Clinical trials: Chronic Low Back Pain, completed
Chronic Osteoarthritis Pain, Chronic Low Back Pain
Study of PIPE-791 for Subjects With Chronic Osteoarthritis Pain or Chronic Low Back Pain
The primary goal of this clinical trial is to learn if PIPE-791 is safe and well-tolerated in adults with chronic osteoarthritis pain (COAP) or chronic low back pain (CLBP).
- Trial name
- NCT06810245
- Testing
- PIPE-791
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- Contineum Therapeutics
Low Back Pain
Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain
Low back pain (LBP) encompasses heterogeneous patients unlikely to respond to a unique treatment. Identifying sub-groups of low back pain may help to improve treatment outcomes.
- Trial name
- NCT03464877
- Testing
- Multi-station full-body supervised exercise program
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Marc Perron
Low Back Pain
True Functional Restoration and Analgesia in Non-Radicular Low Back Pain
You are asked to take part in this study because you have chronic, non-radicular low back pain. This study is done to investigate the pain relieving effects of the study drug Exalgo (Hydromorphone ER) for people who experience…
- Trial name
- Covidien (NCT01455519)
- Testing
- Hydromorphone ER, Sugar pill
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Shirley Ryan AbilityLab
Opioid Use, Low Back Pain
Impact of DuoTherm on Opioid Use and Low Back Pain
Evaluate the difference in opioid use, pain intensity and pain interference in patients with moderate to severe low back pain using DuoTherm multimodal harmonic mechanical stimulation (M-Stim) unit compared to Transcutaneous…
- Trial name
- NCT04491175
- Testing
- M-Stim, TENS
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Chronic Low Back Pain, Leg Pain
MIS MiLIF Versus Open
This study is being undertaken to compare the clinical outcomes of patients that have unilateral posterolateral lumbar interbody fusion using a traditional open approach versus the MiLIF procedure based on the MiCOR Precision…
- Trial name
- NCT00792129
- Testing
- The Atavi System
- Where
- 9 sites in United States
- Volunteers
- 113 people
- Sponsor
- Zimmer Biomet
Chronic Low Back Pain
Patient Engagement Via Crowdsourcing
The study aims to advance pain research by exploring feasibility of crowdsourcing patient pain data via Amazon Mechanical Turk, the largest and most studied crowdsourcing platform in the U.S.
- Trial name
- PECS (NCT03264521)
- Testing
- Surveys
- Where
- United States
- Volunteers
- 8,193 people, healthy volunteers welcome
- Sponsor
- RAND
Low Back Pain
Comparison of Physiotherapy Methods Applied To The Diaphragm In Chronic Low Back Pain
The aim of this study was to compare the effects of conservative treatment with diaphragmatic myofascial release (DMR) and abdominal hypopressive exercise (AHE) technique added to conservative treatment in chronic low back pain.
- Trial name
- NCT07022132
- Testing
- Diaphragmatic myofascial release (DMR), Abdominal hypopressive exercise (AHE), Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Medipol University
Non-specific Low Back Pain
The Effects of MLS LASER Therapy in Patients With Chronic Nonspecific Low Back Pain
Non-specific cronic low back pain is very common condition affecting 80-85% of adults. The most common therapies for low back pain are: patient education, excercise and physical therapy.
- Trial name
- MLSLASERlumb (NCT05870826)
- Testing
- Multiwave locked system laser therapy
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Depression, Chronic Disease (Diabetes/Low Back Pain)
Efficacy of a Blended Low Intensity Internet-delivered Psychological Program in Patients With Multimorbidity in Primary Care.
The aim of this study is to assess the efficacy in Primary Care (PC) of a low intensity psychological intervention applied using Information and communication technologies (ICTs) for the treatment of multimorbidity in PC…
- Trial name
- NCT03426709
- Testing
- Low intensity Internet-delivered psychotherapy
- Where
- 4 sites in Spain
- Volunteers
- 196 people
- Sponsor
- Javier Garcia Campayo
Degenerative Disc Disease
Comparison of IDD Therapy and Non-surgical Treatment for Low Back Pain Caused by Degenerative Disc Disease
This study is looking at a new machine called the Accu-Spina which administers internal disc decompression by following a computer program.
