Clinical trials: Chronic Pulmonary Obstruction
Chronic Obstructive Pulmonary Disease (COPD)
Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD
The purpose of this study is to describe patients' clinical and self-reported outcomes of treatment with budesonide / glycopyrronium / formoterol Metered dose inhaler (BGF MDI) in Romania in real-life setting, up to 6 month of…
- Trial name
- COnCORD (NCT06368427)
- Testing
- budesonide / glycopyrronium / formoterol
- Where
- 16 sites in Romania
- Volunteers
- 10 people
- Sponsor
- AstraZeneca
Chronic Obstructive Pulmonary Disease Exacerbation
Mindfulness-based Interventions in COPD Patients
The purpose of this pilot study is to assess the feasibility of a brief digital mindfulness-based intervention for COPD patients and its effectiveness regarding the reduction of psychological distress as well as stress.
- Trial name
- SPIROMIND (NCT04769505)
- Testing
- digital mindfulness-based intervention (MBI)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Karl Landsteiner Institute for Lung Research and Pneumological Oncology
Pulmonary Disease, Chronic Obstructive
Spiriva® in Patients With Chronic Obstructive Pulmonary Disease (COPD)
As part of the post-marketing surveillance, information is to be gathered regarding the tolerance and efficacy of Spiriva® 18 micrograms in patients with COPD under conditions of daily practice
- Trial name
- NCT02172482
- Testing
- Tiotropium bromide
- Volunteers
- 63,127 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstuctive Pulmonary Disease
Lung Microbiome and Inflammation in Early COPD
This is a cross sectional case controlled study to assess lung microbiome and inflammation in smokers with and without Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- NCT02777879
- Testing
- Bronchoscopy
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- NYU Langone Health
COPD
Dose-Ranging Study in Patients With Chronic Obstructive Pulmonary Disease (COPD)
The trial is designed to identify an appropriate dose of QAB149 for delivery via a multiple dose inhaler for use in the COPD Phase III program.
- Trial name
- NCT00098228
- Testing
- QAB149
- Where
- 54 sites in United States
- Volunteers
- 686 people
- Sponsor
- Novartis Pharmaceuticals
Acute Exacerbation of COPD, Pulmonary Disease, Chronic Obstructive
Social Media-based Bundle Care of AECOPD Patients.
Chronic obstructive pulmonary disease(COPD) is an incompletely reversible and progressive pulmonary disease characterized by airflow restriction, which is the third leading cause of death worldwide, accounting for 6% of all…
- Conditions
- Acute Exacerbation of COPD, Pulmonary Disease, Chronic Obstructive, COPD, Lung Diseases, Obstructive
- Trial name
- NCT05209607
- Testing
- Mobile Medical and bundle management, Mobile Medical and standard of care
- Volunteers
- 648 people
- Sponsor
- Beijing Chao Yang Hospital
Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema
Volumetric HRCT in Stable COPD Patients.
This study evaluates the role of volumetric high-resolution computed tomography (HRCT) of the chest in assessing patients with stable chronic obstructive pulmonary disease (COPD).
- Conditions
- Chronic Obstructive Pulmonary Disease, Pulmonary Emphysema, Airway Obstruction
- Trial name
- NCT07809399
- Testing
- Volumetric HRCT chest, Spirometry and Body Plethysmography
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Pulmonary Disease, Chronic Obstructive, Heart Failure, Systolic
Inspiratory Muscle Training for Breathless Patients With Chronic Obstructive Pulmonary Disease and Heart Failure
The purpose of this study is to determine whether inspiratory muscle training is effective to improve breathless and exercise intolerance in symptomatic patients with chronic obstructive pulmonary disease (COPD) plus chronic…
- Trial name
- NCT02579200
- Testing
- POWERbreathe®KHA (IMT group)
- Where
- 3 sites in Belgium, Brazil
- Volunteers
- 50 people
- Sponsor
- Queen's University
Asthma, Chronic Obstructive Pulmonary Disease
Towards Restoring the Physiological Inhibition of Airway Narrowing in Asthma
Asthma and COPD are characterized by airway narrowing. The most potent, physiological mechanism leading to bronchodilation is taking a deep inspiration.
