Clinical trials: Chronic Fatigue Symptoms
Long-COVID, Long COVID-19
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Long COVID is a complex condition that affects approximately 1.4 million Canadians following SARS-CoV-2 infection. Fatigue is the most common symptom of Long COVID.
- Conditions
- Long-COVID, Long COVID-19, Post-COVID-19 Syndrome, Post-COVID Syndrome
- Trial name
- PREFACER (NCT06156176)
- Testing
- COVIDEx
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Lawson Research Institute of St. Joseph's
Persian Gulf Syndrome, Chronic Sinusitis
Gulf War Illness Nasal Irrigation Study
The purpose of this study is to determine whether nasal irrigation with Xylitol or saline are effective in the treatment of chronic rhinosinusitis and fatigue symptoms associated with Gulf War Illness.
- Conditions
- Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
- Trial name
- GWINIS (NCT01700725)
- Testing
- Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Multiple Sclerosis, MS, Multiple Sclerosis
Transcranial Direct Current Stimulation for Fatigue, Mood, and Cognition in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, inflammatory and disabling disease of the Cnetral Nervous System characterized by relapsing and / or progressive somatosensory, motor and vestibular clinical manifestations.
- Conditions
- Multiple Sclerosis, MS, Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Multiple Sclerosis (MS) Primary Progressive
- Trial name
- NCT07680738
- Testing
- Transcranial Direct Current Stimulation
- Where
- Mexico
- Volunteers
- 38 people
- Sponsor
- Universidad de Almeria
Myalgic Encephalomyelitis
Long-term Sequelae of COVID-19 (Myalgic Encephalomyelitis): An International Cross-Sectional Study
The term recovery from COVID-19 caused by SARS-CoV-2 is unverified because the infection leaves many symptoms due to permanent effects on multiple organs; The primary objective of this research is to understand acute and chronic…
- Trial name
- ME (NCT05059184)
- Testing
- This is an observational cross-sectional study, there is no need for intervention
- Where
- Egypt
- Volunteers
- 2,450 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Insomnia, COPD
A Behavioral Therapy for Insomnia Co-existing With COPD
Difficulty falling asleep, staying asleep or poor quality sleep (insomnia) is common in people with chronic obstructive pulmonary disease.
- Conditions
- Insomnia, COPD, Chronic Obstructive Pulmonary Disease, Fatigue
- Trial name
- NCT01973647
- Testing
- Cognitive Behavioral Therapy for Insomnia, COPD Education, Attention Control
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Illinois Chicago
Fatigue, Lymphoma
A Feasibility Study in Chronically Fatigued Cancer Survivors
Improved cancer survival has led to increased attention on long-term health and quality of life (QoL) among the survivors. Both the cancer diagnosis and intensive treatments increase the risk of late effects which may interfere…
- Trial name
- NCT04931407
- Testing
- A 12-week interdisciplinary complex intervention
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Long COVID, PASC Post Acute Sequelae of COVID 19
Brain Stimulation in Long COVID
Cognitive problems and severe fatigue are two frequently occurring symptoms in long COVID, also known as Post-Covid Condition or Post-Acute Sequelae of COVID-19 (PASC), and their causes are currently unknown.
- Conditions
- Long COVID, PASC Post Acute Sequelae of COVID 19, Post COVID-19 Condition (PCC)
- Trial name
- MALIBU (NCT07278206)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Amsterdam UMC, location VUmc
Chronic Fatigue Syndrome
Efficacy of Web-based Cognitive Behavioural Treatment for Adolescents With Chronic Fatigue Syndrome
The aim of this study is to determine the efficacy of FITNET (web-based cognitive behavioural treatment) for adolescents with Chronic Fatigue Syndrome (CFS) in The Netherlands.
- Trial name
- FitNet (NCT00893438)
- Testing
- FitNet treatment, Usual care
- Where
- 2 sites in Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Chronic Lymphocytic Leukemia
Ruxolitinib Phosphate in Reducing Fatigue in Patients With Chronic Lymphocytic Leukemia
This phase II trial studies how well ruxolitinib phosphate works in reducing fatigue in patients with chronic lymphocytic leukemia.
