Clinical trials: Chronic Persistent Surgical Pain
Breast Cancer, Surgery
Analgesic Effect of Resistance Training for Breast Cancer Survivors
Persistent pain after treatment for breast cancer is a major clinical problem, affecting 25-60 % of the patients and is a source of considerable physical disability and psychological distress.
- Conditions
- Breast Cancer, Surgery, Chemotherapy Effect, Radiotherapy Side Effect
- Trial name
- (ANTRAC) (NCT04509284)
- Testing
- Training, Control
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University
Chronic Postsurgical Pain, Acute Postoperative Pain
Persistent Pain and Its Impact on Daily Life After Lung Surgery
This study will examine how pain changes over the first six months after lung surgery and how it affects daily life. It will include adults scheduled for surgery to remove part or all of a lung.
- Conditions
- Chronic Postsurgical Pain, Acute Postoperative Pain, Pain-Related Functional Interference
- Trial name
- NCT07853456
- Testing
- Longitudinal Assessment of Pain and Pain-Related Functional Interference
- Volunteers
- 350 people
- Sponsor
- Aerospace Center Hospital
Breast Cancer, Chronic Pain
Persistent Post-Surgical Pain in Women With BrCA
Women with early-stage breast cancer (BrCA) are surviving longer, but many experience symptoms after curative treatments. Approximately 50% of BrCA survivors experience persistent pain post-surgery.
- Trial name
- NCT02266082
- Testing
- No intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Florida
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Neuropathic Pain, Thoracic Surgery, Video Assisted
Chronic Pain After Thoracotomy (Video Assisted Thoracic Surgery - VATS)
This is an explorative study investigating potential nerve injury after VATS.
- Conditions
- Neuropathic Pain, Thoracic Surgery, Video Assisted, Chronic Pain
- Trial name
- NCT01068457
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Opioid Use, Post Operative Pain
Assessment of the Development of Postoperative Persistent Postoperative Pain
During the postoperative period, it is possible to observe the development of acute pain, which lasts no longer than a week after surgery.
- Conditions
- Opioid Use, Post Operative Pain, Chronic Pain
- Trial name
- NCT05370924
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Patients Scheduled for Thoracic Surgery/Esophagectomy Will be Enrolled, Persistent Post Surgical Pain
The Emerging Role of Resolvins in the Prevention of Chronic Pain After Thoracic Surgery
The aim of the study is to investigate whether pre-operative dysregulated systemic lipid mediator pathways are associated with increased risk for the development of persistent post surgical pain.
- Trial name
- NCT03095157
- Testing
- fractionated marine lipid concentrate derived from anchovy and sardine oil
- Volunteers
- 80 people
- Sponsor
- Brigham and Women's Hospital
Lung Cancer
Sensory Mapping and Thermal Thresholds After Thoracic Surgery
The study will investigate topography of sensory changes late after lung cancer surgery
- Trial name
- NCT01274858
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Chronic Post-Procedural Pain
The Effects of Anesthetics on Persistent Pain Following Breast Cancer Surgery
Persistent postoperative pain occurs up to 25 to 60 % after mastectomy. This occurs at a higher frequency than the rate of invasive surgery.Therefore, many ways have been tried to study risk factors.
- Trial name
- NCT03782896
- Testing
- acute postoperative pain
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
Persistent Post-surgical Pain
Yoga for Persistent Post-Surgical Pain (PPSP)
The overall goal of this project is to complete a pilot feasibility randomized controlled trial (RCT) to inform a future fully-powered translational study evaluating yoga for management and resolution of persistent-post surgical…
- Trial name
- NCT06949007
- Testing
- Yoga, Chronic Pain Health Education
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Inguinal Hernia, Chronic Pain
A National Center for Persistent Severe Pain After Groin Hernia Repair
This prospective, consecutive cohort study presents nationwide 5-year outcome data on patients with severe persistent pain after groin hernia repair (SPG).
- Trial name
- Q5Y (NCT03713047)
- Volunteers
- 222 people
- Sponsor
- University of Copenhagen
Chronic Post-Procedural Pain, Breast Cancer
Evaluation of Persistent Postsurgical Pain After Breast Surgery With a Pectoral Nerves Block (Pecs) Type II
Background and objectives The Pectoral Nerves Block (Pecs) Type II is a regional anesthesia technique that provides post-surgical pain relief for patients undergoing breast surgery.
