Clinical trials: Cigarette Use
Smoking Cessation, Smoking, Cigarette
Pictorial Warning Labels and Memory for Cigarette Health-risk Information Over Time
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks.
- Trial name
- NCT03375840
- Testing
- Text-only PWL, Low-emot PWL, High-emot PWL
- Volunteers
- 4,424 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Tobacco Use Disorder
Efficacy of Oral Tobacco Products Compared to a Medicinal Nicotine
For the primary goals, we hypothesize that 1) the oral tobacco product will be more efficacious than the medicinal nicotine product in substituting for smoking cigarettes; 2) among non-abstainers, the oral tobacco product will…
- Trial name
- NCT00710034
- Testing
- Oral tobacco, Nicotine Gum
- Where
- 2 sites in United States
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking Cessation, Smoking, Cigarette
Incorporating Financial Incentives to Increase Smoking Cessation Among Asian Americans Residing in New York City
Financial incentives for motivating health change have been increasingly employed in various healthcare sectors. They can be a potentially effective approach to promote smoking behavioral change and increase the use of…
- Trial name
- NCT03397511
- Testing
- Financial Incentives
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Smoking Cessation, Smoking, Cigarette
Grip&Health: Behavioural Intervention to Reduce Smoking, Stress and Improve Financial Health in Low-SES in Rotterdam
Grip\&Health: randomised trial which will examine the effect of theory-based multicomponent behavioural intervention for reducing stress, smoking and improving financial health and perceived health of low-SES residents in…
- Conditions
- Smoking Cessation, Smoking, Cigarette, Smoking, Stress
- Trial name
- Grip&Health (NCT03553979)
- Testing
- Stress management program (SM), Stress management + Buddy program (SM-B)
- Where
- Netherlands
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Nicotine Dependence
Coping Skills Treatment for Smoking Cessation
The primary purpose of this study is to evaluate the efficacy of a new type of exposure- and acceptance-based smoking cessation treatment vs.
- Trial name
- Project-WIN (NCT01061528)
- Testing
- Transdermal Nicotine
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Electronic Cigarette
Nicotine Pharmacokinetic in Blood and Analysis of Exhaled Breath After E-cigarette Smoking.
Electronic or e-cigarettes are battery-powered devices that deliver vapor which may be inhaled in the manner tobacco is smoked. The e-liquid is usually a solution containing propylene glycol and/or vegetable glycerin, nicotine…
- Trial name
- VAPexp'Air (NCT03573154)
- Testing
- administration of the liquid 1 and then the liquid 2, administration of the liquid 2 and then the liquid 1
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Smoking, Cigarette Smoking
Effect of Helpers Program On-line Training on Smoking Relapse and Social Networks
The purpose of this study is to assess the effect of the Helpers Stay Quit training on abstinence over time of newly abstinent smokers, and on the interactions they have with their personal network related to smoking and smoking…
- Trial name
- NCT05641974
- Testing
- Helpers Stay Quit Training
- Where
- United States
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Periodontitis (Stage 3), Periodontal Health
Evaluation of the Effect of Smoking on Apelin, Periostin, and High-Sensitivity CRP Levels in Gingival Crevicular Fluid and Serum
Periodontal health is influenced by various local and systemic factors, with smoking being one of the major environmental risk factors.
- Conditions
- Periodontitis (Stage 3), Periodontal Health, Smoking Cigarette
- Trial name
- NCT07870473
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Tobacco Use
Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes
This study is designed to evaluate the abuse liability of very low nicotine cigarettes compared to nicotine gum and usual brand cigarettes
- Trial name
- NCT03559751
- Testing
- VLN cigarettes (A), Usual Brand Cigarettes (B), Nicotine gum (C)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- 22nd Century Group, Inc.
