Clinical trials: Chronic Low Back Pain, completed
Chronic Low Back Pain (CLBP)
Virtual Reality Programme Incorporating Psychology and Physiotherapy for Chronic Low Back Pain
The main objective of this randomized controlled pilot trial is to investigate the efficacy of a 4-week multidisciplinary intervention for patients with chronic non-specific low back pain, combining a therapeutic exercise program…
- Trial name
- CLEVER-BODY (NCT06757413)
- Testing
- Enhanced Virtual reality, Active Comparator: Treatment as usual
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Cardenal Herrera University
Post-Dural Puncture Headache, Chronic Headache
Long Term Outcomes After Accidental Dural Puncture ADP Study
Post Dural Puncture Headache (PDPH) causes significant short-term disability, prevents mobilisation, affects childcare activities and results in prolonged hospital stay.
- Conditions
- Post-Dural Puncture Headache, Chronic Headache, Chronic Low Back Pain
- Trial name
- NCT03080779
- Where
- 3 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- University Hospitals, Leicester
Chronic Pain, Low Back Pain
High Level Pulsed Heat Versus Low Level Steady Heat in Subjects With Chronic Low Back Pain
This study is a double blinded randomized active placebo controlled trial in subjects with chronic low back pain. The trial compares pain relief by a device that delivered high level pulsed heat (45 °C) to pain relief delivered…
- Conditions
- Chronic Pain, Low Back Pain, Heat, Analgesia
- Trial name
- NCT04109703
- Testing
- High Level Pulsed Heat delivered by Generation 5 devices from Soovu Labs Inc., Low Level (37 degrees C) delivered by the control device Generation 5 devices from Soovu Labs Inc.
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Low Back Pain
Duragesic® (Fentanyl Transdermal System) Functionality Trial in Chronic Low Back Pain
The purpose of this study is to assess physical functionality changes over a minimum of 9 weeks in patients with non-malignant chronic low back pain who are taking short-acting opioids (narcotic pain medications) for 4 or more…
- Trial name
- NCT00237341
- Testing
- fentanyl
- Volunteers
- 358 people
- Sponsor
- PriCara, Unit of Ortho-McNeil, Inc.
Catastrophizing Pain, Pain, Somatic
The Association Between Conditioned Pain Modulation and Pain Catastrophizing in Chronic Low Back Pain
This study evaluates the potential association between pain catastrophizing thoughts and the ability to dampen pain via endogenous descending inhibition.
- Conditions
- Catastrophizing Pain, Pain, Somatic, Chronic Low Back Pain
- Trial name
- NCT03644810
- Testing
- PPT measurement, Pain catastrophizing scale, Cold Pressor Test
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Chronic Non-Specific Low Back Pain
Pilates Mat Versus Segmental Control Exercises In Patients With Chronic Non-Specific Low Back Pain
This study sought to determine the effect of Pilates exercises versus segmental control exercises on spinopelvic angles, pain intensity, and functional disability in patients with chronic non-specific low back pain.
- Trial name
- NCT06762951
- Testing
- Pilates mat exercices, Segmental control exercises, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Lower Back Pain
Post Isometric Relaxation and Core Stability Exercises in Sacroiliac Joint Dysfunction
There is growing evidence on the effects of post isometric relaxation exercises and core stability exercises on pain and disability secondary to various disorders.
- Trial name
- NCT05529602
- Testing
- conventional physical therapy, relaxation exercise
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
The Safety and Efficacy of the Buprenorphine Transdermal Delivery System in Subjects With Chronic Back Pain.
The objective of this study is to assess the safety and efficacy of the buprenorphine transdermal system (5, 10, and 20 mg) in comparison to placebo transdermal system and hydrocodone/acetaminophen in subjects with chronic back…
- Trial name
- NCT00315887
- Testing
- Buprenorphine transdermal delivery system
- Where
- 22 sites in United States
- Volunteers
- 250 people
- Sponsor
- Purdue Pharma LP
Pain, Chronic Pain
Effect of Pulse Width With Spinal Cord Stimulation
The primary objective of this study is to assess the effects of varying pulse width in suprathreshold dorsal column stimulation in patients with low back pain.
