Clinical trials: Chronic Venous Thrombosis
Deep Vein Thrombosis
Shear-Wave Elastography in Deep Vein Thrombosis
Compression ultrasonography (CUS), which is the gold-standard for the diagnosis of deep vein thrombosis, cannot provide adequate information on the timing of the onset of thrombosis.
- Trial name
- SWE-DVT (NCT06025591)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
May-Thurner Syndrome, Deep Vein Thrombosis
Venous Stent for the Iliofemoral Vein Investigational Clinical Trial Using the DUO Venous Stent System
This is a prospective, multi-center, single-arm, non-blinded clinical trial designed to investigate the safety and efficacy of the Vesper DUO Venous Stent System as compared to a pre-defined performance goal (PG) established from…
- Conditions
- May-Thurner Syndrome, Deep Vein Thrombosis, Chronic Venous Insufficiency
- Trial name
- VIVID (NCT04580160)
- Testing
- Duo Venous Stent System
- Where
- 30 sites in United States, Poland
- Volunteers
- 162 people
- Sponsor
- Vesper Medical, Inc.
Diabetic Macular Edema, Branch Retinal Vein Occlusion
Non-damaging Retinal Laser Therapy With PASCAL Laser for Macular Diseases
This trial seeks to prove the safety and efficacy of photothermal stimulation treatment to diabetic macular edema, chronic central serous retinopathy, macular edema secondary to branch retinal vein occlusion and macular…
- Conditions
- Diabetic Macular Edema, Branch Retinal Vein Occlusion, Chronic Central Serous Retinopathy, Macular Telangiectasia
- Trial name
- EPM (NCT01975103)
- Testing
- Topcon Endpoint Management
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of Rio Grande do Sul
Chronic Venous Disease, Chronic Venous Insufficiency, CVI
The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry
The goal of this observational study is to gather additional safety and performance (effectiveness) data on the device for the treatment of symptomatic lower extremity venous obstructions and occlusions.
- Conditions
- Chronic Venous Disease, Chronic Venous Insufficiency, CVI, Venous Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- CALIBER (NCT07529756)
- Testing
- Recanalization and debulking
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Intervene, Inc.
Vascular, DVT - Deep Vein Thrombosis
Outcomes of Iliac Vein Stenting With Dedicated Venous Stents in Treatment of Chronic Post-thrombotic Venous Ulcers
Outcomes of iliac vein stenting with dedicated venous stents in treatment of chronic post-thrombotic venous ulcers Deep vein thrombosis (DVT) affects 1 to 3 individuals per 1000 annually.
- Conditions
- Vascular, DVT - Deep Vein Thrombosis, Post Thrombotic Syndrome, Venous Ulcer of Leg
- Trial name
- NCT07762222
- Testing
- dedicated venous stenting, Dedicated venous stent / iliofemoral dedicated venous stenting
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis
Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System
The purpose of Case-Specific Health Care Professional (HCP) Clinical Survey of Liberant™ Thrombectomy System, also known as the Liberant Clinical Assessment, is to collect first-in-human clinical data to confirm the safety and…
- Conditions
- Venous Embolism of Lower Extremities (Diagnosis), Arterial Embolism and Thrombosis, Acute DVT of Lower Extremity, Chronic DVT of Lower Extremity
- Trial name
- NCT07335341
- Testing
- Liberant Thrombectomy System
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic Endovascular
Machine Learning, Chronic Obstructive Pulmonary Disease
Machine Learning-based Models in Prediction of DVT and PTE in AECOPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory system disease characterized by persistent respiratory symptoms and irreversible airflow restriction, which seriously endangers people's health.
- Conditions
- Machine Learning, Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified, Pulmonary Thromboembolisms
- Trial name
- NCT05905874
- Testing
- Machine learning-based prediction model
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- West China Hospital
Heart Failure, Chronic Obstructive Pulmonary Disease
Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study
This is a multicentric, prospective, observational study with two cohorts and adjunctive procedure. It aims at collecting and analyzing data about the function of an innovative hospital-territory integration health service for…
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Diabetes Mellitus, Pneumonia
- Trial name
- PRIME (NCT05723185)
- Testing
- Outpatient visit
- Where
- Italy
- Volunteers
- 246 people
- Sponsor
- Rovere Querini Patrizia
Chronic Venous Thrombosis, Venous Thrombosis Upper Extremity
Surfacer System to Facilitate Access in Venous Occlusions
Prospective, single-arm, multicentre, international Registry of the Surfacer System for the treatment of patients with limited or diminishing upper body venous access or pathology impeding standard access methods.The purpose of…
- Conditions
- Chronic Venous Thrombosis, Venous Thrombosis Upper Extremity, Venous Thrombosis Upper Extremity Superficial Veins
- Trial name
- SAVE (NCT02875899)
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 30 people
- Sponsor
- Merit Medical Systems, Inc.
Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization
Duration and Adverse Events of Non-cuffed Catheter in Patients With Hemodialysis
The duration and adverse events of non-cuffed catheter in patients with hemodialysis will be investigated by multicenter prospective cohort.
