Clinical trials: Chronic Orofacial Pain
Orofacial Pain, Facial Pain
Feasibility Testing of the "Face-Forward-Web" Program for Chronic Orofacial Pain
The goal of this study is to conduct a feasibility open pilot study (N=Up to 20) with exit interviews to assess the feasibility, acceptability, and credibility of the study protocol and Face-Forward-Web; a web-based mind-body…
- Trial name
- NCT06754917
- Testing
- Face-Forward-Web
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
Orofacial Pain
Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Chronic Orofacial Pain
Patients affected by chronic orofacial pain represent an emergent medical problem due to the lack of knowledge on the cause, pathophysiology and psychology of many of these conditions, that belongs to a multifactorial origin.
- Trial name
- NCT01883245
- Testing
- real tDCS
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Chronic Primary Orofacial Pain (CPOP), Persistent Idiopathic Facial Pain (PIFP)
An Innovative Cognitive-Behavioral Treatment For Chronic Orofacial Pain
Use these resources to provide understandable information about this study to patients, families, and health care providers: The present randomized clinical trial (RCT), conducted at the IRCCS Carlo Besta Neurological Institute…
- Trial name
- FACE-PRT (NCT07123233)
- Testing
- Pain Reprocessing Therapy, Usual Therapy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Chronic Orofacial Pain, Temporomandibular Disorder (TMD)
Orofacial Pain Self-management: Personality Moderation Effect
The objective of this clinical trial is to study the effect of self-management on pain perception in patients with chronic orofacial pain and temporomandibular disorders (TMD) comparing it with the conventional treatment proposed…
- Conditions
- Chronic Orofacial Pain, Temporomandibular Disorder (TMD), Temporomandibular Disorders (TMD), Temporomandibular Dysfunction (TMD)
- Trial name
- NCT06932406
- Testing
- Self-management intervention, Clinical Practice Guideline Intervention
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Temporomandibular Disorders, Psychological Distress
How Dentists' Personality Traits Affect Communication and Treatment Outcomes in TMD Patients
This prospective, longitudinal study investigates the influence of dentists' personality traits on patient-reported outcomes among individuals with temporomandibular disorders (TMDs) undergoing splint therapy.
- Conditions
- Temporomandibular Disorders, Psychological Distress, Chronic Orofacial Pain
- Trial name
- TMD (NCT07074366)
- Testing
- Splint Therapy with Structured Communication
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Chronic Pain
Emotional Intelligence and Chronic Orofacial Pain
Chronic pain, lasting more than three months, is a widespread health issue that negatively impacts daily life, leading to significant emotional distress and functional impairment.
- Trial name
- IEDOF (NCT07280338)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle
Occlusal Equilibration vs. Sham Therapies for TMDs: Post-Trial Follow-up (OEST)
Chronic temporomandibular disorders (TMDs) affect the masticatory muscles, the temporomandibular joints (TMJs), and associated structures. Except in cases of trauma, their etiology remains uncertain, debated, and multifactorial.
- Conditions
- Temporomandibular Disorders (TMD), Myalgia of Mastication Muscle, Arthralgia Syndrome
- Trial name
- OEST (NCT07445516)
- Where
- 2 sites in Spain
- Volunteers
- 110 people
- Sponsor
- Urbano Santana Penin
Mindfulness, Chronic Pain
Efficacy of Mindfulness Therapy in Orofacial Chronic Pain
Psychological impairments have a significant role in management and coping of pain in patients with orofacial pain disorders. The response of this kind of pathologies to topical or systemic medications is not predictable and…
- Conditions
- Mindfulness, Chronic Pain, Orofacial Pain
- Trial name
- NCT04765007
- Testing
- mindfulness-based stress reduction, Minimal intervention
- Volunteers
- 40 people
- Sponsor
- University of Jaén
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela
Facial Pain
Transcranial Magnetic Stimulation (TMS) for Trigeminal Neuralgia
The primary objective is to establish the feasibility of using TMS for COFP pain management in the interim period before surgery.
- Trial name
- TGN (NCT04120129)
- Testing
- TMS
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Carilion Clinic
Temporomandibular Disorders
Additional Effect of Pain Neuroscience Education to Orofacial and Neck Exercises in Temporomandibular Disorders
The objective of this study will be to verify the additional effect of Pain Neuroscience Education program to orofacial manual therapy and orofacial and neck motor control exercises for pain intensity and disability and for the…
- Trial name
- NCT03926767
- Testing
- Pain Neuroscience Education (PNE), Orofacial Manual Therapy, Orofacial Exercises
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- University of Sao Paulo
Temporomandibular Joint Disorders, Orofacial Pain
Individualized Assessment and Treatment for TMD
Temporomandibular/orofacial pain disorders (TMD) are a group of painful conditions with multiple determinants.This proposal has two main goals: 1) to test a highly individualized, adaptive treatment for TMD that has potential to…
- Trial name
- TMD3c (NCT04376333)
- Testing
- Cognitive-Behavioral Treatment, Individualized Assessment and Treatment Program, Standard Conservative Care
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- UConn Health
Myofascial Pain, Temporomandibular Disorders
Study on the Effect of Granisetron on Myofascial Pain in the Orofacial Muscles
The aim of this study is to to investigate if local treatment with intramuscular injections of granisetron are effective in alleviating pain in patients with chronic myofascial pain in the orofacial muscles The study hypothesis…
- Trial name
- NCT02230371
- Testing
- Granisetron
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Neuropathic Pain, Orofacial Pain
Bilateral TMS vs. Unilateral TMS
Rationale: In 2016, Henssen et al. discuss that orofacial pain may be conducted in a bilateral fashion, inducing activation of both thalami [1].
- Conditions
- Neuropathic Pain, Orofacial Pain, Trigeminal Neuropathy
- Trial name
- biTMSvsuniTMS (NCT03710967)
- Testing
- Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Radboud University Medical Center
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Facial Pain, Temporomandibular Joint Disorder
Diagnosis and Evaluation of Patients Needing Third Molar (Wisdom Tooth) Extraction and Patients With Chronic Facial Pain
This study provides a mechanism for evaluating patients for possible participation in NIDCR clinical research studies. NIDCR studies involve three major areas-pain, neurosensory mechanisms, and pain-relieving drugs-all of which…
- Trial name
- NCT00001600
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)