience education (PNE) and physical exercise (PE) program in patients with chronic back pain.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Back Pain
- Trial name
- NCT03654235
- Testing
- Health Education, Physical exercise, Usual care in Primary Care Physiotherapy Units
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Anemia, Chronic Kidney Disease
LEARN-6™: A Prospective, Observational Nursing Home Study
This is a prospective, multicenter, observational, hypothesis-generating study exploring mobility, Quality of Life and other physical performance measures among older, long-term stay Nursing Home residents with CKD, with versus…
- Trial name
- NCT00727571
- Testing
- Observations
- Volunteers
- 815 people, healthy volunteers welcome
- Sponsor
- Amgen
Caregivers, Dementia
Powerful Tools for Caregivers of Dementia Patients
The purpose of this study is to examine if a psycho-educational intervention for caregivers of patients with dementia will decrease caregiver burden, increase caregiver physical activity, and decrease the reporting of behavioral…
- Conditions
- Caregivers, Dementia, Alzheimer Disease
- Trial name
- PTC-dementia (NCT02697721)
- Testing
- Powerful Tools for Caregivers, Control with delayed intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
CKD Stage 3, CKD Stage 4
The Iron and Muscle Study
This is a multi-center randomized controlled trial that will examine the efficacy of IV iron supplementation when compared to placebo, with and without exercise training, on changes in patient exercise capacity.
- Conditions
- CKD Stage 3, CKD Stage 4, Iron-deficiency
- Trial name
- NCT04862715
- Testing
- Ferinject
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
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