Clinical trials: Chronic Fatigue Symptoms
Chronic Neck Pain
Diaphragmatic Myofascial Release Added to Neck Exercises for Chronic Neck Pain
Chronic neck pain can affect daily activities and may be associated with pain, disability, fear of movement, and fatigue. Exercise is commonly used to manage chronic neck pain, but some people continue to experience symptoms…
- Trial name
- DMR-CNP (NCT07761793)
- Testing
- Neck Exercise Program, Diaphragmatic Myofascial Release and Diaphragm-Directed Manual Therapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- Abdelrahman Alghoul
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Fatigue Syndrome
ME/CFS: Activity Patterns and Autonomic Dysfunction
The purpose of this study is to identify daily activity patterns, negative life events and autonomic abnormalities that may be related to non-improvement in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Trial name
- NCT02948556
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Stony Brook University
Neoplasms, Fatigue
COMPANION: A Couple Intervention Targeting Cancer-related Fatigue
Chronic cancer-related fatigue (CCRF) is a disturbing condition that persists in up to 25% of cancer patients after completion of treatment.
- Trial name
- COMPANION (NCT05636696)
- Testing
- Samen Minder Moe (Dutch intervention name)
- Where
- 2 sites in Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mariët Hagedoorn
Hemodialysis Patient, Fatigue
The Effects of an App-based Acupressure on Alleviating Fatigue, Pruritus, and Sleep Quality Among Hemodialysis Patients
Objectives: To evaluate the effectiveness of an app-based self-guided acupressure intervention in alleviating fatigue and pruritus, and in improving sleep quality among hemodialysis patients.
- Trial name
- NCT07259369
- Testing
- app-based acupressure
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Breast Cancer, Fatigue
Nurse-Provided Care or Standard Care in Treating Patients With Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Meeting with a nurse to assess symptoms and quality of life may be more effective than standard care in treating patients with breast cancer.
- Conditions
- Breast Cancer, Fatigue, Nausea and Vomiting, Pain
- Trial name
- NCT00903305
- Testing
- medical chart review, questionnaire administration, fatigue assessment and management
- Sponsor
- City of Hope Medical Center
Fatigue, Chronic Low Back Pain
Acupressure for Fatigue and Low Back Pain
The purpose of this study is to compare two kinds of self-administered acupressure (relaxation acupressure and stimulating acupressure) to usual care for management of fatigue and pain in low back pain patients.
- Trial name
- NCT02106741
- Testing
- Relaxation acupressure, Stimulating acupressure
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Pulmonary Disease, Chronic Obstructive, Heart Failure
Neuromuscular Fatigue During Exercise in COPD-HF Overlap
Rationale. Chronic obstructive pulmonary disease (COPD) and heart failure (HF) coexist in approximately one third of patients presenting with one of these conditions.
- Trial name
- FIBOX (NCT05235685)
- Testing
- Medical air, Hyperoxia
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
CCSVI, Chronic Cerebrospinal Venous Insufficiency
Multi-center Registry for CCSVI Testing and Treatment
Patients suspected of CCSVI (chronic cerebrospinal venous insufficiency) may be tested and if appropriate treated with catheter venoplasty by an interventional radiologist in their local community who has been credentialled…
- Conditions
- CCSVI, Chronic Cerebrospinal Venous Insufficiency, Venous Malformations of CNS Draining Veins
- Trial name
- CCSVI (NCT01205633)
- Testing
- venous angioplasty
- Where
- 9 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Hubbard Foundation
Chronic Obstructive Pulmonary Disease, Foot Deformities
The Effect of Foot Deformities on Physical Activity, Fatigue Level and Quality of Life in Elderly COPD Patients
The aim of this study is to investigate the effects of changes in foot structure on physical activity level, fatigue and quality of life in COPD patients.
- Conditions
- Chronic Obstructive Pulmonary Disease, Foot Deformities, Quality of Life, Activity, Motor
- Trial name
- NCT04627935
- Testing
- The COPD Assessment Test, Navicular Drop Test, International Physical Activity Questionnaires (IPAQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
COVID Long-Haul, COVID-19
Neural and Cognitive Consequences of COVID-19 Survival
The novel coronavirus SARS-CoV-2 infection, COVID, continues to rage throughout the world with 115,000,000 confirmed cases and over 2,500,000 deaths (as of Mar 3, 2021).
- Conditions
- COVID Long-Haul, COVID-19, COVID-19 Pandemic, Brain Fog
- Trial name
- NCT06208943
- Testing
- cross-sectional MRI and EEG assessments (NO INTERVENTION)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
Chronic Fatigue Syndrome
Compound Ciwujia Granules Treat Chronic Fatigue Syndrome
To observe the improvement of Chalder scale score in patients with chronic fatigue syndrome treated by Compound Ciwujia Granules. Improvement =[(baseline score - post-treatment score)/baseline score]*100%
- Trial name
- NCT06245642
- Testing
- Compound Ciwujia Granules, Guipi Granules
- Where
- China
- Volunteers
- 235 people
- Sponsor
- Heilongjiang Quanle Pharmaceutical Co., Ltd.
Long Covid19
Cognitive Rehabilitation for People With Cognitive Covid19
Cognitive impairment is increasingly recognised as a major component of long Covid, and is estimated to be present in 25-75% of affected individuals.
- Trial name
- NCT05731570
- Testing
- Cognitive rehabilitation
- Where
- United Kingdom
- Volunteers
- 78 people
- Sponsor
- University College, London
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (ICD-10 G93.3)
Munich ME/CFS Cohort Study
The Munich cohort study MUC-CFS aims at the characterization and long-term follow-up of myalgic encephalitis/chronic fatigue syndrome (ME/CFS) in young people aged up to 25 years, as well as at the identification of…
- Trial name
- MUC-CFS (NCT06005246)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technical University of Munich
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The aim of the study is to investigate the effects of oral melatonin and zinc supplementation on core features in individuals with ME/CFS
- Trial name
- MelatoZincME (NCT05454683)
- Testing
- melatonin plus zinc, isomaltose and magnesium stearate
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Laboratorios Viñas, S.A.
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
B-cell Depletion Using the Monoclonal Anti-CD20 Antibody Rituximab in Very Severe Chronic Fatigue Syndrome
Based on pilot patient observations, and experience from the prior study KTS-1-2008, the investigators anticipate that severely affected chronic fatigue syndrome patients may benefit from B-cell depletion therapy using Rituximab…
- Trial name
- NCT01156922
- Testing
- Rituximab
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Haukeland University Hospital
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome
The hypothesis is that a subset of patients with chronic fatigue syndrome/ myalgic encephalomyelitis (CFS/ME), including also patients with no clinical response after B-cell depletion therapy using the anti-CD20 antibody…
- Trial name
- NCT01730495
- Testing
- Etanercept
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- Haukeland University Hospital
Kidney Failure, Chronic
Intradialytic Exercises During Hemodialysis
Aim. To investigate the effect of an intradialytic aerobic and resistance cycling exercise program (IARCEP) on depression, fatigue, and quality of life (QOL) in end-stage renal disease (ESRD) patients receiving haemodialysis, and…
- Trial name
- NCT02908594
- Testing
- Medical Exercise Peddler 3000, Medi-Bike, Taiwan
- Volunteers
- 76 people
- Sponsor
- Cardinal Tien Hospital
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science