Clinical trials: Chronic Low Back Pain, completed
Pain, Acute, Pain, Chronic
Changes in Affective Pain Processing in Human Volunteers
The experience of pain is more than the conscious perception of nociceptive signals. Emotional and motivational aspects accompany pain, leading to its aversiveness and motivation for avoidance.
- Conditions
- Pain, Acute, Pain, Chronic, Low Back Pain
- Trial name
- NCT04280796
- Testing
- psychophysical tasks, cognitive task
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- susanne becker
Chronic Low Back Pain (CLBP)
Brain and Gene Expression Responses to Exercise in Chronic Back Pain
This study is registered retrospectively for transparency. This mechanistic randomized controlled trial examined whether a 14-week supervised physical exercise training program reduces chronic low back pain (CLBP) by modulating…
- Trial name
- CLBPE (NCT07480460)
- Testing
- Supervised physical exercise training
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- McGill University
Low Back Pain
Sensory Effects of Oral Opioid Treatment in Patients With Chronic Low Back Pain
Chronic low back pain (CLBP) afflicts up to 50 million U.S. adults and is a primary cause of disability and reduced quality of life.
- Trial name
- NCT02824276
- Testing
- Oxycodone or morphine sulfate immediate release (MSIR)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brigham and Women's Hospital
Chronic Low Back Pain
Trunk Muscle Training and Neuromuscular Electrical Stimulation to Improve Function in Older Adults With Chronic Low Back Pain
Low back pain (LBP) is the most frequently reported musculoskeletal problem and third most frequently reported symptom of any kind in people over the age of 75.
- Trial name
- NCT01632618
- Testing
- Trunk Muscle Training+NMES, Passive control intervention
- Volunteers
- 64 people
- Sponsor
- University of Delaware
Facet Joint Pain; Low Back Pain
Sidekick vs Conventional Cannula in Lumbar Medial Branch Radiofrequency Ablation
Lumbar facet joint-mediated chronic low back pain is a common cause of disability. Radiofrequency ablation (RFA) of the lumbar medial branches is an established interventional pain treatment.
- Trial name
- SIDE-RFA (NCT07475689)
- Testing
- Lumbar Medial Branch Radiofrequency Ablation, Triamcinolone (20 g), bupivacain 0.5% 2ml
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Chronic Pain, Neuropathic Low Back Pain
Effects of CFT in Individuals With CNLBP
This research aims to deepen the understanding of the interplay between chronic neuropathic low back pain and its effects on physical health, mental well-being, and overall quality of life.
- Trial name
- NCT05351008
- Testing
- Cognitive Functional Therapy, Exercise program:
- Where
- Greece
- Volunteers
- 52 people
- Sponsor
- International Hellenic University
Chronic Non-specific Low Back Pain
McGill Stabilization Exercises VS Proprioceptive Neuromuscular Facilitation Technique in Chronic Non-specific LBP
Non-specific chronic low back pain (NS-CLBP) is defined as lumber pain persisting for longer than three months, in absence of a suspected pathology or any specific cause.
- Trial name
- NCT05915715
- Testing
- McGill stabilization exercise, Proprioceptive neuromuscular facilitation technique
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Peripheral Neuropathic Pain, Radiculopathy
Burst Spinal Cord Stimulation for Neuropathic Pain.
This study will evaluate the effect of Burst spinal cord stimulation (SCS) in the treatment of painful radiculopathy in lower extremity(ies) with or without lower back pain.
