Clinical trials: Chronic Insomnia Disorder
Chronic Insomnia
Impact of Insomnia Treatment on Brain Responses During Resting-state and Cognitive Tasks
Individuals with chronic insomnia have persistent difficulty falling and staying asleep, as well as complaints of altered daytime functioning that may be associated with cognitive impairments.
- Trial name
- NCT04024787
- Testing
- Cognitive-Behavioural therapy for insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Insomnia, Insomnia Chronic
Sleep Treatment Education Program for Cancer Survivors: STEP-Together
This single-arm research study of off-treatment cancer survivors with self-reported symptoms of insomnia will test the Sleep Treatment Education Program Together (STEP-Together) intervention which is delivered as a synchronous…
- Conditions
- Insomnia, Insomnia Chronic, Survivorship
- Trial name
- NCT06736548
- Testing
- The Sleep Treatment Education Program Together (STEP-Together), Coaching Session
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Insomnia Chronic, Dementia
Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers
Over the next 30 years, more than 10 million persons living with dementia in the United States will receive care at home from an unpaid and untrained family caregiver.
- Trial name
- NiteCAPP (NCT04632628)
- Testing
- Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism Spectrum Disorder, Insomnia Chronic
Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism
Autism Spectrum Disorder (ASD) represents one of the most perplexing neurobiological disorders with a prevalence of 1 in 54 children.
- Conditions
- Autism Spectrum Disorder, Insomnia Chronic, Caregiver Burden
- Trial name
- NCT05373537
- Testing
- Cognitive behavioral therapy for Insomnia
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Insomnia
Facial Emotion Recognition in Insomnia and Emotional Regulation
Introduction Chronic insomnia is a prevalent disorder in the general population, affecting up to 20% according to French National Institute of Health and Medical Research, leading to a decline in quality of life and an increased…
- Trial name
- REFIRE (NCT06251258)
- Testing
- Facial emotion recognition test with and without eye-tracking and Cognitive Emotion Regulation. Questionnaire (CERQ)
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Sleep Disorder Insomnia Chronic
A Study of the Mechanisms by Which Mood and Sleep Disorders Interact
The main purpose of the study is to explore the mechanisms by which mood and sleep disorders interact. The exploratory aim of this study is to discover the relationship between ECG/MCG and EEG/MEG characteristics and mood and…
- Trial name
- mechanisms (NCT07495189)
- Testing
- electrocardiographic/magnetic and electroencephalographic/magnetic monitoring data, ambulatory electrocardiogram, General clinical information
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Insomnia Chronic, Inflammation
Montmorency Cherry Supplementation, Sleep, and Inflammation
This study will test the effects of Montmorency cherry supplementation on sleep outcomes and inflammatory biomarkers.
- Trial name
- NCT05700643
- Testing
- Montmorency cherry supplement, Control
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Chronic Insomnia, CBT
Mindfulness and Compassive Acceptance for Chronic Insomnia in Comparison With CBT
The main aim of this study is to test the efficacy of a Compassive Acceptance Intervention protocol (developed by the research team) for Chronic Insomnia in comparison with the standard treatment (CBT-I).
- Trial name
- ACTCOM-I (NCT05555108)
- Testing
- ACTCOM-I Intervention, Standard CBT-I Intervention
- Where
- Portugal
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
COPD, Insomnia
Progressive Relaxation for COPD: Effects on Insomnia and Satisfaction
In the life model based on the activities of living developed by nursing theorists Roper, Logan, and Tierney, sleep is identified as one of the twelve essential activities.
- Trial name
- NCT06933602
- Testing
- relaxin
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ceylan Aksoy
Chronic Low-back Pain, Insomnia
Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study
Our goal is to observational study is to determine feasibility of partial sleep restriction in individuals with CLBP+I and correlation findings with features of central sensitization.
- Conditions
- Chronic Low-back Pain, Insomnia, Sleep
- Trial name
- NCT07008924
- Testing
- No intervention is provided. We monitor natural recovery to full sleep.
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Chronic Insomnia Disorder
Changed Serum Levels of Sirtuin1 and Sirtuin3 and Their Correlations With Sleep Quality and Cognitive Function in the Patients With Chronic Insomnia Disorder
The goal of this study is to explore whether mitochondrial dysfunction exists in patients with chronic insomnia disorder. The main questions it aims to answer are : Do serum mitochondrial markers change in patients with chronic…
- Trial name
- SIRT1 SIRT3 (NCT06955299)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chaohu Hospital of Anhui Medical University
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Chronic Insomnia, Chronic Pain
Lemborexant vs Zopiclone vs Clonidine for Insomnia Treatment in Chronic Pain Patients
Prospective observational crossover study of 150 consenting adult patients who are undergoing chronic pain management. For insomnia treatment, each patient ingests prescribed doses of Lemborexant or Zopiclone or Clonidine on…
- Trial name
- NCT05618002
- Testing
- Lemborexant
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Chronic Insomnia Disorder
Study on the Therapeutic Effect and Mechanism of Transcranial Plasma Stimulation in the Treatment of Chronic Insomnia
This study is a single center study, led by Dr. Ma Qinying from the Department of Neurology at the First Hospital of Hebei Medical University.
- Trial name
- NCT06252779
- Testing
- Plasma therapy equipment, Fake therapeutic device
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qinying Ma
Chronic Pain, Chronic Insomnia
NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients
This project addresses the highly significant problem of developing effective strategies for facilitating withdrawal from opioid medications.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT05226026
- Testing
- NiteCAPP HELPS, Tapered Withdrawal
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Chronic Insomnia, Melatonin
Effect of Suanzaoren Decoction and Huanglian Wendan Decoction on Biorhythm of Insomnia Patients
The purpose of this study was to examine the impact of Chinese medicine on melatonin levels in patients with insomnia
- Conditions
- Chronic Insomnia, Melatonin, Circadian Rhythm, Suanzaoren Decoction and Huanglian Wendan
- Trial name
- NCT06467851
- Testing
- Suanzaoren Decoction and Huanglian Wenda Decoction
- Where
- 2 sites in China
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences