Clinical trials: Chronic Non-Cancer Pain
Chronic Pain, Insomnia
The Efficacy of CALPXT96™in Improving Sleep Quality in Patients With Chronic Non-cancer Pain
California Poppy has been traditionally used in Herbal Medicine as an analgesic, mild sedative and/or sleep aid. However there are no human clinical trial data to support its use.
- Trial name
- CALPXT96 (NCT02232256)
- Testing
- CALPXT96
- Where
- Canada
- Sponsor
- 9305-9954 Quebec Inc
Chronic Non-cancer Pain
Cannabis Oil for Chronic Non-Cancer Pain Treatment
Cannabis is being prescribed medically for chronic non-cancer pain despite limited evidence whether or not it works to reduce average pain in patients with chronic non-cancer pain.
- Trial name
- CONCEPT (NCT03635593)
- Testing
- CBD, CBD+THC
- Where
- 2 sites in Canada
- Volunteers
- 309 people
- Sponsor
- Hamilton Health Sciences Corporation
Opioid Withdrawal (Disorder)
Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal
Stopping prescription opioid pain medications can be difficult due to withdrawal symptoms. This study will test if LUCEMYRA helps reduce withdrawal symptoms and helps more people reduce their opioid dose compared to placebo.
- Trial name
- TAPER (NCT04070157)
- Testing
- Lofexidine
- Where
- 12 sites in United States
- Volunteers
- 4 people
- Sponsor
- USWM, LLC (dba US WorldMeds)
Chronic Myeloproliferative Disorders, Leukemia
Music in Reducing Anxiety and Pain in Adult Patients Undergoing Bone Marrow Biopsy for Hematologic Cancers or Other Diseases
RATIONALE: Listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain. PURPOSE: This randomized clinical trial is studying how well music works in reducing anxiety and pain in adult…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Lymphoproliferative Disorder
- Trial name
- NCT00376922
- Testing
- music therapy
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Advanced Cancer
Long Term Safety of Sativex Oromucosal Spray (Sativex®; Nabiximols) as Adjunctive Therapy in Patients With Uncontrolled Persistent Chronic Cancer Related Pain
This was a six-month open-label extension (OLE) study to evaluate the safety of long-term nabiximols (Sativex®) therapy when used as an adjunctive treatment in participants with advanced cancer.
- Trial name
- NCT01337089
- Testing
- Nabiximols
- Where
- 128 sites in United States, Australia and 16 more
- Volunteers
- 660 people
- Sponsor
- Jazz Pharmaceuticals
Peripheral Neuropathy
Intrathecal Bolus Doses of Ziconotide
The purpose of this study is to evaluate if the effect of ziconotide can be tested by intrathecal bolus doses.
- Trial name
- ZicBol (NCT01373983)
- Testing
- Ziconotide
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- University Hospital, Linkoeping
Chronic Pain
Medication Review Improves Pain Management and Quality of Life in Chronic Pain
The goal of this parallel-group, single-blinded, randomized study is to conduct Medication Review (MR) Type III in chronic non-cancer pain patients to optimize drug therapy and measure it's influence on Pain Intensity and Quality…
- Trial name
- NCT06997861
- Testing
- Medication Review Type III, Usual Care
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Polytechnic Institute of Porto
Constipation
Efficacy and Safety of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain
This study will evaluate the efficacy and safety of tegaserod in opioid-induced constipation in patients with non-cancer pain.
- Trial name
- NCT00365820
- Testing
- Tegaserod
- Where
- 59 sites in United States
- Volunteers
- 670 people
- Sponsor
- Novartis
Chronic Pain, Opioid-use Disorder
Validation of the ASI-SR Form in a Population of Chronic Non-cancer Pain Patients
The Swedish version of ASI-SR has shown good feasibility in assessment of addiction patients functioning compare to long and time-consuming ASI, which is upp to date golden standard in Sweden.
- Conditions
- Chronic Pain, Opioid-use Disorder, Quality of Life, Risk Reduction
- Trial name
- ASI-SR (NCT04998734)
- Testing
- ASI-SR
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Uppsala University
Anxiety Disorder, Cancer Survivor
Quality of Life in Younger Leukemia and Lymphoma Survivors
RATIONALE: Collecting information about the effect of hematologic cancer and its treatment on quality of life may help doctors learn more about the disease and plan the best treatment.
- Conditions
- Anxiety Disorder, Cancer Survivor, Fatigue, Leukemia
- Trial name
- NCT00956475
- Testing
- telephone-based intervention, questionnaire administration, assessment of therapy complications
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Case Comprehensive Cancer Center
Cancer
Acupuncture in Treating Mucositis-Related Pain Caused by Chemotherapy in Patients Undergoing Stem Cell Transplantation
RATIONALE: Acupuncture may be effective in relieving mucositis-related pain caused by chemotherapy in patients undergoing stem cell transplantation.
- Trial name
- NCT00060021
- Testing
- acupuncture therapy, management of therapy complications, pain therapy
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Chronic Non Cancer Pain
Pharmacist for Detecting Opioid Misuse
Opioid use is increasing in Western countries and is associated with harms as hospitalization, addiction and deaths(1). Community pharmacists interact frequently with patients, giving them the opportunity to identify and prevent…
- Trial name
- NCT04544696
- Where
- France
- Volunteers
- 414 people
- Sponsor
- University Hospital, Montpellier
Chronic Non-Cancer Pain
Preventive Interventions for Chronic Pain Worsening
This is an open label randomized controlled trial (RCT), which will be conducted with patients of the Copenhagen Wound Healing Center at Bispebjerg Hospital in Copenhagen (DK).
- Trial name
- NCT06351046
- Testing
- Virtual Reality-based Pain Self-management program
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Opioid-induced Constipation
Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
This study will evaluate the safety and efficacy of Tegaserod in opioid-induced constipation (OIC) in patients with non-cancer pain.
- Trial name
- NCT00399659
- Testing
- Tegaserod
- Where
- 57 sites in United States
- Volunteers
- 360 people
- Sponsor
- Novartis
Asymptomatic Bacteriuria in Subjects Not Requiring Assisted Bladder Emptying, Asymptomatic Bacteriuria in Subjects Relying on Some Type of Catheter
Effects of Microbiological and Immunological Factors on the Lower Urinary Tract
Millions of patients of all ages suffer worldwide from diverse urinary pathologies, such as lower urinary tract (LUT) dysfunction, bladder pain syndrome, urinary tract infections (UTIs), or bladder cancer.
- Conditions
- Asymptomatic Bacteriuria in Subjects Not Requiring Assisted Bladder Emptying, Asymptomatic Bacteriuria in Subjects Relying on Some Type of Catheter, Recurrent Non-catheter Associated UTIs, Acute Catheter-associated UTI (CAUTI)
- Trial name
- MiLUT (NCT07494864)
- Where
- Switzerland
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Pain, Major Depressive Disorder
The Internet Therapy for Depression Trial
The objective of this trial is to collect data on the feasibility, acceptability, and preliminary effectiveness of internet delivered Cognitive Beaviour Therapy (iCBT) and Acceptance and Commitment Therapy (iACT) interventions…
- Trial name
- INTEREST (NCT04009135)
- Testing
- internet delivered cognitive behavioural therapy (iCBT), online delivered acceptance and commitment therapy (iACT), Attention Control (AC)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Memorial University of Newfoundland
Malignant Neoplasms of Independent (Primary) Multiple Sites
Chronic Non-Malignant Pain in Cancer Patients at a Supportive Care Clinic
The goal of this research study is to learn how frequently cancer patients in the Supportive Care Center have chronic, non-malignant pain.
- Trial name
- NCT03043378
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- M.D. Anderson Cancer Center
Opioid Use, Opioids; Harmful Use
Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy
Chronic pain management is complex, with healthcare providers historically relying on prescribing opioid medications such as morphine.
- Conditions
- Opioid Use, Opioids; Harmful Use, Hyperalgesia, Pain, Chronic
- Trial name
- NCT04902547
- Testing
- Patient Education Workshop (PEWs), Multidisciplinary Tapering Program
- Where
- 4 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Non-cancer Pain
Exploring Long-term Pain Relief with 5% Dextrose Added to Local Anesthetic
The goal of this single-arm, non-randomized, open-label trial is to determine whether adding a 5% dextrose solution to a local anesthetic can improve outcomes in patients with chronic non-cancer pain.
- Trial name
- NCT06617065
- Testing
- Addition of 1 mL of 50% dextrose solution to the usual local anesthetic solution of choice for each patient.
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- The Seekers Centre