Clinical trials: Cigarette Smoking Behavior
Smoking ( Cigarette)
Effect of Buteyko Breathing Exercise Combined With Postural Stability Exercises on Maximal Oxygen Consumption in Young Adult Smokers
Background: Smoking is one of the most significant risk factors for respiratory diseases, affecting both lung function and overall respiratory health.
- Trial name
- BBE PSE VO2max (NCT07257783)
- Testing
- Buteyko breathing exercise combined with postural stability exercises
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Yasmeen Alaa Abd El-Hamied Ahmeed
Smoking
Research Study on the Effects of Smoking on Arteries
The current proposal, will elucidate the role of oxidant stress (OS) on arterial function as measured by flow mediated vasodilation.
- Trial name
- NCT00948454
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
E-Cig Use, Adolescent Behavior
Identifying Student Opinion Leaders to Lead E-cigarette Interventions
This research will explore the feasibility of leveraging social network analysis to identify 6th grade opinion leaders to lead a school-based e-cigarette intervention.
- Trial name
- NCT04083469
- Testing
- Peer-Led Peer-Elected Intervention, Adult-Led Intervention, Peer-Led Non-Elected Intervention
- Where
- United States
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nicotine Dependence
Concurrent Bupropion / Varenicline for Smoking Cessation
This study focuses on the first step in developing an algorithm for maximizing quit-smoking success based on an adaptive approach, which changes treatment from the initial nicotine replacement therapy (NRT) when that treatment…
- Trial name
- ConNic4 (NCT01303861)
- Testing
- Varenicline, Bupropion, Nicotine patches
- Where
- 4 sites in United States
- Volunteers
- 702 people
- Sponsor
- Duke University
Tobacco Use, Tobacco Smoking
Persistence Targeted Smoking Cessation in Serious Mental Illness (SMI)
Due to the pandemic, this study was modified from a randomized clinical trial to test the feasibility, initial efficacy, and mechanisms of action of our PTSC-S intervention to a feasibility and acceptability test of our…
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Tobacco Use Disorder
- Trial name
- PTSC-S (NCT03873337)
- Testing
- Persistence Targeted Smoking Cessation in SMI (PTSC-S), Nicotine patch
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Rutgers, The State University of New Jersey
Nicotine, Vaping
Reduced HPHC Exposure in Cigarette Smokers Switching to P4M3 Gen. 2.0 Compared to Continuing Smoking, or Smoking Abstinence
To demonstrate the reduction of Biomarkers of Exposure (BoExp) to selected harmful and potentially harmful constituents (HPHC) in smokers switching from cigarette (CIG) to P4M3, an Electronic Nicotine Delivery System (ENDS)…
- Conditions
- Nicotine, Vaping, Nicotine Vaping
- Trial name
- NCT05487456
- Testing
- P4M3 CA35, P4M3 CM35, CIG
- Where
- United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Tobacco Smoking, Healthy Participants
Investigation of the Impact of Smoking Status on Allergen-induced Nasal Airway Inflammation Using a Cat Hair (Felis Domesticus) Extract Nasal Allergen Challenge Model
The purpose of this pilot study is to evaluate allergen-induced nasal airway inflammation following nasal application of felis domesticus, or cat, extract in e-cigarette users, cigarette smokers, and non-smokers.
- Conditions
- Tobacco Smoking, Healthy Participants, E-cigarette Smokers
- Trial name
- Kitty Nose (NCT03031145)
- Testing
- Felis Domesticus
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Smoking, Cigarette, Smoking Cessation
Pictorial Warning Labels, Numeracy, and Memory for Numeric Cigarette Health-risk Information Over Time
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks, or for numeric risks (e.g., percentage risk for…
- Trial name
- NCT03501472
- Testing
- text-only PWL, low-emot PWL, high-emot PWL
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Lung Function Testing, Cigarette Smoking
Evaluation of Ventilation Homogeneity as a Marker of Small Airway Disease in Active Smokers
Ventilation heterogeneity is a hallmark feature of most obstructive pulmonary diseases. In particular, chronic obstructive pulmonary disease (COPD) is pathologically and physiologically characterized by small airway destruction…
- Conditions
- Lung Function Testing, Cigarette Smoking, Single-photon Emission Computed Tomography (SPECT), Ventilation Homogeneity
- Trial name
- NCT03728712
- Testing
- SPECT/CT
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Tobacco Smoking, Psychiatric Disorders
The Effect of Electronic Cigarette Use on Smoking Behaviors Among Smokers Receiving Outpatient Psychiatric Treatment
This study aims to establish the feasibility and acceptability of a project designed to investigate the impact of electronic cigarette use on combustible cigarette smoking and smoking-related factors among smokers with…
- Trial name
- NCT04014322
- Testing
- E-cigarette
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Fordham University
Smoking Cessation
Effectiveness of Different THR Products in Adult Population
The study is a two-arm, parallel randomized controlled trial (RCT) with a treatment period of 12 weeks, and long-term follow-up at 52 weeks which plans to enroll 258 smokers from general adult population.
- Trial name
- NCT05825924
- Testing
- E-Cigarette, Nicotine patch
- Where
- Pakistan
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Foundation for a Smoke Free World INC
Diabete Type 2, E Cigarette Use
Switching to E-Cigarettes After Type 2 Diabetes Diagnosis and Health Outcomes
Individuals with T2DM who smoke have higher risks of cardiovascular disease and other complications. Many people consider e-cigarette as a "harm-reduction" alternatives to combustible cigarettes, but it is not clear whether…
- Conditions
- Diabete Type 2, E Cigarette Use, Clinical Outcomes
- Trial name
- E-cig-DM (NCT07414355)
- Testing
- Change in smoking behavior after type 2 diabetes diagnosis
- Where
- South Korea
- Volunteers
- 133,320 people
- Sponsor
- Samsung Medical Center
Cigarette Smoking, E-Cigarette Use
Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette Use
The purpose of this research study is to understand whether concurrent treatment for cigarettes and e-cigarettes in which an individual quits both products at the same time (QUIT-C) or sequential treatment in which an individual…
- Conditions
- Cigarette Smoking, E-Cigarette Use, Smoking Cessation
- Trial name
- NCT06027840
- Testing
- Varenicline, Counseling, Guided Self-Change Booklets
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Yale University
Psychosis, Substance Use
Families With Substance Use and Psychosis: A Pilot Study
The purpose of this study is to develop and evaluate an intervention that adapts Community Reinforcement and Family Training (CRAFT) for families experiencing first episode psychosis and substance use delivered via telemedicine…
- Conditions
- Psychosis, Substance Use, Substance Use Disorders, Family
- Trial name
- NCT04284813
- Testing
- CRAFT-FT
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Smoking, Cigarette Smoking
MapMySmoke: Smoking Cessation App With Geospatial Capture
Place-based cues can be an important trigger of smoking behavior, therefore the investigators wish to learn more about the influence of the built environment on individual smoking behavior.
- Conditions
- Smoking, Cigarette Smoking, Smoking, Tobacco
- Trial name
- NCT02932917
- Testing
- MapMySmoke
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of St Andrews
Smoking Behaviors, Smoking, Cigarette
AAT + tDCS to Reduce Cue-induced Craving and Smoking Behavior
Smokers are highly reactive to smoking-related stimuli and report that this cue reactivity (CR) is a major obstacle to quitting.
- Trial name
- NCT05426460
- Testing
- Approach/Avoidance Task, Transcranial Direct Current Stimulation, AC
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Cynthia Conklin
Cigarette Smoking Behavior, E-Cigarette Use
Project E-Shift: A Harm Reduction Intervention for Chronically Unhoused Smokers.
This pilot randomized trial tested whether switching to e-cigarettes, compared with standard nicotine replacement therapy (NRT; patch and gum), helped adults with a history of chronic homelessness stop smoking combustible…
- Trial name
- ESHIFT (NCT07897058)
- Testing
- E-cigarette, Nicotine replacement therapy (patch, gum), both arms, CO-contingent financial incentives, both arms
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Thomas Jefferson University
Cigarette Smoking, Home Access to Internet and Email
Web-based Smoking Cessation Intervention: Transition From Inpatient to Outpatient
This project, "Web-based Smoking Cessation Intervention: transition from inpatient to outpatient," addresses smoking among hospitalized patients, whose rates are higher than among the general population.
- Conditions
- Cigarette Smoking, Home Access to Internet and Email, Cognitively and Physically Able to Participate, English Speaking and Reading
- Trial name
- NCT01277250
- Testing
- Web-based smoking cessation program
- Where
- United States
- Volunteers
- 1,548 people
- Sponsor
- University of Alabama at Birmingham
Smoking
CSD170302: Study to Assess Nicotine Uptake in Smokers From Electronic Cigarettes
To determine the rate and amount of nicotine uptake with 10-minute ad libitum use of four different marketed electronic cigarettes.
- Trial name
- NCT03233997
- Testing
- FT21018, FT21033, FT21034
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH
This study will examine the short-term cardiovascular (CV) effects of e-liquid pH in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-2 (NCT04449510)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco