Clinical trials: Chronic Nerve Pain
Pelvic Pain Syndrome, Sacroiliac Disorder
Chronic Pelvic Pain in Females and Males
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly.
- Conditions
- Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder
- Trial name
- NCT06102733
- Testing
- Rehabilitation therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain
High Frequency RF Current Effects on Muscle Pain and Function
The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called "TECAR") on pain and functional movement in individuals with a musculoskeletal injury or pain.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain, Hamstring Injury, Muscle; Injury, Quadriceps (Thigh)
- Trial name
- NCT05345015
- Testing
- Radiofrequency Energy Transfer, Transcutaneous Nerve Stimulation
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Low Back Pain
Percutaneous Neuromuscular Electrical Stimulation in Patients With Chronic Low Back Pain
Chronic low back pain is a common musculoskeletal condition affects the general population. Low back pain constitutes a major burden to health care system and society.
- Trial name
- PNMESlowback (NCT04243915)
- Testing
- Percutaneous neuromuscular electrical stimulation (PNMES) plus motor control exercise program, TENS plus motor control exercise program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad Rey Juan Carlos
Limbs Arthrosis, Non Arthrosic Limbs Arthralgia
Association of Transcutaneous Electrical Nerve Stimulation and Hypnosis
At Saint-Antoine's hospital, in CETD a multidisciplinary team takes care of patients with chronic pain. Free-drug techniques are available to reduce their consumption of analgesics.
- Conditions
- Limbs Arthrosis, Non Arthrosic Limbs Arthralgia, Chronic Lomboradiculalgia, Chronic Back Pain
- Trial name
- HYPTENS (NCT01944150)
- Testing
- Transcutaneous electrical nerve stimulation, Transcutaneous electrical nerve stimulation and hypnosis
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lower Back Pain
Peripheral Nerve Stimulation With the SPRINT® System in Chronic PSIJC Pain
Chronic lower back pain is a significant cause of disability, affecting 21-68% of people 60 years of age and older (source). Of these cases, 15-30% are attributed to posterior sacroiliac joint complex (PSIJC) pain (source)…
- Trial name
- NCT07166952
- Testing
- SPRINT PNS System
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Medical University of South Carolina
Pain Management
TENS for Testicular Pain (ICO): A Randomized Controlled Trial
Idiopathic Chronic Orchialgia (i.e., testicular pain) is a challenging condition to treat, with unresolved testicular pain leading to distress, diminished activities of daily living and decreased quality of life.
- Trial name
- NCT04866784
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Jennifer E. Lee
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus
Acute Pain, Chronic Post Operative Pain
Understanding the Acute Pain Phenotype in Patients Undergoing Surgery
The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenotypes such as different levels of concern about pain, sleep issues, and…
- Conditions
- Acute Pain, Chronic Post Operative Pain, Opioid Use
- Trial name
- NCT06466941
- Testing
- regional anesthesia, no regional anesthesia, acute pain consultation
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Proctalgia
Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia
The main objective is to evaluate the analgesic efficacy of botulinum toxin type A in refractory chronic proctalgia one month after a bilateral injection of 50 units of Botox ® in the ganglion Impar (total dose = 100 units)
- Trial name
- Impartox (NCT01331356)
- Testing
- Botox
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- Nantes University Hospital
Chronic Low-back Pain
TENS Reduces Movement-Evoked Pain in People With CLBP
In this cross-over study 25 patients with chronic low back pain (CLBP) were tested for pain relief in 2 conditions: while using the Transcutaneous Electrical Nerve Stimulation (TENS) application and without using it.
- Trial name
- NCT04090814
- Testing
- HeatTens (HV-F311-E)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Vrije Universiteit Brussel
TMJ Pain
Nerve Block Treatment for Chronic Jaw Pain
Study Summary: Nerve Block Treatment for Chronic Jaw Pain This study is being conducted at the TMJ (temporomandibular joint) clinic, which is part of the oral and maxillofacial surgery department.
