Clinical trials: Chronic Low Back Pain, completed
Low Back Pain
Predictors of Self-management in Patients With Chronic Low Back Pain
Supported self-management (SM) is one of the key recommendations in management of chronic low back pain (CLBP). SM programmes for patients with CLBP have failed to show clinically meaningful improvement in pain and disability…
- Trial name
- NCT02636777
- Testing
- no intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- University of Nottingham
Chronic Low Back Pain
Effects of OMT on Interoception
Recent evidence suggested that the anterior insula cortex seems to be the main site of interoception. Several studies showed an association between change in insula function and interoception, bodily perception and consciousness…
- Trial name
- NCT02464475
- Testing
- osteopathic manipulative treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Come Collaboration
Low Back Pain
Open-Label, Extension Study to Evaluate the Safety of Hydrocodone Bitartrate Extended-Release Tablets
This is a 6-month, nonrandomized, open-label extension study to assess the long-term safety of hydrocodone bitartrate extended-release (ER) tablets in patients with moderate to severe chronic low back pain who require continuous…
- Trial name
- NCT01922739
- Testing
- Hydrocodone ER
- Where
- 61 sites in United States
- Volunteers
- 182 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Chronic Low-back Pain
TENS Reduces Movement-Evoked Pain in People With CLBP
In this cross-over study 25 patients with chronic low back pain (CLBP) were tested for pain relief in 2 conditions: while using the Transcutaneous Electrical Nerve Stimulation (TENS) application and without using it.
- Trial name
- NCT04090814
- Testing
- HeatTens (HV-F311-E)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain
The Effects of Telerehabilitation and Supervised Stabilization Exercises in Individuals With Nonspecific Chronic Low Back Pain
This study aims to investigate the effects of telerehabilitation and supervised stabilization exercises on pain, functionality, kinesophobia and quality of life in individuals with non-specific chronic low back pain.
- Trial name
- NCT04759430
- Testing
- Supervised Group, Telerehabilitation group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Bahçeşehir University
Low Back Pain
Auricular Vagus Nerve Stimulation for Chronic Pain
This proposal aims to investigate the treatment effect and underlying mechanism of transcutaneous acupuncture stimulation on chronic low back pain.
- Trial name
- NCT03959111
- Testing
- Stimulation at Location 1, Stimulation at Location 2
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Spondyloarthropathy
Rehabilitative Therapy and Pridinol in Patients With Lumbar Spondylarthrosis and Chronic Low Back Pain
Spondyloarthrosis is a degenerative disease involving the intervertebral disc, vertebral bodies, and adjacent soft tissues. Treatment aims to slow disease progression and manage symptoms through an interdisciplinary approach.It…
- Trial name
- NCT06252064
- Testing
- Rehabilitation + Drug therapy, Rehabilitation, Drug therapy
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- University of Palermo
Low Back Pain
Genetic Predisposition for Chronic Non-specific Low Back Pain
Patients with inflammatory back pain were shown to differ from healthy controls in genotype of the Angiotensin-converting enzyme (ACE), which regulates vasoconstriction/-dilatation.
- Trial name
- Backgene (NCT02955407)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Chronic Refractory Low Back and Leg Pain
Prospective Randomized Feasibility Study Comparing Manual vs. Automatic Position-Adaptive Spinal Cord Stimulation With Surgical Leads
The main purpose of this study is to establish the extent that chronic pain patients implanted with surgical, laminectomy-type, leads experience position-related variation in spinal cord stimulation therapy and to investigate the…
- Trial name
- RestoreSensor (NCT01874899)
- Testing
- RestoreSensor Neurostimulation
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Justin Parker Neurological Institute
Chronic Low-back Pain
Music-based Treatments and Pain: Underlying Mechanisms and the Beneficial Effects of Music-Based Treatments
The purpose of this study is to understand the mechanisms that underlie the beneficial effects of music-based treatments in individuals with moderate to severe chronic low back pain
- Trial name
- NCT05578781
- Testing
- Music Therapy, Music Medicine, Control group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Washington
Low Back Pain
Effect of Interferential l Therapy on Low Back Pain
Background: Chronic non-specific low back pain is defined as unknown mechanical musculoskeletal pain lasting more than 3 months.
