Clinical trials: Chronic Obstructive Pulmonary
Chronic Obstructive Pulmonary Disease
Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation?
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease starting point characterized by multiple systemic effects as cognitive dysfunction.
- Trial name
- DysCo (NCT02493790)
- Testing
- Cognitive and motor performances
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- 5 Santé
COPD
COPD at a Street Level
The trial investigates and describes the prevalence of COPD among socially vulnerable individuals who come in contact with a mobile clinic and investigates the effect of opportunistic screening for COPD in these vulnerable…
- Trial name
- NCT05660460
- Testing
- Spirometry
- Where
- Denmark
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Diabetes Mellitus, Chronic Heart Failure
Randomized Controlled Trial of Home Telemonitoring for Elderly People
The DREAMING clinical trial is part of the DREAMING project, which has the objective to demonstrate that the DREAMING platform consisting of integrated health monitoring, alarm handling and videoconferencing services produces…
- Conditions
- Diabetes Mellitus, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease
- Trial name
- Dreaming (NCT00893685)
- Testing
- Wireless monitors for disease specific clinical parameters.
- Where
- 6 sites in Denmark, Estonia and 4 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Health Information Management, Belgium
Pulmonary Disease, Autonomic Dysfunction
Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants
This study will explore the a Qigong based exercise intervention, here referred to as Meditative Movement (MM), to ameliorate the symptoms associated with chronic obstructive pulmonary disease (COPD) and its co-morbidities.
- Conditions
- Pulmonary Disease, Autonomic Dysfunction, COPD
- Trial name
- MMforFA (NCT02612389)
- Testing
- Meditative Movement taught via DVD
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
COPD
Assessment of Severity and Prognosis in Elderly Patients With COPD and Complex Chronic Comorbidities
Cigarette smoking, the major risk factor for Chronic Obstructive Pulmonary Disease (COPD), causes systemic effects, such as systemic cellular and humoral inflammation, that could substantially contribute to the development of…
- Trial name
- NCT01893918
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
COPD, Asthma
Biomarker Assay Validation in Healthy Smokers and COPD Smokers and Ex-smokers
This study will collect sputum samples from healthy smokers, COPD smokers and COPD ex-smokers to analyse biomarkers of inflammation
- Trial name
- NCT02490358
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Giant Cell Arteritis (GCA), Polymyalgia Rheumatica (PMR)
AYLo - AutoimmunitY and Loss of y
The AYLo study (AutoimmunitY and Loss of y - Investigating the Role of Hematopoietic Mutations and Mosaic Mutation in the Y Chromosome in Autoimmune Rheumatologic Diseases) aims to systematically investigate hematopoietic…
- Conditions
- Giant Cell Arteritis (GCA), Polymyalgia Rheumatica (PMR), ANCA Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathies
- Trial name
- AYLo (NCT06696027)
- Testing
- Single nucleotide polymorphisms (SNP), 3'mRNA sequencing, Enzyme-linked immunosorbent assay (ELISA) and Legendplex Array
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Diabetes, Depression
Self-Efficacy Enhancing Interviewing Techniques Study
Patient self-efficacy, or confidence in one's ability to take the necessary steps to achieve a goal, has been shown to influence a number of important health behaviors and outcomes.
- Conditions
- Diabetes, Depression, Anxiety, Asthma
- Trial name
- SEE-IT (NCT00643435)
- Testing
- Self-efficacy enhancing interviewing techniques training, Control intervention
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obstructive Ventilatory Disorders
Study of Chronic Exposure of the Population Living on the Atlantic Coast and on the Caribbean Coast, in Martinique, During the Stranding Period and Outside the Stranding Period of Sargassum Seaweeds
Sargassum are pelagic brown sea algae. Two species grow on the surface of the ocean and drift freely with ocean currents in the form of slicks: the pelagic Sargassum fluitans and Sargassum natans.