- Trial name
- NCT02131584
- Testing
- Questionnaire Administration, Ruxolitinib Phosphate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma, Atrial Fibrillation
The Living With a Long-Term Condition Study
Psychological distress (anxiety and depression) is common in and experienced differently by people living with long-term health conditions (LTCs).
- Conditions
- Asthma, Atrial Fibrillation, Cancer, Cerebrovascular Disorders
- Trial name
- LTC (NCT06072287)
- Testing
- Living with LTC Questionnaire
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- King's College London
Neck Pain
Isokinetic Assessment of Wrist Muscle Performance Among Medical Students With Neck Pain
PURPOSES: 1. To assess the effect of chronic non-specific neck pain on peak torque of wrist extensor and flexor muscles /body weight among Egyptian physical therapy students. 2.
- Trial name
- NCT06240611
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mohamed Mahmoud Refaey
Fatigue Syndrome, Chronic
Rehabilitation of Adolescents Living With Chronic Fatigue
Previous studies have shown that health-related quality of life (HRQoL) in adolescents living with chronic fatigue syndrome (CFS/ME) is low if compared with healthy adolescents and adolescents living with other chronic diseases.
- Trial name
- NCT04177459
- Testing
- Health promoting dialogue, standard treatment / treatment as usual
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- St. Olavs Hospital
Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic
The Effects of Relaxation Techniques on Pain, Fatigue and Kinesiophobia in Multiple Sclerosis Patients: A Three Arms Randomized Trial
Even though, current treatments including IVIG, corticosteroids, biological agents can provide positive effects on MS symptoms, MS cannot be cured completely today.
- Conditions
- Multiple Sclerosis, Relapsing-Remitting, Pain, Chronic, Fatigue Syndrome, Chronic, Kinesiophobia
- Trial name
- NCT04833673
- Testing
- PMR: Progressive Muscle Relaxation, BRT:Benson Relaxation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hacettepe University
Myasthenia Gravis
Integrating Art Therapy and Adapted Physical Activity: Toward Improved Quality of Life in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is a rare neuromuscular disease characterized by fluctuating muscle weakness and excessive fatigability. Although medical treatments have improved, MG continues to significantly impact patients' physical…
- Trial name
- APART-MG (NCT07125105)
- Testing
- Adapted Physical Activity Only, Adapted Physical Activity + Art Therapy
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Universite du Littoral Cote d'Opale
Fibromyalgia, Chronic Fatigue Syndrome
Motor Control in Chronic Fatigue Syndrome and Fibromyalgia
This project is a comprehensive study, with main focus on motor control, comparing patients with chronic fatigue syndrome / myalgic encephalopathy (CFS/ME) and/or fibromyalgia syndrome (FMS).
- Trial name
- NCT01686074
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Norwegian University of Science and Technology
Chronic Myeloproliferative Disorders, Fatigue
St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer
RATIONALE: Giving St. John's wort may be effective in relieving fatigue in patients with cancer who are undergoing chemotherapy or hormone therapy. PURPOSE: Randomized phase III trial to determine the effectiveness of St.
- Conditions
- Chronic Myeloproliferative Disorders, Fatigue, Leukemia, Lymphoma
- Trial name
- NCT00005805
- Testing
- St. John's wort
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fatigue Symptom, Fatigue
Chronic Fatigue in the Internal Medicine Outpatient Clinic: a Mixed-methods Quantitative and Qualitative Study
With this study, the investigators aim to answer the following research questions: 1. In what percentage of cases does the diagnostic process conducted during a fatigue consultation at the internal medicine outpatient clinic…
- Conditions
- Fatigue Symptom, Fatigue, Fatigue Syndrome, Chronic
- Trial name
- NCT06775262
- Where
- Netherlands
- Volunteers
- 6 people
- Sponsor
- Flevoziekenhuis
Indolent Lymphomas, Lymphoma
Combating Cancer-Related Fatigue: A Personalized Supportive Care Program
This health services study will assess a multidisciplinary intervention program directed at fatigue mitigation among patients diagnosed with indolent lymphomas.
- Conditions
- Indolent Lymphomas, Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
- Trial name
- NCT06860880
- Testing
- Exercise, Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center