Clinical trials: Chronic Obstruct Airways Disease
Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Exacerbation
Wearable Devices in the Recovery Phase of Acute Exacerbations of COPD (AECOPDs)
The purpose the study is to successfully characterize the recovery phase of acute exacerbations of COPD in the outpatient setting using remotely captured physiologic data from wearable devices, to compare this with patient…
- Trial name
- NCT05776654
- Testing
- Biometric wearable devices
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Obstructive Pulmonary Disease, Aging
Fiber Metabolism in Chronic Obstructive Pulmonary Disease
The impact of fiber intake on short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare changes in SCFA metabolism after inulin vs.
- Trial name
- NCT04459156
- Testing
- Fiber Inulin
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
COPD
Effect of Brovana and Tiotropium in Chronic Obstructive Pulmonary Disease (COPD)
This will be a double-blind crossover trial in 20 patient with stable COPD. Data from this study will provide proof-of-concept information on whether the (anticipated) additional bronchodilator effect of Brovana added to…
- Trial name
- NCT00773786
- Testing
- Arformoterol (Brovana)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Trinity Health Of New England
Pulmonary Disease, Chronic Obstructive
Benefits of Lightweight Ambulatory Oxygen Systems for Individuals With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) affects over 14 million people in the United States. It is the fourth leading cause of death and the only leading cause of death for which mortality rates are rising.
- Trial name
- NCT00325754
- Testing
- E-Cylinder, Lightweight Cylinder
- Where
- 10 sites in United States
- Volunteers
- 22 people
- Sponsor
- University of Minnesota
Tabagism, Lung Cancer
Use of a Smartphone Application on the Detection of Complications Related to Smoking
Smokers do not know the symptoms of cancer and wait on average 5 months with symptoms before consulting. 80% of lung cancers are diagnosed at too late and incurable stage.
- Conditions
- Tabagism, Lung Cancer, Chronic Obstructive Pulmonary Disease
- Trial name
- APPLITABAC (NCT04048954)
- Testing
- Applitabac
- Where
- France
- Volunteers
- 5,671 people, healthy volunteers welcome
- Sponsor
- Weprom
Asthma, COPD
Chronic Obstructive Pulmonary Disease and Asthma in Workers at Navanakorn Industrial Zone, Thailand
The goal of this observational study is to determine the prevalence of asthma and chronic obstructive pulmonary disease (COPD) among workers in an industrial zone in Thailand.
- Trial name
- NCT07383896
- Testing
- Pulmonary function test
- Where
- Thailand
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Chronic Obstructive Pulmonary Disease, Emphysema or COPD
The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility
In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the…
- Trial name
- NCT06163131
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Aarhus University Hospital
Chronic Obstructive Pulmonary Disease, Emphysema
Cost-Effectiveness of Lung Volume Reduction Surgery
Lung volume reduction surgery (LVRS) has been advanced as a therapy to significantly improve quality of life in patients with COPD, but to date no controlled studies have evaluated the impact of LVRS.
- Trial name
- NCT00013156
- Testing
- Effectiveness of Lung Reduction Therapy
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
Myotrace: An Evaluation of a Novel Critical Illness Monitoring System
There are 24,000 admissions each year to Intensive Care Units (ICU) in the United Kingdom due to pneumonia, asthma and a common condition called chronic obstructive pulmonary disease (COPD), with rates of death of 10%, 40% and…
- Trial name
- NCT01361451
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
COPD, Pulmonary Hypertension
Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease
This study plans to learn about heart function among individuals with chronic obstructive pulmonary disease (COPD). In particular, the investigators want to understand the different patterns of right ventricular response during…
- Conditions
- COPD, Pulmonary Hypertension, Right Ventricular Dysfunction, Exercise
- Trial name
- NCT05896579
- Testing
- Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Chronic Obstructive Pulmonary Disease
INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol
This protocol describes a randomised controlled trial to test the hypothesis that 6 months of treatment with tiotropium and olodaterol will result in a reduction in bacterial load, an improvement in neutrophilic inflammation and…
- Trial name
- INCOGNITO (NCT03152149)
- Testing
- Tiotropium & olodaterol, fluticasone furoate & vilanterol
