Clinical trials: Cigarette Smoking-Related Carcinoma
Cigarette Smoking-Related Carcinoma
Impact of E-cigarette Use on the Body
This study examines how electronic (e)-cigarette use impacts the body, by studying both users and non-users of e-cigarettes. Early evidence indicates that e-cig users experience adverse health effects.
- Trial name
- NCT04972513
- Testing
- Biospecimen Collection, Nitric Oxide Breath Test, Oscillometry
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Text Message and Mail Delivery of Tailored Educational Materials to Improve Access to Resources for Smoking Cessation of Menthol Tobacco Cigarettes
This clinical trial compares the impact of receiving educational materials containing relevant content about risks from smoking menthol cigarettes which include links to the New York (NY) Smoke-Free website by text message or…
- Trial name
- NCT07857681
- Testing
- Educational Intervention, Internet-Based Intervention, Smartphone Application-based Intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial
This phase IV trial investigates how to personalize treatments (such as medications and/or counseling) for quitting smoking based on the unique character traits of participants.
- Trial name
- NCT04604509
- Testing
- Bupropion Hydrochloride Controlled-release, Nicotine Replacement, Questionnaire Administration
- Where
- United States
- Volunteers
- 2,010 people
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma
Studying Flavors and Cooling Agents in Oral Nicotine Pouches to Understand User Preferences
This clinical trial studies how the flavors and synthetic coolant properties in oral nicotine pouches (ONPs) compare to one another and how these characteristics are perceived by users.
- Trial name
- NCT07111234
- Testing
- Carbon Monoxide Measurement, Nicotine Oral Pouch, Questionnaire Administration
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study
This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract…
- Trial name
- NCT05455086
- Testing
- Cigarette Smoking, Computed Tomography, Positron Emission Tomography
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma, E-Cig Use
Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use Cigarettes, E-cigarettes and Cannabis (Co-Tox Study)
This study evaluates the amount of nicotine, cannabis, and toxicants linked to the use of nicotine e-cigarette and/or cannabis products in the blood and urine of young adult users as well as the cannabis and nicotine use…
- Trial name
- NCT07167225
- Testing
- Effectiveness of different recruitment approaches, Choice of study completion locations, Cannabis Engagement Assessment
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults
This trial assesses the acceptability and preliminary efficacy of Empowered, Queer, Quitting, and Living (EQQUAL) smoking-cessation intervention for sexual and gender minority young adult smokers.
- Trial name
- NCT05847673
- Testing
- Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma, Lung Carcinoma
Culturally Tailored Educational Video to Promote Lung Cancer Screening in Vulnerable Communities
This clinical trial evaluates the impact of a culturally tailored educational video on the perceptions of lung cancer and lung cancer screening in vulnerable communities. Lung cancer is the most common cancer type.
- Trial name
- NCT06010355
- Testing
- Discussion, Media Intervention, Interview
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Thomas Jefferson University
Cigarette Smoking-Related Carcinoma
Evaluating the Impact of Quitting Using Executive Function Strategy Training (QUEST) on Smoking Cessation in Homeless Young Adult Smokers
This clinical trial evaluates the impact of Quitting Using Executive Function Strategy Training (QUEST) on quitting smoking (cessation) in homeless young adult smokers with an acquired brain injury (ABI).
- Trial name
- NCT06745154
- Testing
- Biospecimen Collection, Cognitive Assessment, Interview
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers
This randomized early phase I trial studies how well broccoli sprout/broccoli seed extract supplement works in decreasing toxicity in heavy smokers.
- Trial name
- NCT03402230
- Testing
- Broccoli Sprout/Broccoli Seed Extract Supplement, Laboratory Biomarker Analysis, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoking-Related Carcinoma
Evaluating Shared Decision-Making for Lung Cancer Screening Among Chinese Populations in the United States
This study better understands the views on shared decision-making among Chinese adults who smoke or who have a spouse who smokes.
- Trial name
- NCT05024955
- Testing
- Discussion, Interview
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma
Evaluating the Impact of Synthetic Cooling Agents in Combustible Cigarettes on Smoking Perceptions and Use
This clinical trial evaluates the impact of synthetic cooling agents in combustible cigarettes on smoking perceptions and use. Menthol, a natural chemical, is a cooling agent that increases nicotine dependence among smokers.
- Trial name
- NCT06230159
- Testing
- Non-menthol Cigarette Smoking, Menthol Cigarette Smoking, Synthetic Cooling Agent Cigarette Smoking
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Increasing Access to Smoking Cessation and Smoke Free Home Services for Low-Income Pregnant Women in Northeast Texas
This trial seeks to increase access to smoking cessation services to low-income pregnant women. Smoking is associated with an increased risk of developing cancer.
- Trial name
- NCT05051345
- Testing
- Informational Intervention, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
Very Low Nicotine Content Cigarettes and E-Cigarettes in Promoting Smoking Cessation in Daily and Intermittent Cigarette Smokers
This trial studies what would happen if the nicotine levels in cigarettes are greatly reduced, but electronic cigarettes containing different amount of nicotine are available.
- Trial name
- NCT02964182
- Testing
- Cigarette, Nicotine Replacement, Questionnaire Administration
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma
Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes
This early phase I trial studies potential differences between men and women when switching from the use of combustible cigarettes to the National Institute on Drug Abuse's Standard Research E-Cigarette (SREC).
- Trial name
- NCT03856515
- Testing
- Nicotine Replacement, Questionnaire Administration, Electronic Cigarette
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cigarette Smoking-Related Carcinoma
PK/PD of Vaping THC-containing Liquids vs. Smoked Cannabis
We will conduct a randomized, within-subjects clinical study to compare short-term pharmacokinetic (PK) and pharmacodynamic (PD) effects of Δ9-tetrahydrocannabinol (THC) vaping liquids vs.
- Trial name
- NCT06055231
- Testing
- Vape device, Joint, Marijuana via vape device
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers
This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers.
- Trial name
- NCT05121051
- Testing
- Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoking-Related Carcinoma, Tobacco-Related Carcinoma
SmartQuit Program for Smoking Cessation
This trial investigates how well a smartphone-based smoking cessation program called SmartQuit works to help patients stop smoking.
- Trial name
- NCT04510077
- Testing
- SmartQuit Smoking and Tobacco Cessation Program, Survey Administration
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance
This study evaluates histories among cannabis and tobacco co-users of their initiation, escalation, and maintenance of the co-use behavior.
- Trial name
- NCT07439471
- Testing
- Non-Interventional Study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia
This clinical trial compares the use of oral nicotine pouches to nicotine replacement therapy, consisting of nicotine patches and lozenges, to reduce cigarette use in smokers living in rural Appalachia.
- Trial name
- ARISE (NCT06763536)
- Testing
- Carbon Monoxide Measurement, Nicotine Lozenge, Oral Nicotine Pouch
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center