Clinical trials: Chronic Wound
Lateral Epicondylitis
Comparison of Muscle Energy Technique and Oscillating Energy Manual Therapy in Chronic Lateral Epicondylitis
Lateral epicondylitis (LE) is a painful musculoskeletal condition caused by overuse. The condition is also called tennis elbow because it affects 50% of tennis players, notably beginners learning the one-handed backhand.
- Trial name
- NCT05354167
- Testing
- muscle energy technique, oscillating manual energy therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Stress Disorders, Post-Traumatic
Intensive Treatment for Chronic Pain and Posttraumatic Stress Disorder (PTSD)
This study is investigating the efficacy of an intensive (3 week) integrated treatment for Veterans with both pain and PTSD.
- Trial name
- NCT01120067
- Testing
- Intensive Treatment, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- VA Office of Research and Development
Tendinopathy
Minimal Invasive Treatment of Achilles Tendinopathy: Focus on Percutaneous Release (Maffulli)
To evaluate the outcome of percutaneous paratenon release for chronic midportion Achilles tendinopathy.
- Trial name
- NCT04793971
- Testing
- percutaneous paratenon release
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Pulmonary Disease
Inhaled Nitric Oxide to Prevent and Treat Bronchopulmonary Dysplasia
Inhaled nitric oxide in preterm babies with respiratory failure or ventilator dependence will: 1. decrease the incidence of Bronchopulmonary Dysplasia (BPD) or death 2.
- Trial name
- NO-BPD (NCT01503801)
- Testing
- Nitric Oxide, respiratory support
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fudan University
Spinal Cord Injuries
Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury
The purpose of this research is to learn about how the participant's body is able to balance changes in blood pressure, and how spinal cord stimulation affects these changes as well as immune \& cardiovascular function in…
- Trial name
- NCT07210411
- Testing
- Tests of sympathetic inhibition, Tests of above level sympathetic activation, Testing of below level sympathetic activation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Chronic Pain, Trauma
Influence of Trauma on Pain Area and Widespreadness in Chronic Pain Patients
It is well known that patients suffering from chronic pain report higher levels of pain, anxiety, and depression if they have experienced a traumatic event. However, little is know about pain area and widespreadness.
- Trial name
- NCT05190367
- Where
- Germany
- Volunteers
- 914 people
- Sponsor
- Hannover Medical School
Pain, Inflammatory Response
Association Between Body Composition and Pain in Spinal Cord Injury
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and…
- Trial name
- NCT05459207
- Testing
- Moderate Fat Meal, High Fat Meal
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic
Effect of Mental Imagery in Patients With Persistent Post-concussion Symptoms
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic, Post Traumatic Headache
- Trial name
- NCT07166536
- Testing
- Provocation Test for Symptoms Using Mental Imagery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital
Chronic Subdural Hematomas
PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial
This is a prospective, randomized, controlled, open-label, blinded endpoint (PROBE) clinical investigation in which patients with non-emergent chronic subdural hematoma (cSDH) requiring treatment will be randomized (1:1) to…
- Trial name
- PHILFIRST (NCT07576998)
- Testing
- PHIL™ (Precipitating Hydrophobic Injectable Liquid), Surgical evacuation
- Volunteers
- 475 people
- Sponsor
- Microvention-Terumo, Inc.
Acute Kidney Injury, Kidney Transplant
MEMRI and Kidney Disease
Acute kidney injury (AKI) is common and costly.1 Although patients who suffer an episode of AKI may recover, many will go on to develop cardiovascular disease and chronic kidney disease (CKD).
- Conditions
- Acute Kidney Injury, Kidney Transplant, Vasculitis, Chronic Kidney Disease(CKD)
- Trial name
- NCT06698614
- Testing
- MRI, Blood tests, Urine tests
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Edinburgh
Spinal Cord Injury, Chronic Neuropathic Pain
VIRTUAL WALKING AND TRANSCRANIAL DIRECT CURRENT STIMULATION FOR CHRONIC NEUROPATHIC PAIN DUE TO SPINAL CORD INJURY
The goal of this feasibility study is to assess the feasibility of the combined treatment intervention "virtual walking (VW) and transcranial direct current stimulation (tDCS)" of neuropathic pain in patients with spinal cord…
- Trial name
- NCT06710808
- Testing
- Virtual walking and transcranial direct current stimulation
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Tendinopathy, Jumper's Knee
A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
The study is a 12-week human study where 60 participants with chronic patellar tendinopathy (more than 3 months symptoms duration) are randomised to undergo 12 weeks of targeted resistance exercise either in the morning or in the…
- Trial name
- TENDOTIME (NCT06217432)
- Testing
- Resistance training for knee extensors
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Whiplash Associated Disorders, WAD
Neuromuscular Mechanisms Underlying Poor Recovery From Whiplash Injuries
This study is investigating whether changes in the shape and size of bodily muscles and spinal cord anatomy can influence recovery rates following a motor vehicle collision (MVC).
- Conditions
- Whiplash Associated Disorders, WAD, Whiplash
- Trial name
- NCT02157038
- Testing
- Pedometer, MRI
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Northwestern University
Wounds
Evaluation of Wound Biofilm in Acute and Chronic Wounds
Patients who present to a wound care center for management of their wounds will be evaluated clinically to establish if their wounds are chronic or acute. These patients will undergo standard of care management of their wounds.
- Trial name
- NCT00764348
- Testing
- no treatment
- Sponsor
- Southwest Regional Wound Care Center
Tetraplegia, Asthma
Exhaled Breath Condensate Biomarkers of Inflammation in Individuals With Chronic Cervical Spinal Cord Injury
The purpose of this study is to obtain markers of airway inflammation from the exhaled breath condensate (the moisture in exhaled air) for comparison to blood based markers.
- Trial name
- NCT02235714
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Enterocolitis, Necrotizing, Bacteremia
Antibiotic "Dysbiosis" in Preterm Infants
Prolonged antibiotic use in preterm neonates has significant consequences on the developing intestinal microbiome, metabolome and host response, predisposing the neonate to various major morbidities, including necrotizing…
- Conditions
- Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage
- Trial name
- NCT02784821
- Testing
- Antibiotic, Gastric fluid, Breast milk
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Florida
Running-related Injuries, Medial Tibial Stress Syndrome
Machine Learning-Based Risk Identification and Precision Exercise for Common Running Injuries
This study aims to identify biomechanical risk factors associated with common running-related injuries in recreational runners using machine learning analysis.
- Conditions
- Running-related Injuries, Medial Tibial Stress Syndrome, Patellofemoral Pain, PFP, Chronic Achilles Tendinopathy
- Trial name
- NCT07689916
- Testing
- Multidimensional Precision Intervention, Precision Exercise Intervention
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Zeyi Zhang
Xerosis
Safety and Efficacy of SQIN™ on Xerosis in Adults With Mobility Problems and Paralysis
In the general population, xerosis is often caused by external factors such as seasonal changes. In that case, the best way to relieve dry skin is to use a standard moisturizer.
- Trial name
- NCT02429206
- Testing
- SQIN, standard moisturizing cream (Glaxal Base)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Nordic Life Science Pipeline Inc.
Chronic Traumatic Encephalopathy, Traumatic Encephalopathy
Tau And Connectomics In TES Study
This pilot study aims to assess if participants that meet the criteria for a TES diagnosis have a specific tau deposition profile on PET scanning using the PET tau binding ligand - [18F] PI-2620.
- Conditions
- Chronic Traumatic Encephalopathy, Traumatic Encephalopathy, Head Injury Trauma, Cognitive Impairment
- Trial name
- TACIT (NCT05490576)
- Testing
- [18F] PI-2620 Tau Ligand
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- Macquarie University, Australia
Acute Kidney Injury, Chronic Kidney Diseases
Impact on Mortality of Screening for Kidney Disease Associated With a Specialized Intervention During Hospitalization in a Territorial Hospital Trust
Kidney disease in its chronic or acute form shares many risk factors for initiation, progression and prognosis with an increase in morbidity and mortality, the length of hospitalization and the cost associated with stages of…
- Trial name
- WARNING KD (NCT05033652)
- Testing
- WARNING KD
- Where
- 3 sites in France
- Volunteers
- 1,179 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
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