- Trial name
- NCT06966557
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Bnai Zion Medical Center
Low Back Pain
Auricular Vagus Nerve Stimulation for Chronic Pain
This proposal aims to investigate the treatment effect and underlying mechanism of transcutaneous acupuncture stimulation on chronic low back pain.
- Trial name
- NCT03959111
- Testing
- Stimulation at Location 1, Stimulation at Location 2
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Massachusetts General Hospital
Neuropathic Pain
The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin
Pain as a result of nerve injury (neuropathic pain) is a particularly severe form of chronic pain. Common examples of neuropathic pain are pain due to diabetes and shingles.
- Trial name
- NCT01669967
- Testing
- Lidocaine, Diphenhydramine
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Tennis Elbow
Comparative Study Between Different Mobilization Techniques for Patients With Chronic Tennis Elbow
Background: Tennis elbow is a common musculoskeletal disorder affecting the functional activities of daily living through common extensor tendinopathy.
- Trial name
- RCT (NCT06812377)
- Testing
- Maitland joint mbilization, mulligan mobilization, radial nerve mobilization
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Fibromyalgia
The Effect of Transcutaneous Posterior Tibial Nerve Stimulation in Patients With Fibromyalgia
This study aimed to investigate the effectiveness of posterior tibial nerve stimulation (PTNS) in reducing pain, improving quality of life, and decreasing disease severity in patients with fibromyalgia.
- Trial name
- NCT05937711
- Testing
- Transcutaneous Posterior Tibial Nerve Stimulation + Duloxetine 30 MG, Duloxetine 30 MG
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ilker Fatih Sari
Chronic Neck Pain
Phrenic Nerve Infiltration in Neck Pain
Neck pain frequently present comorbidities in peridiaphragmatic organs. The innervation of these organs include the phrenic nerve. It is known that peridiaphragmatic organs trigger referred pain in the neck area.
- Trial name
- PAINOMICS (NCT05605639)
- Testing
- Bupivacaine
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Chronic Pain
Effectiveness and Safety of Implantable Neurostimulation Systems for Chronic Pain: A Spanish Multicenter Study (STIM-RENASED)
Chronic pain is a prevalent condition that negatively affects patients' quality of life. Implantable neurostimulation therapies have been proposed as a treatment option for chronic pain.
- Trial name
- STIM-RENASED (NCT05770700)
- Where
- 16 sites in Spain
- Volunteers
- 504 people
- Sponsor
- Sociedad Espanola del Dolor
Chronic Pain, Neuroma
Comparative Evaluation of Intraneuroma and Perineuroma Botulinum Toxin Type A Injection Techniques for Chronic Neuroma Pain After Combat-Related Amputation
Patients with combat-related amputations frequently experience chronic neuroma pain that may interfere with rehabilitation, prosthesis use, mobility, sleep, and quality of life.
- Conditions
- Chronic Pain, Neuroma, Botulinium Toxin-A, Combat Trauma
- Trial name
- IN-PERI NEUROM (NCT07624877)
- Testing
- Botulinum toxin type A injection
- Where
- 2 sites in Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Postoperative Pain, Cerebral Palsy
Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy
Popliteal block is a technique for providing postoperative pain management in children. In this randomized double-blinded study, the investigators evaluated the effects of preoperative popliteal nerve block on postoperative pain…
- Trial name
- NCT02507700
- Testing
- Popliteal block, Sevoflurane, Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Amputation
Target Muscle Re-innervation and Regenerative Peripheral Nerve Interfaces Alone and in Combination for the Treatment of Residual and Phantom Limb Pain in Cancer Patients Who Have Received an Amputation
This clinical trial evaluates two surgical techniques (targeted muscle re-innervation [TMR] and regenerative peripheral nerve interfaces [RPNI]) alone and in combination for the alleviation of chronic residual limb and phantom…
- Trial name
- NCT06840262
- Testing
- Questionnaire Administration, Regenerative Peripheral Nerve Interface Surgery, Targeted Muscle Reinnervation
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- M.D. Anderson Cancer Center