Clinical trials: Chronic Health Condition
Chronic Obstructive Pulmonary Disease, Smoking Cessation
Smoking Relapse Prevention Among COPD Ex-smokers
A placebo-controlled trial to determine whether recent ex-smokers with COPD who successfully stop smoking after taking varenicline are less likely to relapse back to smoking if they continue using varenicline for a further 12…
- Trial name
- SPACE (NCT02888444)
- Testing
- Varenicline, Behavioural support
- Where
- New Zealand
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Any Condition
VOCAL BIOMARKERS FOR HEALTH MONITORING: AN OPEN LONGITUDINAL HYBRID COHORT STUDY
Voice could be considered a new vital sign in the future, being collected in routine care and complement other medical assessments. Vocal biomarkers (VB) are voice characteristics that are specific to a disease or symptom.
- Trial name
- SONAR (NCT07665229)
- Where
- Luxembourg
- Volunteers
- 3,700 people, healthy volunteers welcome
- Sponsor
- Luxembourg Institute of Health
Healthy, Postmenopausal Women
Dried Plums and Chronic Disease Markers
This study evaluates whether the consumption of California dried plums can be beneficial to your health. Previous studies using dried plums have shown beneficial effects on bone and cardiovascular health.
- Trial name
- NCT02950402
- Testing
- Two Dried Plums per day, Six Dried Plums per day
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Human Immunodeficiency Virus (HIV)
ComBaCaL HIV Prevention TwiCs
This cluster-randomized intervention is embedded in the ComBaCaL (Community-Based Chronic disease care Lesotho) cohort study (EKNZ ID AO_2022-00058, clinicaltrials.gov ID NCT05596773, Lesotho NH-REC ID 210-2022), a platform for…
- Trial name
- CoPrev (NCT07581600)
- Testing
- CoPrev model, Referral to the nearest responsible health facility
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Healthy
Exposure to the Aerobic Training Stimulus in Healthy Individuals
Fitness is an important determinant for health and influenced by using large muscles. Muscles respond to training. We want to know if adding arm exercise to leg exercise can provide a better training session for healthy…
- Trial name
- O2MVPaA (NCT06467227)
- Testing
- exercise modality
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- West Park Healthcare Centre
Pain
Evaluating the Manage My Pain App in Pain Clinics
Chronic Pain is one of the most common reasons adults seek medical care, and has been linked to restrictions in mobility and daily activities, dependence on opioids, anxiety and depression, and poor perceived health or reduced…
- Trial name
- NCT05946239
- Testing
- Manage My Pain App
- Where
- Canada
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Non-communicable Diseases (NCDs)
Community-Based Chronic Disease Care in Rural Lesotho
This ComBaCaL cohort study is to assess the impact of community-based, lay-led chronic disease screening and care interventions in rural Lesotho.
- Trial name
- ComBaCaL (NCT05596773)
- Where
- 2 sites in Lesotho, Switzerland
- Volunteers
- 17,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Heart Diseases, Type2 Diabetes
Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico
The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing…
- Conditions
- Heart Diseases, Type2 Diabetes, Hypertension, Obesity
- Trial name
- PROSPECT (NCT03794531)
- Where
- Puerto Rico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Pulmonary Disease, Chronic Obstructive, Asthma COPD
Impact of a Mobile Phone and Educational Intervention
The purpose of this pilot study was to: 1. partner with African American churches to increase awareness of COPD. 2. use a community-based approach to facilitate early detection of COPD in the church setting.
- Trial name
- NCT06878898
- Testing
- Education and mobile phone text-messaging, Education only
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Kent State University
Electronic Health Records, Chronic Disease
An RCT of an Online Training for Vulnerable Patients to Use an Online Patient Portal Website
Online patient portals are becoming ubiquitous in the US. Previous research has documented substantial usability barriers, especially among patients with limited health literacy.
- Conditions
- Electronic Health Records, Chronic Disease, Health Literacy
- Trial name
- NCT03354000
- Testing
- Take-home online training, In-person online training
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cerebral Palsy
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
This study is investigating the potential effects of a high-intensity home-exercise program among children with cerebral palsy. The program includes rhythmic movements to music that are adapted for wheelchair uses and…
- Trial name
- NCT05619211
- Testing
- Sprint-Intensity Interval Training with Telecoaching
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Lifestyle Risk Reduction, Nutrition Poor
Culturally Appropriate Nutrition Communication for Mexican American Women
A randomized controlled trial to test the effects of culturally appropriate nutrition communication for Mexican American women.
- Conditions
- Lifestyle Risk Reduction, Nutrition Poor, Chronic Disease, Obesity
- Trial name
- NCT04352530
- Testing
- Health Communication
- Where
- United States
- Volunteers
- 881 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Disparities, Community Health Workers
Philly CEAL- DECIDE+ Adaptation
Cardiovascular disease (CVD) disproportionately affects racial/ethnic minorities and underserved populations in Philadelphia. This study aims to evaluate the effectiveness of an enhanced community health worker (CHW) program that…
- Conditions
- Disparities, Community Health Workers, Cardiovascular Diseases, Social Determinants of Health (SDOH)
- Trial name
- NCT06732102
- Testing
- DECIDE, Community Health Worker Support
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV/AIDS, Chronic HIV Infection
Life Plans Intervention Study
The mass provision of HIV treatment in rural KwaZulu-Natal, South Africa has raised adult life expectancy by 18 years since 2003.
- Conditions
- HIV/AIDS, Chronic HIV Infection, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03215901
- Testing
- A Beautiful Future Video, Active Control Video
- Where
- South Africa
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Boston University
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Stress, Psychological, Depression
Evaluating an Online Acceptance and Commitment Training Program for Individuals with Chronic Health Conditions
Chronic health conditions (CHC) commonly share the challenge of impaired health-related quality of life, negatively impacting the lives of millions of people in the United States.
- Conditions
- Stress, Psychological, Depression, Well-Being, Psychological
- Trial name
- NCT06179264
- Testing
- ACT Guide for Chronic Health Conditions
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Utah State University
Chronic Obstructive Pulmonary Disease (COPD), Smoking
The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease
Cigarette smoking is the major risk factor for chronic obstructive pulmonary disease (COPD, commonly known as chronic bronchitis and emphysema).
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Smoking, Smoking Cessation, Chronic Bronchitis
- Trial name
- NCT00974064
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Social Determinants of Health
Improving Transportation Assets and the Effects on Wellness Metrics
1. Implementation of an Advanced Connected Transportation Network (ACTiN), a novel, collaborative multinetwork transportation model for small cities and rural areas. 2.
- Trial name
- ACTiN (NCT05510765)
- Testing
- Transportation service
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- John M. Salmon IV, MD
Chronic Respiratory Disease
TAKINGCARE - TAcKlING the Needs of Carers of People With Chronic respirAtoRy disEases
This study aims to: i) develop an instrument that assesses the needs of informal carers of people with chronic respiratory diseases (CRD), along diseases' trajectory, and evaluate its measurement properties; ii) identify existing…
- Trial name
- NCT06459011
- Where
- Portugal
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Chronic Obstructive Pulmonary Disease (COPD)
Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) affects up to 14 million people and is among the top five leading causes of death worldwide.
- Trial name
- COPD-LT (NCT02774226)
- Testing
- Tetrahydrobiopterin (BH4), Antioxidant Cocktail
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Augusta University