- Conditions
- Peripheral Neuropathic Pain, Radiculopathy, Lower Back Pain
- Trial name
- NCT03733886
- Testing
- Burst SCS (Abbott Proclaim IPG and single lead Abbott Octrode at level Th9/10)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 10 people
- Sponsor
- Oslo University Hospital
Musculoskeletal Disorder, Rotator Cuff Tendinitis
Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality
This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy…
- Conditions
- Musculoskeletal Disorder, Rotator Cuff Tendinitis, Chronic Low Back Pain, Carpal Tunnel Syndrome
- Trial name
- Schem-TMS (NCT03567109)
- Testing
- hand laterality judgment task
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Angers
Chronic Low Back Pain
Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial
This study is designed to examine brain properties for placebo response in chronic back pain patients. The investigators have preliminary data indicating that, in blinded clinical trial studies with neutral instructions regarding…
- Trial name
- NCT02013427
- Testing
- Naproxen, Omeprazole
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Northwestern University
Chronic Low Back Pain (Non-specific, Uncomplicated)
Effectiveness of Functional Taping, Manual Therapy and Stereodynamic Interference Current
This study aimed to compare the effects of functional taping, manual therapy, and stereodynamic interference current applications on pain, functional capacity, sleep quality, and kinesiophobia in individuals with chronic low back…
- Trial name
- NCT06961903
- Testing
- physiotherapy programme, Functional Taping, Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Uskudar University
Low Back Pain
The Spinopelvic Parameters, Body Mass Index and Waist Circumference in Patientd Chronic Non-specific Low Back Pain
This pilot study aims at styding the correlations between body mass index, waist circumference and the potential for positional adaptation of the pelvis to support overweight or obesity
- Trial name
- NCT05771493
- Testing
- Measurement of baseline characteristics
- Where
- Belgium
- Volunteers
- 272 people
- Sponsor
- AZ Nikolaas
Back Disorder
Effects of Patient Education Manual in Patient With Chronic Low Back Pain
It was a randomized clinical trial conducted to determine the effects of patient education manual on pain, range of motion and function in patient with chronic low back pain at Salamat hospital Satellite Town Gujranwala in…
- Trial name
- NCT04600843
- Testing
- Physical therapy with Patient education, Physical Therapy without patient Education
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Low Back Pain, Chronic Pain
Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults
The long-range goal is to reduce suffering and establish alternative options for older adults experiencing pain. This is a randomized controlled study examining the effect of music on pain management in older adults.
- Conditions
- Low Back Pain, Chronic Pain, Sleep, Aging
- Trial name
- NCT04785963
- Testing
- Music with Suggestion, Pain Information, Music
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor University
Chronic Low Back Pain, Lumbar Radiculopathy
Low-Dose Naltrexone and Acetaminophen Combination in the Treatment of Chronic Low Back Pain (ANODYNE-4)
Treatment of chronic low-back pain with low-dose naltrexone and acetaminophen combination: a small, randomized, double-Blind, and placebo-controlled clinical trial with an open-label extension for none-responders
- Trial name
- NCT03201393
- Testing
- Low-dose naltrexone and acetaminophen combination
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Allodynic Therapeutics, Inc
Chronic Low-back Pain
MIC of Turkish Pain-related Psychological Measures
This study evaluates the responsiveness and minimal important change of the Turkish versions of the Fear-Avoidance Beliefs Questionnaire, Tampa Scale for Kinesiophobia, and Pain Catastrophizing Scale in adults with chronic…
- Trial name
- NCT06271447
- Testing
- Standardized Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Acibadem University
Lumbar Central Spinal Stenosis, Restless Legs Syndrome
Epidural Steroid Injection for Restless Legs Symptoms in Lumbar Stenosis
Lumbar central spinal stenosis (LCSS) is a common degenerative spinal disorder characterized by narrowing of the spinal canal, resulting in chronic low back pain, leg pain, and neurogenic claudication.
- Trial name
- NCT07637643
- Testing
- Lumbar Interlaminar Epidural Steroid Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Low Back Pain
Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets
This is a 6-month, nonrandomized, open-label extension study to assess the long-term safety of hydrocodone bitartrate extended-release (ER) tablets in patients with moderate to severe chronic low back pain who require continuous…
- Trial name
- NCT01922739
- Testing
- Hydrocodone ER
- Where
- 61 sites in United States
- Volunteers
- 182 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Low Back Pain (CLBP)
Validity and Reliability of Face-to-Face and Tele-Assessment of Core Stability and Functional Capacity
This study aims to compare the validity and reliability of core stability and functional capacity measurements when performed face-to-face and through tele-assessment in individuals with chronic low back pain.
- Trial name
- NCT07256873
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istinye University
Chronic Nonspecific Low Back Pain
Study Comparing Cortical Function and Dysfunction Tests in Low Back Pain
The purpose of this study is to explore the cortical regulation of the paraspinal muscles in chronic low back pain. These (possible) changes in regulatory mechanisms are being compared to other motor control tests in order to…
- Trial name
- NCT00924495
- Testing
- transcranial magnetic stimulation
- Where
- Finland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
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