- Trial name
- [PTREC] (NCT03961477)
- Testing
- Interferential therapy
- Where
- 2 sites in Egypt
- Volunteers
- 61 people
- Sponsor
- Ahlia University
Chronic Low Back Pain
Physical CAM Therapies for Chronic Low Back Pain
This is a pilot randomized trial intended to evaluate the effectiveness of acupuncture, chiropractic and massage for chronic back pain in older and younger adults.
- Trial name
- NCT00065975
- Testing
- massage therapy, chiropractic, acupuncture
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Chronic Low Back Pain (CLBP)
Voice-Derived Acoustic Features and Pain Intensity in Chronic Low Back Pain
This observational study investigated whether characteristics of a person's voice are associated with pain intensity in adults with chronic low back pain and whether voice recordings can help predict individual pain levels.
- Trial name
- NCT07078019
- Testing
- Voice Recording Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- nurmuhammet tas
Cannabis, Low Back Pain
Trial of Dronabinol and Vaporized Cannabis in Chronic Low Back Pain
This study will involve treating low back pain associated with nerve injury with oral delta-9-tetrahydrocannabinol (Δ9-THC) or whole plant cannabis for eight weeks.
- Conditions
- Cannabis, Low Back Pain, Neuropathic Pain
- Trial name
- NCT02460692
- Testing
- dronabinol, Vaporized Cannabis 3.7% THC/5.6% CBD
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of California, San Diego
Low Back Pain
Long Term Safety and Efficacy Study of Tanezumab in Japanese Adult Subjects With Chronic Low Back Pain
This study will investigate the long-term safety and efficacy of a fixed dose of tanezumab 5 mg and 10 mg administered subcutaneously (SC) seven times at 8 week intervals.
- Trial name
- TANGO (NCT02725411)
- Testing
- Celecoxib, Tanezumab 5 mg, Tanezumab 10 mg
- Where
- 55 sites in Japan
- Volunteers
- 277 people
- Sponsor
- Pfizer
Low Back Pain
Efficacy and Safety of Lymphdiaral Basistropfen (HDC) in the Treatment of Chronic Low-back Pain
To evaluate superiority of HDC in comparison to placebo in the treatment of chronic low-back pain in relation to pain, functional impairment, quality of life, and state of health during a 15-week treatment period.
- Trial name
- 144 (NCT01049373)
- Testing
- HDC
- Where
- Germany
- Volunteers
- 221 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Chronic Low Back Pain, Non Specific Low Back Pain
Which Exercise for Low Back Pain: A Validation Study
Dr. Macedo and others involved in the proposed research recently conducted a study that investigated whether simple clinical characteristics could identify patients who benefit more from either motor control exercises or graded…
- Trial name
- NCT03327753
- Testing
- Motor control exercises, Graded activity
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Chronic Low-back Pain, Hip Impairments
Manual Therapy and Strengthening for the Hip in Older Adults With Chronic Low Back Pain
Older adults with chronic low back pain (LBP) are at a greater risk for disability, loss of independence, and lower quality of life.
- Conditions
- Chronic Low-back Pain, Hip Impairments, Hip-spine Syndrome, Osteoarthritis
- Trial name
- MASH (NCT04009837)
- Testing
- Hip-focused rehabilitation intervention, Spine-focused rehabilitation intervention
- Where
- 3 sites in United States
- Volunteers
- 184 people
- Sponsor
- University of Delaware
Chronic Low-back Pain, Muscle Atrophy
Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain
The goal of this pilot randomized controlled trial is to compare the effects of aquatic therapy versus standard care on paraspinal and gluteal morphology and function in individuals with chronic low back pain.The main questions…
- Conditions
- Chronic Low-back Pain, Muscle Atrophy, Diagnostic Imaging, Exercise Therapy
- Trial name
- NCT05823857
- Testing
- Aquatic Therapy, Standard Care
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Concordia University, Montreal
Chronic Pain, Lumbar Pain Syndrome
BioWave High-frequency Neurostimulation Versus TENS for the Treatment of Chronic Low Back Pain
This will be a multicenter randomized crossover clinical trial comparing the therapeutic efficacy of BioWave therapy versus TENS for the management of chronic low back pain.
- Conditions
- Chronic Pain, Lumbar Pain Syndrome, Low Back Pain
- Trial name
- BioWave (NCT05511181)
- Testing
- BioWave, TENS
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- BioWave Corporation
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