Clinical trials: Chronic Low-back Pain (cLBP)
Low Back Pain, Paraspinal Muscle
Sodium Aescinate for the Treatment of Low Back Pain (LBP) in Adults
The goal of this clinical trial is to assess the clinical efficacy and safety of sodium aescinate in treating low back pain (LBP) in adult participants.
- Conditions
- Low Back Pain, Paraspinal Muscle, CLBP - Chronic Low Back Pain, Non-specific Chronic Low Back Pain
- Trial name
- NCT07339631
- Testing
- Sodium Aescinate Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xijing Hospital
Sleep Disturbance, Chronic Low-back Pain
Trans Cranial Direct Current Stimulation Along With Craniosacral Therapy on Sleep Disturbances in Patients With Chronic Low Back Pain
Sleep problems in patients with CLBP are a very common complication and is the most neglected part of the management. Though previous literature suggested that sleep problems need to be managed in patients with CLBP, no physical…
- Trial name
- NCT03976232
- Testing
- Trans cranial Direct Current Stimulation (tDCS), Craniosacral therapy (CST), tDCS+ CST
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Low Back Pain, Chronic Low-back Pain (cLBP)
The Relationship Between Disability, Fear Avoidance Beliefs, Physical Performance and Quality of Life in Chronic Low Back Pain
The aim of this study was to determine the multidimensional profile of individuals with chronic low back pain (CLBP) and to determine the relationship between disability and fear avoidance beliefs, physical performance and…
- Trial name
- NCT06869668
- Testing
- Correlation
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul Arel University
Chronic Low Back Pain (CLBP)
Acute Effect of Isometric Excercise on Pain Sensitivity in Adults With Chronic Low Back Pain
Randomized control trial to examine the immediate effect of isometric exercise on pressure pain threshold (PPT) in adults with chronic low back pain.
- Trial name
- NCT06963658
- Testing
- Multiple repetition isometric wall squat, Multiple Isometric wall squat exercise + Double Leg Lower with Isometric Hold, Control quiet seated rest
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Taif University
Chronic Low-back Pain (cLBP)
The Effect Of Kinesiotape Application In Chronic Low Back Pain
This study was conducted to determine the effects of kinesiotaping (KT) and sham KT applied with exercise program on clinical parameters such as pain, sleep, and quality of life in postmenopausal women with chronic low back pain.
- Trial name
- NCT06684145
- Testing
- Kinesiotape application, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Firat University
Lower Back Pain Chronic
Randomized Trial for cLBP (Gokhale Project)
The study aims to compare the effectiveness of the Gokhale Method posture therapy for low back pain (LBP) management to standard physical therapy (PT) with posture training.
- Trial name
- Gokhale (NCT05657964)
- Testing
- Gokhale sensor
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Chronic Low-back Pain (cLBP)
Melatonin for Patients With Chronic Low Back Pain
Low back pain is one of the conditions causing more disability worldwide. The use of pain medications is substantial in patients with chronic LBP. But the efficacy of commonly used analgesics is modest.
- Trial name
- MELBACK (NCT06859957)
- Testing
- Melatonin 10 mg
- Where
- Netherlands
- Volunteers
- 222 people
- Sponsor
- Bart Koes
Chronic Low Back Pain (CLBP)
Chronic Low Back Pain: TOTALSPINE - UO04
Background: Low back pain (LBP) is the primary factor contributing to years lived with disability. In view of the close correlation between the functions of the body, which cannot be examined piecemeal but as an integrated…
- Trial name
- TOTALSPINE (NCT06895317)
- Testing
- Remote rehabilitation, Rehabilitation face to face
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Chronic Low Back Pain (CLBP)
Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain
This clinical trial aims to assess the effectiveness of different clinical techniques in treating patients with chronic low back pain (CLBP).
- Trial name
- CLBP (NCT06453291)
- Testing
- NSAIDs (Nonsteroidal Anti-Inflammatory Drugs):, Standard Physical Therapy, Neuromodulation via Dorsal Root Ganglion (DRG):
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iffat Anwar Medical Complex
Chronic Low-back Pain (cLBP)
Effects of a Land and Aquatic Exercise-based Program on Pain, Mobility and Quality of Life in Patients With Chronic Low Back Pain
The goal of this randomized clinical trial] is to study the effect of a combined aquatic and land-based exercise program compared to an aquatic program on pain, functional disability, and quality of life in adults with chronic…
- Trial name
- NCT06641570
- Testing
- Aquatic Exercise Program, Land-based Exercise Program
- Where
- Portugal
- Volunteers
- 41 people
- Sponsor
- Instituto Politécnico de Leiria
Chronic Low-back Pain
The Feasibility, Potential Efficacy, and Experiences of Using a Group-based Acceptance and Commitment Therapy Among Older People With Chronic Low Back Pain
No study has investigated the effects of ACT on community-dwelling Chinese older adults. Given that clinical practice guidelines have recommended exercise therapy for treating people with CLBP, a combination of ACT and exercise…
- Trial name
- NCT05919446
- Testing
- Acceptance and commitment therapy (ACT), back exercise
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Low Back Pain (CLBP)
Brain Network Stimulation for Chronic Low Back Pain.