- Where
- 4 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Dundee
COPD Exacerbations, Death
Hospitalary Chronic Obstructive Pulmonary Disease Registry
The purpose of this study is to create an institutional registry of Chronic Obstructive Pulmonary disease through a prospective survey based on epidemiological data, risk factors, diagnosis, prognosis, treatment, monitoring and…
- Trial name
- NCT02659189
- Where
- Argentina
- Volunteers
- 300 people
- Sponsor
- Hospital Italiano de Buenos Aires
Pulmonary Disease, Chronic Obstructive, Lung Diseases
A Study To Examine The Safety, Pharmacokinetics And Pharmacodynamics Of PF-03635659 In Patients With Chronic Obstructive Pulmonary Disease
PF-03635659 is being developed for the treatment of chronic obstructive pulmonary disease. This is a study to examine the safety, pharmacokinetics and pharmacodynamics of PF-03635659 in patients with Chronic Obstructive Pulmonary…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Respiratory Tract Diseases, Chronic Obstructive Airway Disease
- Trial name
- NCT01033487
- Testing
- active comparator, Low Dose PF-03635659, Mid Dose PF-03635659
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Pfizer
Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation
Comparison of the Cardiopulmonary and Gaz-exchange Response Between the Six-minute Stepper Test and the Incremental Cardiopulmonary Exercise Testing in Patients With Chronicle Obstructive Pulmonary Disease
Chronicle obstructive pulmonary disease is a worldwide cause of mortality and morbidity. This systemic disease progressively leads to dyspnea, muscle wasting and exercise capacity impairment.
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Rehabilitation, 6-minute Stepper Test
- Trial name
- PH-6MST (NCT04008615)
- Testing
- 2 times : 6-minute stepper test with cardiorespiratory parameters and gaz exchange monitoring (with a rest of 20min between each test).
- Where
- 3 sites in France
- Volunteers
- 65 people
- Sponsor
- ADIR Association
Pulmonary Disease, Chronic Obstructive
High Dose Trial in COPD
The primary objective of this study was to compare the efficacy and safety of 200 μg and 400 μg of BEA 2180 BR to tiotropium 5 μg and placebo when each was delivered by the Respimat® Inhaler once daily for four weeks in patients…
- Trial name
- NCT00128440
- Testing
- BEA 2180 BR, tiotropium
- Where
- 13 sites in United States
- Volunteers
- 78 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Effects of Pranayama Breathing Technique in Patients With Chronic Obstructive Pulmonary Disease
It will be randomized controlled trial. The research will be conducted at Bahawal Victoria hospital Bahawalpur and civil hospital Bahawalpur. We take 60 patients (Epitool), Patients will be allocated randomly in two groups.
- Trial name
- NCT05651958
- Testing
- Nebulizer, Breathing Technique
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Improving Cardiovascular Health in Patients With Chronic Obstructive Pulmonary Disease
Researchers have found a link between chronic obstructive pulmonary disease (COPD) and heart disease; however, a link is all they have found.
- Trial name
- NCT03819517
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pulmonary Disease, Chronic Obstructive
Tiotropium (Spiriva) Rehabilitation Study
The study was designed to determine whether tiotropium inhalation capsules, compared to placebo, enhances the improvement in exercise tolerance seen in patients with chronic obstructive pulmonary disease (COPD) who participate in…
- Trial name
- NCT00274521
- Testing
- Tiotropium
- Where
- 19 sites in United States
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
The Effect of Respiratory Muscle Strength and Functional Capacity on Posture and Balance
As a result of the study, inspiratory muscle strength, posture and physical performance evaluations of individuals with Chronic Obstructive Pulmonary Disease will be made, suggestions will be made to help individual postural…
- Trial name
- NCT05005533
- Testing
- Observational
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Abant Izzet Baysal University
Alpha-1-Antitrypsin Deficiency, Chronic Obstructive Lung Disease
Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency
The objective of this study is to evaluate the safety and effectiveness of the RePneu Lung Volume Reduction Coil (LVRC) in patients with Alpha-1-Antitrypsin deficiency (AATD) caused emphysema.
- Conditions
- Alpha-1-Antitrypsin Deficiency, Chronic Obstructive Lung Disease, Emphysema
- Trial name
- LuReCAA (NCT02273349)
- Testing
- Lung Volume Reduction Coil (PneumrX Inc.)
- Where
- 2 sites in Denmark, Germany
- Sponsor
- University Hospital, Saarland
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