Clinical trials: Chronic Obstructive Pulmonary Disease (COPD)
COPD, COPD Exacerbation Acute
ProAir Digihaler in COPD Disease Management: A Real World Study
A pilot study to explore the utilization of the TEVA ProAir Digihaler rescue medication use and inhalation parameters to identify disease deterioration to help in the management of COPD patients in clinical practice.
- Trial name
- NCT04821869
- Testing
- ProAir Digihaler, Digihaler
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pulmonary Research Institute of Southeast Michigan
COPD
Validity and Reliability of The Turkish Version of Assessment of Burden of COPD Scale
In our study, we aimed to evaluate the validity and reliability of the Turkish version of theAssessment of Burden of COPD (ABC) Scale.
- Trial name
- NCT03610659
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Bezmialem Vakif University
Chronic Obstructive Pulmonary Disease
The Anti-oxidant Effects of N-Acetylcysteine in Chronic Obstructive Pulmonary Disease (COPD)
Chronic obstructive pulmonary disease (COPD) is a condition defined as a disease state characterized by airflow limitation that is not fully reversible.
- Trial name
- NCT03956888
- Testing
- N-acetylcysteine
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Siriraj Hospital
Asthma Bronchiale, COPD
Bronchodilator Response in COPD and Asthma: Correlation Between Spirometry, IOS Indices, and Dyspnea Relief
A bronchodilator reversibility test is widely used in the diagnosis and management of obstructive lung diseases. Bronchodilators relieve symptoms in asthma and COPD.
- Conditions
- Asthma Bronchiale, COPD, Bronchodilation, Spirometry
- Trial name
- NCT07364188
- Testing
- Bronchodilator
- Volunteers
- 120 people
- Sponsor
- Allergi- og Lungeklinikken, Elsinore
Chronic Obstructive Pulmonary Disease
To Evaluate Effectiveness of Aclidinium Bromide/Formoterol Fumarate Dihydrate in Chronic Obstructive Pulmonary Disease
ASTUTE is a pragmatic open randomised 12-week multinational trial to evaluate the effectiveness of aclidinium bromide/formoterol fumarate dihydrate fixed-dose combination compared to standard of care bronchodilators in chronic…
- Trial name
- ASTUTE (NCT03181880)
- Testing
- Aclidinium bromide/formoterol fumarate combination, Standard of Care
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation
Primary Objective: To evaluate the efficacy of dupilumab administered every 2 weeks in patients with moderate or severe Chronic Obstructive Pulmonary Disease (COPD) as measured by Annualized rate of acute moderate or severe COPD…
- Trial name
- NOTUS (NCT04456673)
- Testing
- Dupilumab SAR231893, Inhaled Corticosteroid, Inhaled Long-Acting Beta Agonist
- Where
- 334 sites in United States, Argentina and 27 more
- Volunteers
- 935 people
- Sponsor
- Sanofi
Role of Frailty in COPD
Influence of Frailty on Cardiovascular Events and Mortality in Patients With COPD.
Observational study on the influence of frailty on cardiovascular risk in COPD.
- Trial name
- FrCVCOPD (NCT05922202)
- Testing
- Assessment of cardiovascular events, cardiovascular mortality, all-cause mortality, and mortality due to COPD at 12 and 24 months
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Chronic Obstructive Pulmonary Disease
Evaluate the Safety Profile of BGF MDI in Chinese Patients With COPD in Routine Clinical Practice
This study is an observational, multicenter, prospective, single arm study. The objective of this study is to evaluate the safety of Breztri® Aerosphere® in Chinese patients with COPD in real world clinical practice.
- Trial name
- TORES (NCT04536402)
- Where
- 40 sites in China
- Volunteers
- 3,520 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease
Evaluation of Consumption of Sevoflurane in Chronic Obstructive Pulmonary Disease Patients
All the Patients undergoing General Anesthesia and the patients who are having Chronic Obstructive Pulmonary Disease will be considered for this study.
- Trial name
- SevoCOPD (NCT06108973)
- Testing
- Capnography
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Employee's State Insurance Corporation, New Delhi
Cystic Fibrosis, COPD
High Resolution Micro OCT Imaging
The purpose of this study is to learn about using the imaging to make images of the lungs and nose with the long-term goal of the research leading to potential treatments and new therapies for patients with cystic fibrosis.
