Clinical trials: Chronic Dissection
Breastcancer, Mastectomy
Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy
A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a…
- Trial name
- PECS (NCT03023007)
- Testing
- Loco-regional anaesthesia
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Oscar Lambret
Marfan Syndrome, Aortic Dissection
Nutritional Ketosis Marfan
In this pilot clinical trial, the investigators will test whether a carefully supervised ketogenic diet can safely help people with Marfan syndrome who already have a chronic or residual aortic dissection.
- Trial name
- NCT07495267
- Testing
- Ketogenic diet
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Vertebral Artery Dissection, Cerebrovascular Accident
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology…
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Stroke
- Trial name
- NCT02667821
- Testing
- Head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Canadian Memorial Chiropractic College
Aortic Aneurysm, Thoracic, Chronic Type B Dissection
Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections
The purpose of the Feasibility study is to characterize the safety of the Valiant Mona LSA Thoracic Stent Graft System, including an assessment of the safety and effectiveness of the device acutely and at the 30 day visit in the…
- Trial name
- NCT02365467
- Testing
- Valiant Mona LSA Thoracic Stent Graft System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medtronic Cardiovascular
Aortic Aneurysm, Thoracic
Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Thoracic Aortic Aneurysms and Chronic Dissections
To ensure adequate seal of currently available stent grafts, a proximal 20 mm of healthy aorta is recommended. Extending the proximal landing zone into the arch by intentional covering of the left subclavian artery (LSA) without…
- Trial name
- MONA-LSA (NCT03738124)
- Testing
- Valiant Mona LSA Thoracic Stent Graft System
- Where
- 2 sites in France
- Sponsor
- University Hospital, Toulouse
Complex Aortic Aneurysms, Thoracoabdominal Aneurysm
Real-World Data Collection of GORE Devices Used In the Endovascular Treatment of Aortic Aneurysms Which Incorporate Visceral Arteries.
The registry population consists of patients presenting with complex aortic pathologies amenable to endovascular aortic repair that requires the incorporation of bridging stents to maintain visceral artery perfusion
- Conditions
- Complex Aortic Aneurysms, Thoracoabdominal Aneurysm, Fenestrated Endovascular Aortic Repair, Endovascular Aortic Repair
- Trial name
- ENVISION (NCT07480395)
- Where
- 26 sites in Austria, Denmark and 8 more
- Volunteers
- 400 people
- Sponsor
- W.L.Gore & Associates
Cardiovascular Diseases, Metabolic Disease
Vascular Lab Resource (VLR) Biorepository
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Disease, Peripheral Artery Disease, Carotid Disease
- Trial name
- NCT05628948
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- The Cleveland Clinic
Chronic Dissecting Aneurysm of Thoracic Aorta, Chronic Nontraumatic Dissection of Thoracic Aorta
Effect of Intraoperative Dexmedetomidine on Lung Protection Following Thoracic Aorta Surgery With Hypothermic Circulatory Arrest: a Randomized Clinical Trial
Dexmedetomidine has been known to protect the lung against inflammation and oxidative stress in diverse clinical settings. The investigators aimed to investigate the lung protective effect of dexmedetomidine in patients…
- Conditions
- Chronic Dissecting Aneurysm of Thoracic Aorta, Chronic Nontraumatic Dissection of Thoracic Aorta, Dissecting Aneurysm of the Thoracic Aorta
- Trial name
- NCT02678728
- Testing
- Dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Gangnam Severance Hospital
Critical Limb Ischemia, Peripheral Artery Disease
Safety & Feasibility Study of Tack-It Device for Vessel Dissection Repair
The study is intended to evaluate the safety and feasibility of using the Intact Vascular (Innovasc) Tack-It Endovascular Dissection Repair System (Tack Intravascular Staple System) in patients with vascular flaps in the…
- Trial name
- NCT02044003
- Testing
- Innovasc Tack Intravascular Staple System (Tack)
- Where
- 2 sites in Paraguay
- Volunteers
- 11 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Coronary Artery Disease
DISsection RE-entry Evaluation With Absorb Bioresorbable Vascular Scaffolds in CTO.
Percutaneous Coronary Intervention (PCI) is increasingly effective to treat Chronic Total Occlusion (CTO) lesions in coronary arteries.
