Clinical trials: Chronic Obstructive Pulmonary
COPD
Evaluation of Airway Gene Expression in COPD and Controlled Populations
To explore potential proteins that may be used to develop novel therapies for COPD. This will be accomplished by acquiring material from the lower respiratory tract via endobronchial brushings.
- Trial name
- NCT00571792
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy, Pulmonary Disease, Chronic Obstructive
Relative Bioavailability of of Olodaterol and Ketoconazole
This clinical trial is intended to investigate a possible effect of the p-gp inhibitor ketoconazole on the bioavailability of olodaterol
- Trial name
- NCT01153711
- Testing
- BI 1744, Ketoconazole
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Asthma COPD
Medication Adherence and Use of Inhaler Devices in Patients With Asthma or COPD
This study aims to evaluate the impact of a pharmacist-led intervention programme on medication adherence and use of inhaler devices on clinical outcomes of patients with asthma and COPD attending a tertiary health facility in…
- Trial name
- NCT06417931
- Testing
- Patient education and counselling
- Where
- Nigeria
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
COPD, Aging
Vitamin D Supplementation and WBV in Inflammatory Markers, Strength and Body Composition in Old Patients With COPD
Verify the influence off vitamin D supplementation and a whole body vibration (WBV) protocol during 03 months in older patients chronic obstructive pulmonary disease
- Trial name
- NCT03684330
- Testing
- Vitamin D, whole body vibration (WBV)
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Maíra F Pessoa
Lung Diseases
Glottic Width and Respiratory Flow in Patients With Various Lung Diseases
In this study the investigators examine the glottic width and the respiratory flow at rest in patients with various lung disease.
- Trial name
- NCT02460757
- Testing
- Laryngoscopy
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Hospital, Essen
COPD
Complexity of the Airflow in COPD
Recently, there has been a growing interest in the study of nonlinear dynamics as a methodology for complementary analysis to characterize the respiratory pattern. These methods are well established in studies of heart rate.
- Trial name
- NCT01888705
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Hypertension, Diabetes Mellitus
Generative AI for Medication Counselling and Adherence in Community Pharmacies
Medication counseling within community pharmacies is crucial for managing chronic diseases, yet significant challenges regarding correctness and completeness remain in Jordan.
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemias, Cardiovascular Diseases
- Trial name
- NCT07649577
- Testing
- pharmacist-supervised AI-assisted medication counseling
- Where
- Jordan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Petra
COPD, Asthma
A Study Into Airways Disease Case Finding and Management
Chronic Obstructive Pulmonary Disease (COPD) is a disease of the lungs which is generally caused by smoking tobacco. It is a largely preventable disease that causes severe and irreversible damage to the lungs.
- Trial name
- ASSIST (NCT03355677)
- Testing
- Case finding Clinic, At Risk Case Clinics, Usual Care
- Where
- United Kingdom
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Southampton
COPD, Healthy Subjects
To Assess the Safety, Tolerability, and Pharmacokinetics of AZD7624 in Healthy Volunteers and COPD Patients
This study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of multiple ascending doses of AZD7624 in healthy subjects and patients with chronic obstructive pulmonary disease.
- Trial name
- NCT01817855
- Testing
- AZD7624
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease, Healthy Volunteers
Understanding Balance Impairment in COPD
This study is an observational study investigating the mechanisms of balance problems in people with COPD and how COPD impacts them living their daily lives.
- Trial name
- NCT05984498
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Teesside University
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Pulmonary Disease, Chronic Obstructive
An Investigation of the Pharmacokinetics of GSK961081 and Fluticasone Propionate in Healthy Volunteers
In the current study GSK961081 and fluticasone propionate will be administered in a blended formulation from a single device and compared with GSK961081 and fluticasone propionate administered alone and concurrently.
- Trial name
- NCT01449799
- Testing
- GSK961081 800 microgram dose, Fluticasone Propionate 500 microgram dose, GSK961081 800 microgram and Fluticasone Propionate 500 microgram separately
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Incontinence
Pelvic Floor Exercises Versus Pilates on Urinary Incontinance in Chronic Obstructive Pulmonary Disease
The aim of the study is To compare between the effect of both pelvic floor and Pilates exercises on urinary incontinences in COPD patients.
- Trial name
- NCT06337240
- Testing
- Pelvic floor on COPD patients, Pilates exercises on COPD patients
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Depression, COPD
Prevalence and Predictors of Depression in COPD
Depression adversely affects quality of life in COPD patients, associated with higher rate of exacerbations, admissions and mortality. However, local prevalence rate of depression in geriatric COPD patients remains unknown.
- Trial name
- NCT02415140
- Testing
- Rate of depression
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Kwong Wah Hospital
Chronic Obstructive Pulmonary Disease (COPD)
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)
A prospective multi-center study to define the sensitivity and specificity of CAPTURE for identifying previously undiagnosed patients with clinically significant COPD in a broad range of primary care settings.
- Trial name
- CAPTURE (NCT03581227)
- Testing
- CAPTURE Tool
- Where
- 8 sites in United States
- Volunteers
- 4,679 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Chronic Obstructive Pulmonary Disease, Cardiovascular Disease
Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study
This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Disease, Lung Cancer
- Trial name
- NCT02076061
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lund University
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Asthma, Breast Cancer
Collaborative Self-Management Support in Chronic Conditions - Qualitative Study
The management of chronic conditions is a challenge for health systems worldwide, particularly in the context of an aging population, and requires urgent improvement of health services.
- Conditions
- Asthma, Breast Cancer, Stroke
- Trial name
- CoSMaS-ql (NCT03262428)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pulmonary Disease, Chronic Obstructive
COPD MSA 3 Regions: Epidemiology and Risk Factors of COPD in Rural Environment (BM3R)
The agricultural environment presents a unique profile in terms of epidemiology of pulmonary diseases. Certainly due to persistent exposure to organic particles, the prevalence of COPD is higher in farmers than in the general…
- Trial name
- BM3R (NCT03299907)
- Testing
- Spirometry
- Volunteers
- 5,263 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
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