- Trial name
- NCT00165893
- Testing
- Accu-Spina Device/IDD therapy, Physical Therapy
- Volunteers
- 50 people
- Sponsor
- Emory University
Low Back Pain
Stabilization Exercises Alone vs Stabilization Exercises Plus Neuromuscular Electrical Stimulation in People With Chronic Low Back Pain
The purpose of this study is to investigate the feasibility of applying neuromuscular electrical stimulation on the lumbar spine, to report how tolerable the intervention is, and whether the electrical stimulation improve pain…
- Trial name
- NCT02864732
- Testing
- Rehabilitation exercises, Electrical Stimulation
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Low Back Pain, Chronic Pain
Optimize Low Back Pain
The objective of this study is to improve health care for patients with chronic LBP and increase the likelihood that patients obtain outcomes that matter most to them.
- Trial name
- OPTIMIZE (NCT03859713)
- Testing
- Physical Therapy, Cognitive Behavioral Therapy, Mindfulness
- Where
- 3 sites in United States
- Volunteers
- 749 people
- Sponsor
- University of Utah
Low Back Pain
Instrumental Soft Tissue Mobilization in Patients With Low Back Pain
Low back pain is caused by strain of the ligaments or muscles around the vertebral column or a musculoskeletal system formed due to compression of the nerves coming out of the spinal cord is a system nuisance.The process that…
- Trial name
- NCT05840380
- Testing
- instrumental soft tissue mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Chronic Low-back Pain, Chronic Non-specific Low Back Pain
Cupping Therapy in Chronic Nonspecific Low Back Pain
Chronic non-specific low back pain is a common condition that can cause disability, physical and psychological impairment, limitations in daily activities, and participation restrictions.
- Conditions
- Chronic Low-back Pain, Chronic Non-specific Low Back Pain, Low Back Pain, Cupping Therapy
- Trial name
- NCT06193603
- Testing
- True dry cupping therapy
- Where
- Iran
- Volunteers
- 48 people
- Sponsor
- Iran University of Medical Sciences
Chronic Low-back Pain
A Study Protocol Comparing a Home Rehabilitation Program Versus e-Health Program in Low Back Pain
The aim of this randomized controlled trial is to evaluate the feasibility and effectiveness of providing an e-Health rehabilitation program through a web platform performing electroanalgesia and an exercise program following the…
- Trial name
- NCT04283370
- Testing
- Home Rehabilitation Program, e-Health program
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad de Almeria
Chronic Pain
Neurophysiological Basis of Rehabilitation in Complex Regional Pain Syndrome, Type I and Chronic Low Back Pain
Complex Regional Pain syndrome Type I (CRPS-I) is a chronic progressive disease. Patients experience dramatic decline of overall well-being, despite the absence of any apparent physical cause.
- Trial name
- BrainEXPain (NCT02347579)
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Low Back Pain, Obesity
Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain
The purpose of this study is to determine if a 4 month resistance exercise program reduces the severity of low back pain, pain-related fear avoidance and improves mobility compared to standard care.
- Trial name
- NCT01250262
- Testing
- normal medical care and follow up, Isolated Lumbar Resistance Exercise Program, Total Body Resistance Exercise Program
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Florida
Low Back Pain
Kinesio Taping on Chronic Nonspecific Low Back Pain
This study propose analyze the effects of Kinesio Taping® in chronic nonspecific low back pain. All the subjects will be submitted to an evaluation of the painful sensation, functional performance, trunk range of motion and…
- Trial name
- NCT02550457
- Testing
- Functional elastic tape tensioned, Functional elastic tape non-tensioned, Rigid Tape
- Where
- Brazil
- Volunteers
- 108 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Low Back Pain
Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study
The purpose of this study is to assess the safety of the Biostat Disc Augmentation System for the treatment of chronic low-back (lumbar) pain due to symptomatic internal disc disruptions (IDD) and to obtain preliminary efficacy…
- Trial name
- NCT00693784
- Testing
- Biostat® Disc Augmentation System
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Spinal Restoration, Inc.
Chronic Low Back Pain (CLBP), Chronic Neck Pain
Comparative Analysis of Heart Rate Variability in Patients with Cervical Pain, Lumbar Pain, and Healthy Controls
This is a cross-sectional study designed to evaluate potential differences in heart rate variability (HRV) indices based on the affected body region (cervical vs lumbar) in individuals with chronic pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Neck Pain, Heart Rate Variability, Autonomic Nervous System Dysfunction
- Trial name
- NCT06890793
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
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