- Trial name
- NCT03116048
- Testing
- Chronic pain evaluation
- Where
- Belgium
- Volunteers
- 121 people
- Sponsor
- GZA Ziekenhuizen Campus Sint-Augustinus
Post-mastectomy Pain Syndrome, Breast Cancer
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months…
- Conditions
- Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04874038
- Testing
- Lidocaine 20mg/ml
- Where
- 17 sites in Canada, Nepal and 1 more
- Volunteers
- 1,604 people
- Sponsor
- University Health Network, Toronto
Chronic Post Operative Pain
Cytokine Alterations and Chronic Post-Surgical Pain
Chronic Post-Surgical Pain (CPSP) is a condition that involves experiencing pain and/or discomfort that lasts for more than 3 months following surgery without any explainable cause of this pain such chronic infection or pain…
- Trial name
- NCT06418295
- Testing
- Unilateral thoracotomy
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Pain
Algovita Spinal Cord Stimulation System Hi-Fi Study
The objective of this study is to obtain post-market clinical outcome data for the Algovita SCS System when used on-label, according to the applicable directions for use, using high fidelity tonic stimulation at either ultra-high…
- Trial name
- NCT03622866
- Testing
- Ultra-high pulse width stimulation, Traditional pulse width stimulation
- Where
- 10 sites in United States
- Volunteers
- 20 people
- Sponsor
- Nuvectra
Cancer-related Pain, Chronic Post Cancer Surgery Pain
Exploring the Link Between Cancer Genetics and PPSP
Pain is common in cancer, affecting between 40 and 60% of patients depending on tumour type and stage of disease, and represents a major area of unmet need in cancer survivors.
- Conditions
- Cancer-related Pain, Chronic Post Cancer Surgery Pain, Breast Cancer
- Trial name
- NCT04007861
- Volunteers
- 104 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome
Persistent Post-Lumbar Surgery Pain Syndrome (PSPS) Type II is a Common Condition Encountered in Pain Units, With Limited Available Therapeutic Options. Epidural Pulsed Radiofrequency (PRF) Administered Via Catheter Has Demonstrated Greater Efficacy Compared to the Transforaminal Approach. This Rand
This study is for people who continue to have low back pain after spinal surgery, a condition called persistent spinal pain syndrome type II. Current treatments, such as epidural injections, often provide only limited relief.
- Conditions
- Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome, Chronic Low Back Pain, Post-Laminectomy Syndrome
- Trial name
- EPIPUL (NCT07156513)
- Testing
- Epidural Pulsed Radiofrequency, Betamethasone (Epidural Corticosteroid Injection)
- Where
- 4 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Puerta de Hierro University Hospital
Endometriosis, Pelvic Pain
Endometriosis and Chronic Endometritis
Pelvic endometriosis is a complex estrogen-dependent inflammatory syndrome of unknown etiology, altering the microenvironment of the peritoneal cavity and probably endometrial receptivity, and adversely affecting the…
- Conditions
- Endometriosis, Pelvic Pain, Infertility
- Trial name
- NCT05824507
- Testing
- Endometrial aspiration biopsies for CE diagnosis
- Where
- Poland
- Volunteers
- 64 people
- Sponsor
- Jagiellonian University
Chronic Pain
Trigger-point Blockade in Persistent Pain After Laparoscopical Groin Hernia Repair
Groin hernia repair is a common procedure performed in approximately 2,000 patients per one million inhabitants. Severe chronic pain following groin hernia repair is seen in 2-5% of the patients indicating that a large number of…
- Trial name
- Trigger-lap (NCT02065804)
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- University of Copenhagen
Patients With Persistent Severe Pain After Groin Hernia Repair
Does Re-surgery Improve Somatosensory Outcomes in Persistent Pain After Groin Hernia Repair
Groin hernia repair is accompanied by persistent severe pain in 2-4% of the patients significantly restraining psychophysical functions.
- Trial name
- NCT05238571
- Testing
- Re-surgery
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- mads u werner