- Trial name
- SÉSAR (NCT05564546)
- Testing
- FeNO (fractional exhaled nitric oxide), Spirometry, Physical examination
- Where
- France
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- University Hospital Center of Martinique
Chronic Obstructive Pulmonary Disease, Aging
Fiber Metabolism in Chronic Obstructive Pulmonary Disease
The impact of fiber intake on short chain fatty acid (SCFA) metabolism has not been studied in subjects suffering from COPD. The purpose of this study is to compare changes in SCFA metabolism after inulin vs.
- Trial name
- NCT04459156
- Testing
- Fiber Inulin
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
COPD
Urdu Translation, Validity and Reliability of Dyspnea 12 (D-12)
Dyspnea is a distressing symptom with pain like perception. The object of study is to translate a tool that measure overall dyspnea severity.
- Trial name
- NCT04879095
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Subjects
AZD8871 is a new chemical entity possessing long-acting effect in a single molecule which presents a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an…
- Trial name
- NCT02814656
- Testing
- AZD8871
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive
To Assess the Excretion Balance and Pharmacokinetics of a Single Oral Dose of [14C]SB-681323 in Healthy Adult Males
SB-681323 is a p38 MAP kinase inhibitor and is currently under development by GlaxoSmithKline. This will be an open label study conducted at one site.
- Trial name
- NCT00564746
- Testing
- A single 10 milligram (50 microcurie) oral dose of [14C]SB-681323
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD
Studies on resting human muscle show that ingestion of the branched-chain amino acids (BCAA): leucine, valine and isoleucine have an anabolic effect on muscle protein metabolism.
- Trial name
- NCT01418469
- Testing
- Caseinate, Whey protein isolate, Soy
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Chronic Obstructive Pulmonary Disease
Thora-3DI™ for Evaluation of Severity of Chronic Obstructive Pulmonary Disease (COPD)
To demonstrate differences in tidal breathing patterns measured by SLP(Structured Light Plethysmography) between healthy subjects and COPD (chronic obstructive pulmonary disease).
- Trial name
- SLPCOPD (NCT03492359)
- Testing
- Thora-3Di, Body Plethysmography, Spirometry
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Landon Pediatric Foundation
Smoking, Airway Obstruction
Effect of the Salbutamol on Mechanical Properties of Respiratory System
The aim of this study is to assess the bronchodilator response of salbutamol on respiratory mechanics of healthy individuals, smokers and COPD with varying degrees of airway obstruction.
- Trial name
- NCT01521572
- Testing
- Salbutamol sulphate
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
COPD, Cystic Fibrosis
Hyperpolarized Noble Gas MR Imaging for Pulmonary Disorders
The purpose of this study is to test the efficacy of Hyperpolarized Helium-3 gas in MR imaging in COPD, asthmatics, CF and healthy volunteers.
- Conditions
- COPD, Cystic Fibrosis, Asthma, Healthy
- Trial name
- NCT00846573
- Testing
- Hyperpolarized Helium-3
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Pulmonary Disease, Chronic Obstructive, Pneumonia, Bacterial
Modulation of Steroid Immunosuppression by Alveolar Efferocytosis
The long-term goals of this study are (a) to understand the biological underpinnings for the increased incidence of community-acquired pneumonia in patients with chronic obstructive pulmonary disease (COPD) who are treated with…
- Trial name
- NCT03034642
- Testing
- Bronchoscopy with bilateral bronchoalveolar lavages
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Ann Arbor Healthcare System
Chronic Obstructive Pulmonary Disease
Activation of Apoptosis-related Receptors on Alveolar Macrophages
The aim is to understand whether activation of receptors involved in clearance of apoptotic cells will improve efferocytosis in COPD patients in vitro and whether generation of pro-inflammatory cytokines can be decreased in COPD…
- Trial name
- NCT04775394
- Testing
- Bronchoscopy
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Jens Hohlfeld
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