- Trial name
- DISCRETE-CTO (NCT02936011)
- Testing
- CTO PCI using Absorb Bioresorbable Vascular Scaffolds
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Belfast Health and Social Care Trust
Resectable Pancreatic Head Neoplasm, Resectable Periampullary Neoplasm
Economisation of Whipple Resection Using an Ultrasonic Dissection Device
Including 150 randomised patient, the studies aim is to determine whether an economisation and/or improvement in terms of operating time, drainage fluid, blood loss, time of hospitalisation can be found using an ultrasonic…
- Conditions
- Resectable Pancreatic Head Neoplasm, Resectable Periampullary Neoplasm, Chronic Pancreatitis
- Trial name
- NCT01321450
- Where
- 3 sites in Germany, Greece and 1 more
- Volunteers
- 82 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Coronary Artery Disease, Coronary Occlusion
Antegrade Dissection and Re-entry Versus Retrograde Strategy in CTO PCI
The ADRENALINE trial has been designed as a multi-center, prospective randomized study to compare the procedural and periprocedural outcomes of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using…
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention
- Trial name
- ADRENALINE (NCT06878729)
- Testing
- CTO PCI using ADR strategy, CTO PCI using retrograde strategy
- Where
- 3 sites in Poland
- Volunteers
- 74 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Chronic Stanford B Type Aortic Dissection Proximal Tear
Guo's Entry Tear Repair :The First in Man Study of Endopatch System
A prospective, single-center, first in man study to evaluate the safety and efficacy of Endopatch System manufactured by Hangzhou Endonom Medtech Co., Ltd. for the Chronic Stanford B type aortic dissection proximal tear.
- Trial name
- NCT04745039
- Testing
- Endopatch System
- Where
- China
- Volunteers
- 27 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Carpal Tunnel Syndrome, Pain, Chronic
Median Nerve Hydro-dissection Using Single Injection of Hyalase as a Novel Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy, this study aims to investigate if, and to what extent hydro-dissection hyalase and saline of the median nerve could offer symptoms and clinical improvement
- Trial name
- NCT03177915
- Testing
- Hylase, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Aortic Dissection, Surgery (Cardiac)
Immune-Inflammatory Markers in Aortic Dissection
Identifying early on which patients with acute aortic dissection require closer monitoring may help with care planning. If simple, inexpensive values obtained from routine blood tests can provide additional information for…
- Conditions
- Acute Aortic Dissection, Surgery (Cardiac), Systemic Immune-inflammation Index, Postoperative Death
- Trial name
- NCT07683260
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people
- Sponsor
- Bursa City Hospital
Vestibular Migraine, Chronic Subjective Dizziness
Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness
Vestibular migraine (VM) and chronic subjective dizziness (CSD) commonly cause vertigo, unsteadiness and dizziness. Clinical investigators are studying these illnesses to understand them better.
- Trial name
- NCT01669304
- Testing
- Verapamil, Sertraline
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mayo Clinic
Chronic Dissection of Thoracic Aorta (Disorder)
Annexin Imaging in Dissection of the Descending Aorta
The relationship between the presence of a partial thrombus and aortic dilation after type B dissection has recently been reported.
- Trial name
- PAIDDA (NCT03832582)
- Testing
- Annexin
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Marfan Syndrome
Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions
Empowered Relief (ER) is a 1-session pain relief skills intervention that is delivered in-person or online by certified clinicians to groups of patients with acute or chronic pain.
- Conditions
- Chronic Pain, Marfan Syndrome, Vascular Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome
- Trial name
- NCT05980104
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Stanford University
Lymphedema, Breast Cancer
The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema
The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization…
- Trial name
- LYMPH (NCT05890677)
- Testing
- Surgical Intervention, Conservative Complex Physical Decongestion Therapy
- Where
- 36 sites in United States, Austria and 13 more
- Volunteers
- 280 people
- Sponsor
- University Hospital, Basel, Switzerland
Aortic Dissection, Aortic Aneurysm
PMCF Study in Patients With Acute or Chronic Aortic Dissection or Aortic Aneurysm Treated With E-vita OPEN NEO
The NEOS-APAC post-market clinical follow-up study is undertaken to demonstrate the safety and clinical performance of E-vita OPEN NEO in the treatment of aneurysm or dissection in the ascending aorta, aortic arch and descending…
- Trial name
- NEOS-APAC (NCT04986709)
- Testing
- Open repair
- Where
- 10 sites in Australia, Hong Kong and 4 more
- Volunteers
- 114 people
- Sponsor
- JOTEC GmbH