- Conditions
- Cystic Fibrosis, COPD, PCD - Primary Ciliary Dyskinesia, Covid19
- Trial name
- NCT03256773
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
COPD
Impact of Ibis on Patients With Advanced COPD
The purpose of this research is to determine if Ibis™, a digital therapeutics solution developed by Senscio Systems, reduces the emergency room visits and hospitalizations of patients with COPD.
- Trial name
- NCT03131622
- Testing
- Digital Therapeutics
- Volunteers
- 240 people
- Sponsor
- Senscio Systems
Copd, Smoking
Clinical Features of Smoker Patients With Chronic Obstructive Pulmonary Disease
Smoking is the most important factor in the etiology of COPD. Some of the patients with COPD continue to smoke despite knowing this situation or they cannot quit even if they want.
- Trial name
- NCT04711629
- Testing
- Clinical Tests
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Chronic Obstructive Pulmonary Disease
Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient (FORSYYN)
Primary Objective To demonstrate that CHF 1535 pMDI is non-inferior to Symbicort® Turbohaler® in terms of pulmonary function (change from baseline in pre-dose morning FEV1 at Week 24) in patients with COPD.
- Trial name
- FORSYYN (NCT03888131)
- Where
- 53 sites in China
- Volunteers
- 750 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Copd
Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD
In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the…
- Trial name
- COPD (NCT06510686)
- Testing
- İnspiratory muscle training, Core training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Mustafa Ertuğrul Yaşa
Chronic Obstructive Pulmonary Disease, Type II Diabetes
Mobile Unit Screening of Pathologies Associated With Chronic Diseases - Feasibility
The main objective of this study is to assess the feasibility of standardized screening for comorbidities among patients with one or more of three chronic diseases (diabetes, COPD, atherosclerosis) by a mobile unit at times and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Type II Diabetes, Atherosclerosis
- Trial name
- DéProPAss (NCT02214056)
- Testing
- Patient recruitment, Mobile team exam
- Where
- 13 sites in France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Obstructive Pulmonary Disease
The Effect of Indacaterol on Exercise Endurance in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
This study compared the effect of indacaterol (300 μg once daily [od]) on exercise endurance with that of placebo in patients with moderate to severe chronic obstructive pulmonary disease.
- Trial name
- NCT00620022
- Testing
- Indacaterol 300 μg
- Where
- 20 sites in United States, Belgium and 4 more
- Volunteers
- 90 people
- Sponsor
- Novartis
Chronic Bronchitis
Feasibility Study of the Pulsed Electric Field Ablation System in Treating Chronic Bronchitis
To preliminarily evaluate the safety and feasibility of the pulsed electric field ablation system independently developed by Zhouling (Shanghai) Medical Appliance Co., Ltd. in the treatment of chronic bronchitis.
- Trial name
- NCT05771129
- Testing
- Pulse electric field ablation system developed by Zhouling (Shanghai) Medical Appliance Co., Ltd.
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Jiayuan Sun
COPD
Prevalence of Respiratory Aspiration in Patients With COPD
The aim of the study is to estimate the prevalence of respiratory aspiration in patients with COPD, in a tertiary hospital of Buenos Aires.
- Trial name
- NCT02722629
- Testing
- FEESST
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital Italiano de Buenos Aires
COPD
Feasibility of Noninvasive Trigeminal Nerve Stimulation During Exercise
The purpose of this study is to examine 1) effects of cutaneous electrical trigeminal nerve stimulation (eTNS) on respiratory control in healthy volunteers and 2) explore the potential of this approach to mitigate dyspnea in…
- Trial name
- NCT07686302
- Testing
- Active Stimulation, Fan therapy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
COPD
Feasibility of Dance in People With COPD
Despite the benefits associated with individuals with chronic obstructive pulmonary disease (COPD) engaging in pulmonary rehabilitation (PR) programs, the benefits diminish by 6 months.
- Trial name
- NCT03636594
- Testing
- Dance
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- West Park Healthcare Centre
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