- Conditions
- Renal Failure Chronic Requiring Hemodialysis, Central Venous Catheterization, Inadequate Hemodialysis Blood Flow, Venous Stenosis
- Trial name
- DACAPO (NCT02264964)
- Testing
- GamCath®, Arteriovenous fistula creation
- Volunteers
- 1,400 people
- Sponsor
- Shanghai Changzheng Hospital
Deep Vein Thrombosis, Chronic Portal Vein Thrombosis
Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis.
Open randomized therapeutic study to assess the efficacy of Xarelto 15mg/day in the recurrence of thromboembolic event compared to an untreated group in patients with chronic portal vein thrombosis without high risk thrombophilia.
- Trial name
- RIPORT (NCT02555111)
- Testing
- Xarelto
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Cirrhosis
Comparison of Three Transfusion Strategies for Central Venous Catheterization in Cirrhotics: A Randomized Clinical Trial
The aim of this study is to compare three different blood transfusion strategies for coagulopathy correction before central venous catheterization in patients with chronic liver failure (cirrhosis and/or chronic liver graft…
- Trial name
- POCKET (NCT02311985)
- Testing
- Coagulogram-based protocol, Thromboelastometry-based protocol, Restrictive strategy
- Where
- Brazil
- Volunteers
- 57 people
- Sponsor
- Hospital Israelita Albert Einstein
Post Thrombotic Syndrome, Deep Vein Thrombosis
Long-term Outcome After Heparin and Edoxaban Versus Heparin Plus Vit K Antagonists for Acute DVT and PE
Centers that participated in the HOKUSAI VTE trial will be invited to collect follow of previously enrolled patients at least 2 years after the index VTE.
- Conditions
- Post Thrombotic Syndrome, Deep Vein Thrombosis, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT03757481
- Testing
- no intervention
- Where
- 11 sites in France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Deep Vein Thrombosis, Compression Ultrasound
A New Technique to Diagnose Acute and Chronic Deep Vein Thrombosis
In clinical practice, compression ultrasound (CUS) has become an easy and reliable noninvasive tool for the diagnosis of deep vein thrombosis (DVT).
- Conditions
- Deep Vein Thrombosis, Compression Ultrasound, Elastography, Elasticity Imaging Techniques
- Trial name
- NCT02809638
- Testing
- ultrasound elastography
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale ASL 6, Livorno
Pulmonary Embolism, Chronic Obstructive Pulmonary Disease
Pulmonary Embolism as a Cause of COPD Exacerbations
The primary objective is to demonstrate the clinical benefits of an active strategy for the diagnosis and treatment of PE compared to usual care in patients with unexplained exacerbations of COPD who require hospital admission.
- Trial name
- SLICE (NCT02238639)
- Testing
- Diagnostic and therapeutic strategy: Highly sensitive D-dimer testing and, if positive, multidetector computed tomographic pulmonary angiography (MDCT).
- Where
- 19 sites in Spain
- Volunteers
- 746 people
- Sponsor
- Ministry of Health, Spain
Deep Vein Thrombosis, Post-thrombotic Syndrome
Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System
To evaluate the efficacy of ultrasound accelerated thrombolysis using the EkoSonic® Endovascular System with standard infusion of thrombolytic drug for post-thrombotic syndrome from chronic venous occlusion.
- Trial name
- ACCESS PTS (NCT02159521)
- Testing
- EkoSonic® Endovascular System, Alteplase
- Where
- 22 sites in United States
- Volunteers
- 81 people
- Sponsor
- Boston Scientific Corporation
Venous Ulcer, Venous Stasis Ulcer
Safety and Efficacy Trial of HP802-247 in the Treatment of Chronic Venous Leg Ulcers
This study is being done to find out if an investigational product called HP802-247 can help people with venous leg ulcers. Investigational means that HP802-247 has not been approved by the U.S.
- Conditions
- Venous Ulcer, Venous Stasis Ulcer, Ulcer
- Trial name
- NCT01853384
- Testing
- HP802-247, HP802-247 Vehicle
- Where
- 46 sites in Belgium, Czechia and 3 more
- Volunteers
- 252 people
- Sponsor
- Healthpoint
Post-thrombotic Syndrome
Bern Venous Stent Registry
The purpose of this study is to examine patency rates of self-expanding nitinol stents for treatment of iliofemoral and inferior vena cava residual thrombosis, obstruction or stenosis.
- Trial name
- NCT02433054
- Testing
- CE-certified dedicated venous stents
- Where
- Switzerland
- Volunteers
- 548 people
- Sponsor
- University of Zurich
Renal Insufficiency, Chronic, Deep Venous Thrombosis, Protection Against
Study of the Bioaccumulation of Tinzaparin in Renally Impaired Patients When Given at Prophylactic Doses
The purpose of this study is to assess if accumulation of anti-Xa activity occurs after repeated daily administration of prophylactic doses of tinzaparin in patients with severe chronic kidney disease (CKD) requiring…
- Trial name
- STRIP (NCT02719418)
- Testing
- Tinzaparin
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Maisonneuve-Rosemont Hospital