This study looks at the non-invasive brain stimulation technique in people with chronic low back pain to see: How effective non-invasive brain stimulation is at improving pain intensity in people with chronic low back pain? How…
- Trial name
- NCT06902233
- Testing
- High-definition transcranial infraslow grey noise stimulation
- Where
- New Zealand
- Volunteers
- 164 people
- Sponsor
- University of Otago
Chronic Low-back Pain
TENS Reduces Movement-Evoked Pain in People With CLBP
In this cross-over study 25 patients with chronic low back pain (CLBP) were tested for pain relief in 2 conditions: while using the Transcutaneous Electrical Nerve Stimulation (TENS) application and without using it.
- Trial name
- NCT04090814
- Testing
- HeatTens (HV-F311-E)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Vrije Universiteit Brussel
Low Back Pain
Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects
The purpose of this study is to determine if buprenorphine hydrochloride (HCl) buccal film is effective in treating opioid-naive subjects, with moderate to severe chronic low back pain (CLBP), who require continuous…
- Trial name
- NCT01633944
- Testing
- Buprenorphine
- Where
- 60 sites in United States
- Volunteers
- 752 people
- Sponsor
- BioDelivery Sciences International
Chronic Low Back Pain (CLBP)
Validity and Reliability of Face-to-Face and Tele-Assessment of Core Stability and Functional Capacity
This study aims to compare the validity and reliability of core stability and functional capacity measurements when performed face-to-face and through tele-assessment in individuals with chronic low back pain.
- Trial name
- NCT07256873
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istinye University
Chronic Low Back Pain (CLBP)
Comparison Between Lumbar Stabilization Exercises and Lumbar Manipulation on Multifidus Muscle in Chronic Low Back Pain This Study Will Investigate and Compare the Effect of Lumbar Stabilization Exercises and Manipulation on Multifidus Muscle in Chronic Low Back Pain
Histological and morphological changes of multifidus muscle have been reported in lumbar disc herniation (LDH), but there is scarce research comparing the efficacy of different treatment programs that can correct multifidus…
- Trial name
- NCT06796023
- Testing
- Stretching and strengthening exercises for back muscles, Lumbar stabilization Exercises, Lumbar Manipulation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Chronic Lower Back Pain (CLBP), SIJ Arthropathy
Endoscopic Electrothermic Procedure of the Sacroiliac Joint
1. Determine the rate and incidence of peri-operative \& post-operative adverse events (complications, infections, re-operations, re-admissions) in the endoscopic approach for the treatment of SIJ arthropathy and chronic lower…
- Trial name
- ESIJ (NCT03920345)
- Testing
- MultiZYTE
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- joimax, Inc.
Chronic Low Back Pain (CLBP)
Proprioceptive, Calisthenic, and Kinesthetic Exercises for Chronic Low Back Pain
Numerous studies have emphasized the debilitating effects of chronic low back pain (CLBP), which persists for over 12 weeks and impacts approximately 20% of the global population.
- Trial name
- NCT06751719
- Testing
- core stabilization exercises, heat therapy, proprioceptive exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Chronic Low-back Pain (cLBP)
Exercise-Based Strategies for Chronic Back Pain
This randomized, controlled, five-arm, parallel-group trial will evaluate the effects of 8 weeks of supervised resistance training and developmental position-based exercise, with or without real-time non-invasive intra-abdominal…
- Trial name
- BACK-FIT (NCT07475481)
- Testing
- Gym settings, Physio settings, Home - based settings: exercises based on developmental positions
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Charles University, Czech Republic
Chronic Low Back Pain (CLBP), Distraction Methods
The Effect of Attention Distraction on the Adherence to Exercise, in Chronic Low Back Pain Patients.
This randomized controlled trial aims to investigate whether the use of an attention distraction application during exercise increases patient adherence to exercise programs in chronic non-specific low back pain (CNSLBP).
- Conditions
- Chronic Low Back Pain (CLBP), Distraction Methods, Adherence to Care
- Trial name
- PAINLESS (NCT07192809)
- Testing
- Stabilisation exercise, resistance exercise and distraction task, stabilisation exercise and resistance exercises
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly