Clinical trials: Chronic Lower Back Pain
Chronic Low Back Pain (CLBP)
Impairment Based Treatment Versus Modified Functional Restoration Program in Chronic Low Back Pain Patients
The aim of this feasibility study is to evaluate the practicality of conducting a future randomized controlled trial comparing two rehabilitation approaches for older adults with degenerative chronic low back pain…
- Trial name
- FIRM-CLBP (NCT07699419)
- Testing
- Impairment-based trearment, Modified Functional restoration program
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Back Pain
Celebrex vs Tramadol in the Treatment of Chronic Lower Back Pain.
This study investigates if Celebrex is as effective as tramadol hydrochloride (Ultram) for patients with chronic low back pain, when administered over a 6-week period.
- Trial name
- NCT00290901
- Testing
- Tramadol Hydrochloride 50mg, Celebrex 200mg
- Where
- 54 sites in United States, Puerto Rico
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Low Back Pain
Reliabılıty,Validity Of The Turkish Version Of The NIH-Minimal Dataset
This study, we performed the Turkish version validity and reliability of the NIH Task Force's Recommended Multidimensional Minimal Dataset
- Trial name
- NCT06049719
- Testing
- NIH Task Force's Recommended Multidimensional Minimal Dataset
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Gazi University
Low Back Pain, Chronic Low-back Pain
Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain
This Study is for our continued study of the Thoracolumbar Fascia (TFL) in patients with and without low back pain by our experienced multidisciplinary team: Vincent Wang PhD, VT Biomedical Engineering \& Mechanics (BEAM).
- Conditions
- Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
- Trial name
- NCT06818175
- Testing
- Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Low Back Pain
Application of LED Photobiomodulation in the Treatment of Chronic Low Back Pain
Lumbar pain, or low back pain, may be defined as pain or discomfort located from the lower portion of the costal margin to the gluteal folds, with or without referred pain in the legs.
- Trial name
- NCT04003545
- Testing
- LED Photobiomodulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Chronic Low Back Pain
Efficacy of a Classification Based 'Cognitive Functional Therapy' in Nurses With Non Specific Chronic Low Back Pain
A series of case-studies to explore the efficacy of classification based cognitive functional physiotherapy according to the classification system proposed by Peter O'Sullivan in specific nursing population with non specific…
- Trial name
- NCT01882686
- Testing
- Classification Based Cognitive Functional Therapy
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Back Pain, Low, Back Pain
Quality Improvement re: Choosing Wisely Back Pain Measures
As
- Conditions
- Back Pain, Low, Back Pain, Back Pain Lower Back Chronic
- Trial name
- SCV LBP (NCT05413070)
- Testing
- Multimodal approach to QI for Low-Value Care
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Low Back Pain, Chronic Low Back Pain
Evaluation of Dynamic Stability in the Low Back Pain Patient
The main objective of this study is to compare on day 0 the maximum Lyapunov exponent (lmax, an indicator of local dynamic stability) of chronic low back pain patients versus that of healthy volunteers matched for age (± 5…
- Trial name
- SDL (NCT02059317)
- Testing
- Flexion-extension in the sagittal plane, Rotation in a transverse plane, Complex movement in three dimensions
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Low Back Pain
Measurement of Substance P in Saliva of Low Back Pain Patients
The purpose of this study is to compare the levels of Substance P in saliva, in patients with severe chronic low back pain and in subjects without it.
- Trial name
- NCT00735735
- Testing
- The taking of a saliva sample from each subject.
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kovacs Foundation
Chronic Low Back Pain
A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
To administer the MSDR® (Musculoskeletal Disorder Reporting) instrument to document the musculoskeletal profile of patients with chronic low back pain, a prospective, non-randomized, multicenter treatment trial
- Trial name
- NCT00732394
- Testing
- MSDR
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedAppraise, Inc.
Low Back Pain
The Effectiveness of Telerehabilitation Modalities in Physical Therapy in the Management of Chronic Low Back Pain
Low back pain (LBP), a common disorder, causes disability, functional decline and high health care costs. Patient care programs include specific exercises for promoting function and improving health.
- Trial name
- NCT03756740
- Testing
- telerehabilitation and physical therapy, control
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Spinal Stenosis Lumbar, Surgical Site Infection
Efficacy of ActiveMatrix on Spinal SSI Rate
This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.
- Conditions
- Spinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back Chronic
- Trial name
- NCT05297513
- Testing
- ActiveMatrix
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS)
Two Point Discrimination
SPECIFIC AIMS Pain in both youth and adults is a complex, subjective and personal experience, and remains poorly understood. One particularly perplexing dimension of some forms of pain is the tendency of pain to spread outside of…
- Conditions
- Ehlers-Danlos Syndrome (EDS), Complex Regional Pain Syndrome (CRPS), Amplified Musculoskeletal Pain Syndrome (AMPS), Low Back Pain
- Trial name
- TPD (NCT03686748)
- Testing
- Two-point discrimination training, One-point discrimination training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Low-back Pain
Muscle Energy Technique and Foam Roller Self Myofascial Release in Two-wheeler Riders With Chronic Low Back Pain
Pain in the lower back is a major concern in today's era due to prolonged sitting in two-wheeler riders, mainly due to hamstring tightness. It also creates physical disability and impairment in activities of daily living.
- Trial name
- NCT06017804
- Testing
- Muscle energy technique, Self-myofascial release technique
- Where
- Saudi Arabia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- King Saud University
Low Back Pain
Pain Sensory Profile Changes Following Treatment of Chronic Low Back Pain
Several cross-sectional studies have demonstrated that patients with chronic low back pain have higher levels of pain sensitivity (local and widespread) when compared to controls.
- Trial name
- LBP (NCT03748849)
- Testing
- Physiotherapy
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Back Pain Lower Back Chronic
Behavioral and Emotional Factors Associated With Pain Severity
The planned research will address the behavioral and emotional factors associated with low back pain rather than a structural and biological cause.
- Trial name
- NCT05232747
- Testing
- Diagnostic Test
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Chronic Low-back Pain
The Effect of an Acute Bout of Exercise on Pain Sensitivity and Clinical Pain in Adults With Chronic Low Back Pain
The goal of this interventional study is to investigate the efficacy of an acute bout of exercises on pain sensitivity (primary aim) and clinical pain intensity (secondary aim) among adults with Chronic Low Back Pain.
- Trial name
- NCT05779748
- Testing
- Single bout of exercise
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taif University
Chronic Pain
Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study
The purpose of this study is to investigate whether a psycho-therapeutic approach, group Cognitive Behavioral Therapy (CBT) plus a relapse prevention program, Therapeutic Interactive Voice Response (TIVR), modifies the…
- Trial name
- NCT01794988
- Testing
- Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Back Pain Lower Back Chronic
Yoga vs. Physical Therapy vs. Education for Chronic Low Back Pain in Minority Populations
A randomized controlled trial for chronic low back pain in predominantly minority populations with three treatment arms: yoga, physical therapy, and education.
- Trial name
- Back to Health (NCT01343927)
- Testing
- Weekly yoga classes, Individual physical therapy treatment, Education
- Where
- 8 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center