- Trial name
- NCT00279136
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Hypertension, Pulmonary, Pulmonary Disease, Chronic Obstructive
Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension: Prevalence and Quality of Life
The purpose of this study is to determine the prevalence of pulmonary hypertension (PH) among patients suffering from Chronic Obstructive Pulmonary Disease (COPD) and to assess the quality of life in those patients with…
- Trial name
- NCT01423071
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- Wissenschaftliches Institut Bethanien e.V
Chronic Obstructive Pulmonary Disease
A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease
The purpose of this study is to evaluate the influence of exercise capacity and safety of iNO at doses of 10 ppm or 40 ppm for 2 hours per day after continuous treatment for one week, which is of great significance for finding…
- Trial name
- NOVEL (NCT05896800)
- Testing
- Inhaled nitric oxide (NO), air
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Chronic Obstructive Pulmonary Disease
Effect of Remote Physiologic Monitoring (RPM) on Outcomes in COPD Patients
This pre/post study was a retrospective analysis of unplanned hospitalization rates in a cohort of COPD subjects started on remote physiologic monitoring (RPM) at a large, outpatient pulmonary practice.
- Trial name
- NCT05518981
- Testing
- Respiratory Remote Patient Monitor (Spire Health Tag)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Spire, Inc.
Chronic Obstructive Pulmonary Disease
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Nebulized Ensifentrine in Healthy Chinese Subjects
This is a phase 1, open-label, parallel cohort study to evaluate the PK, safety and tolerability of nebulized ensifentrine following administration of single and multiple doses in healthy Chinese male subjects.
- Trial name
- NCT05758428
- Testing
- Ensifentrine
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nuance Pharma (shanghai) Co., Ltd
Sleep Hygiene, Sarcopenia
Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease
We aim to clarify the relationship between sleep hygiene and the onset of sarcopenia or cognitive dysfunction using sleep time, arousal, and sleep quality as indicators in COPD or IPF patients, and clarify the effects of sleep…
- Conditions
- Sleep Hygiene, Sarcopenia, Cognitive Function, COPD
- Trial name
- NCT05193136
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- National Hospital Organization Minami Kyoto Hospital
Chronic Obstructive Pulmonary Disease, COPD
Lung Function and Patient Preference With QVA149 vs. Tiotropium in COPD Patients
The study is a multicenter, randomized, 2-period, open-label, two arm, cross-over study to show the superior effect of a 4 week treatment each with QVA149 versus tiotropium on lung function.
- Trial name
- FAVOR (NCT02125734)
- Testing
- QVA149, Tiotropium
- Where
- 18 sites in Germany
- Volunteers
- 88 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Obstructive Pulmonary Disease, Cardiovascular Diseases
An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study
This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.
- Conditions
- Chronic Obstructive Pulmonary Disease, Cardiovascular Diseases, Lung Cancer
- Trial name
- BIG3 (NCT01460264)
- Where
- Sweden
- Volunteers
- 10,000 people
- Sponsor
- Region Skane
COPD, Mortality
A Six Minute Walking Test Based Index as an Outcome Predictor in COPD Subjects. (Chronic Obstructive Pulmonary Disease)
The six minute walking test (6MWT) is a recognized clinical test to evaluate exercise capacity in different diseases and different conditions. The modalities of performance are described in International Guidelines.
- Conditions
- COPD, Mortality, Disease Exacerbation, Exercise Capacity
- Trial name
- COPD (NCT03799263)
- Testing
- evaluation group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Maugeri Foundation
Chronic Obstructive Pulmonary Disease, Emphysema
Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD
Studying the airway microenvironment in patients undergoing surgical and bronchoscopic interventions for COPD
- Conditions
- Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis
- Trial name
- COPD-ENVIRON (NCT03010592)
- Where
- 2 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Chronic Obstructive Pulmonary Disease
Slow Chest Compression on Dynamic Hyperinflation, Dyspnea and Peripheral Muscle Deoxygenation in Patients With COPD
Background: Commonly, patients with chronic obstructive pulmonary disease (COPD) present dyspnea, dynamic hyperinflation (DH) and important peripheral muscle deoxygenation when performing their activities of daily living (ADLs).
- Trial name
- NCT02746536
- Testing
- Slow chest compression, No slow chest compression
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of the State of Santa Catarina
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS)
Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation
To evaluate the safety and effectiveness of the Automatic Expiratory Positive Airway Pressure (Auto-EPAP) feature versus manual expiratory positive airway pressure (EPAP) in the Vivo 45 LS Ventilator.
- Conditions
- Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD)
- Trial name
- Vivo NOVA (NCT06560411)
- Testing
- Non-Invasive Ventilation
- Where
- 4 sites in United States
- Volunteers
- 23 people
- Sponsor
- Breas Medical, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.