- Conditions
- Pain, Chronic Pain, Back Pain
- Trial name
- NCT00399516
- Testing
- Precision
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Boston Scientific Corporation
Chronic Low Back Pain
Efficacy and Safety of EN3324 (Axomadol) in Subjects With Chronic Low Back Pain
The purpose of this study is to determine the efficacy and safety of EN3324 (axomadol) in subjects with moderate to severe chronic low back pain
- Trial name
- CLBP (NCT01043263)
- Testing
- EN3324 (axomadol)
- Where
- 59 sites in United States
- Volunteers
- 236 people
- Sponsor
- Grünenthal GmbH
Back Pain
Effects of Rhythmic Stabilization and Mckenzie Techniques on Non Specific Chronic Low Back Pain
Non-specific low back pain is defined as low back pain not attributable to an identifiable, known specific pathology. Non-specific low back pain accounts for over 90% of patients presenting to primary care and these are the majority…
- Trial name
- NCT05207605
- Testing
- Rhythmic Stabilization (RS), McKenzie technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Chronic Low-back Pain
Efficacy and Safety in the Combination of Celecoxib / Pregabalin / Vitamin B for Low Back Chronic Pain
Phase III longitudinal, multicenter, randomized, double-blind clinical trial. The aim of this study is to evaluate the efficacy and security of the drug combination of Celecoxib / Pregabalin / Vitamin B versus Celecoxib + Vitamin…
- Trial name
- NCT06516094
- Testing
- Celecoxib+Pregabalin+Vitamin B fixed dose, Celecoxib + Vitamin B fixed dose, Pregabalin + Vitamin B fixed dose
- Where
- Mexico
- Volunteers
- 192 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Chronic Low-back Pain, Low Back Pain
Using Non-Weightbearing Stationary Elliptical Machines for Patients with Chronic Low Back Pain
The goal of this clinical trial is to assess the effect of non-weightbearing stationary ellipticals (Cubii, Fitness Cubed, Inc.) on patient well-being with chronic lower back pain (CLBP).
- Trial name
- Cubii (NCT05724160)
- Testing
- Using sitting ellipticals, Physiotherapy Protocol
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Massachusetts General Hospital
Low Back Pain, Inflammation
Acute Effects of High Intensity Training on Pain Processing and Inflammation in Chronic Low Back Pain.
A multitude of exercise therapy modalities are effective in improving daily physical function and relieving pain in various forms of chronic musculoskeletal pain (CMP) such as chronic neck pain, osteoarthritis, fibromyalgia, and…
- Trial name
- NCT04902196
- Testing
- high intensity cardiorespiratory exercise protocol, moderate intensity cardiorespiratory exercise protocol
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Low Back Pain
Mediators and Moderators of Pain Neuroscience Education on Disability of Patients With Nonspecific Chronic Low Back Pain
The purpose of this observational study is understanding the underlying mechanisms of how PNE impacts disability in chronic low back pain patients (CLBP).
- Trial name
- NCT04399473
- Testing
- Pain Neuroscience Education (PNE)
- Where
- 6 sites in Saudi Arabia
- Volunteers
- 249 people
- Sponsor
- University of Utah
Chronic Non-specific Low Back Pain
Efficacy and Safety of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain
Analysis of the efficacy, maintenance of efficacy, long-term safety, and investigation of the potential for dependence and abuse and the effect of abrupt drug withdrawal of VER-01 in the treatment of patients with chronic…
- Trial name
- NCT04940741
- Testing
- VER-01
- Where
- Germany
- Volunteers
- 820 people
- Sponsor
- Vertanical GmbH
Low Back Pain
Specific or Non-Specific Manipulation for Patients With Back Pain
We aim to evaluate the long-term effects of 10 sessions of spinal manipulative therapy applied in a vertebral region-specific or region nonspecific level immediately after treatment and 3 and 6 months after randomization.
- Trial name
- NCT02883634
- Testing
- Specific manipulation, Non-specific manipulation
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Back Pain
Comparison of Static & Dynamic Back Extensor Endurance Exercises in LBP
This study will help to find the effects of static and dynamic back extensors exercises for chronic low back pain.
- Trial name
- NCT04559477
- Testing
- Static extension endurance exercise, Dynamic extension endurance exercise
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Non-specific Chronic Low Back Pain
Manual Therapy Plus Pain Neuroscience Education With Integrated Motivational Interviewing in Individuals With Non-Specific Chronic Low Back Pain
Non-specific chronic low back pain (NSCLBP) is characterized by persistent back pain that lasts longer than 12 weeks. This clinical trial aims to examine the short-term and long-term effects of adding Pain Neuroscience Education…
- Trial name
- NCT05928975
- Testing
- MT+ PNE with MI, MT, Control
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- International Hellenic University
Chronic Low-back Pain (cLBP)
Visual Feedback Manipulation in Virtual Reality Alters Extension-evoked Pain Perception in Chronic LBP
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR).
- Trial name
- CLEVER BODY (NCT06750900)
- Testing
- NORMAL CONDITION, UNDERSTATED CONDITION, OVERSTATED CONDITION
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
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