Electronic Cigarette Use
Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC
The goal of this study is to conduct a pilot randomized waitlist-controlled trial to assess the feasibility, acceptability, and preliminary effects of substituting the NIDA standardized research e-cigarette (SREC) for combusted…
- Trial name
- SWITCHED (NCT05881304)
- Testing
- Standardized research e-cigarette (SREC)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cigarette Smoking, Tobacco Use
Electronic Cigarette Use in Young Adult Men and Women
This one-year pilot study of 30 non-treatment seeking young adult e-cigarette/combustible tobacco product dual users (15 males/15 females) will use smartphone-based ecological momentary assessment (EMA) to gather real-time data…
- Trial name
- NCT03089541
- Testing
- Survey Arm
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking
Impact of Exclusive Use of Low Nicotine Cigarettes on Compensatory Smoking
Smoking is the leading cause of preventable death in the United States. An FDA-mandated reduction in the nicotine content of cigarettes might reduce the health burden of tobacco by reducing the prevalence of smoking.
- Trial name
- NCT03311646
- Testing
- Normal nicotine content cigarettes (NNC, Baseline), Very low nicotine content (VLNC)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Abuse Tobacco, Exposure
Perceptions of E-Cigarettes and Synthetic Cooling Agents, The ICE Study
This study evaluates how synthetic cooling additives like WS-3 and WS-23 impact e-cigarette perceptions, use behavior, and toxicant exposure.
- Trial name
- ICE (NCT06208202)
- Testing
- Behavioral Intervention, Biospecimen Collection, Survey Administration
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Tobacco Use, Tobacco Smoking
Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco
The current study aimed to test a culturally tailored program designed to help Pacific Islanders (PIs) between the ages of 18 and 30 quit smoking cigarettes by using a randomized controlled trial design with one intervention…
- Conditions
- Tobacco Use, Tobacco Smoking, Tobacco Use Cessation, Smoking
- Trial name
- MPACT (NCT03238456)
- Testing
- Motivating Pacifika Against Cigarettes and Tobacco
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Claremont Graduate University
Smoking, Tobacco Smoking
Reduced Exposure to HPHC in Smokers Switching From Cigarettes to Different Versions of THS
This was a randomized, controlled, open-label, 4 parallel arm study with a stratified randomization by sex (a quota for each sex [females and males] of at least 40% overall).
- Conditions
- Smoking, Tobacco Smoking, Tobacco Use
- Trial name
- NCT05599451
- Testing
- THS Blade device, THS Induction Mono device, THS Induction Mid device
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Smoking, Smoking, Cigarette
Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2
The purpose of the study is to evaluate how limiting the nicotine content in regular cigarettes affects choices for regular cigarette and e-cigarette products.
- Conditions
- Smoking, Smoking, Cigarette, E-Cig Use, Nicotine Dependence
- Trial name
- NCT05473585
- Testing
- very low nicotine content cigarettes, normal nicotine content cigarettes, Study e-cigarette
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Product Beliefs and Use
Effects of FDA Authorized Smokeless Tobacco Claims Among US Adults Who Smoke Cigarettes
This study will be an online survey experiment conducted with adults who smoke cigarettes (ages 21+) to examine their reactions to modified risk advertising claims authorized by the Food \& Drug Administration (FDA) for two…
- Trial name
- NCT06927700
- Testing
- Modified Risk Claim Type - None, Product Brand - General Snus, Product Brand - Copenhagen
- Where
- United States
- Volunteers
- 1,257 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Smoking, Tobacco Use
Salt-Based E-cigarette
Electronic nicotine delivery systems (ENDS) vary on a wide range of characteristics, which may impact the reinforcement value of the products compared to more harmful combustible products.
- Trial name
- NCT04238832
- Testing
- Salt Base Nicotine, Free Base Nicotine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Nicotine Dependence
Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers
The goal is to examine sex differences in amphetamine-induced dopamine release in tobacco smokers and nonsmokers.
- Trial name
- NCT02348385
- Testing
- Amphetamine
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yale University
Cigarette Smoking, Addiction
Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population.
- Conditions
- Cigarette Smoking, Addiction, E Cig Use
- Trial name
- NCT04063267
- Testing
- E cigarettes, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health