Clinical trials: Circumcision
Breastfeeding, Exclusive, Circumcision
Circumcision and Breastfeeding
1) To determine when the majority of male infants are being circumcised at 3 hospitals across the US (Brooke Army Medical Center, Naval Medical Center San Diego, and Dartmouth Hitchcock Medical Center.
- Trial name
- NCT03619369
- Testing
- Circumcision
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Analgesia
Combination Analgesia for Neonatal Circumcision
Circumcision is a commonly performed procedure on newborn males. Clear recommendations and/or guidelines for pain control during the procedure do not exist.
- Trial name
- NCT02990364
- Testing
- Sucrose, Lidocaine, EMLA Topical Product
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Phimosis, Paraphimosis
Evaluating the Efficacy of 2-Octyl Cyanoacrylate (2-OCA) With Four Interrupted Sutures in Adult Male Circumcision
This study aims to determine whether cyanoacrylate glue is a non-inferior alternative to continuous suturing for wound closure following adult circumcision.
- Trial name
- NCT06487494
- Testing
- Circumcision wound closure using 2-octyl cyanoacrylate glue with four interrupted sutures, Circumcision wound closure using continuous sutuing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
HIV Infections, Acquired Immunodeficiency Syndrome
Text Messaging to Improve Adherence to Clinic Visits and Reduce Early Resumption of Sexual Intercourse After Male Circumcision
Male circumcision (MC) reduces, by more than half, the risk of HIV-1 acquisition. WHO and UNAIDS recommend that "male circumcision should be recognized as an efficacious intervention for HIV prevention especially in countries and…
- Conditions
- HIV Infections, Acquired Immunodeficiency Syndrome, Circumcision, Male, Patient Compliance
- Trial name
- NCT01186575
- Testing
- Text Message
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Washington
Circumcision
Evaluation of the ShangRing vs. Mogen Clamp for Early Infant Male Circumcision (EIMC) in Sub-Saharan Africa
The study will evaluate the safety and acceptability of the topical anesthesia-based, no-flip ShangRing technique vs. Mogen clamp for Early Infant Male Circumcision (EIMC) in neonates and infants up to 60 days of life.
- Trial name
- NCT03338699
- Testing
- ShangRing, Mogen clamp
- Where
- 3 sites in Kenya, Tanzania and 1 more
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Male Circumcision
The Effect of Two Different Interventions Applied During the Transfer of Children to the Operating Room for Circumcision on Fear, Anxiety, Comfort and Pain Levels
The aim of this randomized controlled experimental study was to determine the effects of two different interventions on fear, anxiety, comfort, and pain levels during the transfer of children undergoing circumcision to the…
- Trial name
- NCT07094555
- Testing
- Animal Assisted Practice, Kaleidoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- MELİS CAN KESGİN GÜNGÖR
Newborn; Infection, Disinfection
Preoperative Antiseptic in Newborn Circumcision Comparison of Povidone Iodine and Hypochlorous Acid Used
Comparison of Povidone iodine and Hypochlorous acid used as a Preoperative Antiseptic in Newborn Circumcision abstract Aim: Circumcision is one of the most common surgical procedures in all age groups.
- Conditions
- Newborn; Infection, Disinfection, Circumcision
- Trial name
- NCT05175027
- Testing
- hypochlorous acid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Pain, Postoperative, Phimosis
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT04646967
- Testing
- Bupivacain, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
HIV Infections, Circumcision
Infant Male Circumcision in Gaborone, Botswana, and Surrounding Areas: Feasibility, Safety and Acceptability
Background: Novel HIV prevention approaches are urgently needed in Botswana and elsewhere in sub-Saharan Africa. Although adult male circumcision (MC) has been shown to reduce the heterosexual acquisition of HIV by men by about…
- Trial name
- NCT00971958
- Testing
- Circumcision, Mogen Clamp, Plastibell
- Where
- Botswana
- Volunteers
- 1,235 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Male Circumcision
Phase 4 Field Trial of the Unicirc Instrument With Tissue Adhesive
This is a field trial of the Unicirc instrument to excise the foreskin, plus use of cyanoacrylate tissue adhesive to seal the wound.
- Trial name
- Unicirc003 (NCT02091726)
- Testing
- Unicirc instrument plus cyanoacrylate tissue adhesive
- Where
- South Africa
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
Penile Infection, Penile Haematoma
Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania
The goal of this observational study was to evaluate the safety and acceptability of the ShangRing device for male circumcision among men in Shinyanga, Tanzania.
- Conditions
- Penile Infection, Penile Haematoma, Penile Bleeding, Deformity
- Trial name
- NCT06273696
- Testing
- ShangRing
- Where
- 2 sites in Tanzania
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- IntraHealth International
Medical Male Circumcision
An Implementation Science Study Investigating Profiles of Men Interested in MMC
There are both supply and demand gaps in our understanding of how best to implement MMC services. In terms of supply of MMC services, there is a need to better understand what the best way is of efficiently accessing mature…
- Trial name
- Imbizo (NCT02352961)
- Testing
- Exclusive Intervention Strategy
- Where
- South Africa
- Volunteers
- 2,817 people, healthy volunteers welcome
- Sponsor
- The Aurum Institute NPC
Circumcision
Effects of Therapeutic Touch and Music on Children's Anxiety, Pain, and Nausea Before and After Circumcision
This randomized controlled trial aims to evaluate the effects of therapeutic touch and music therapy on anxiety, pain, and nausea in children undergoing circumcision surgery.
- Trial name
- NCT07728266
- Testing
- Therapeutic Touch, Music intervention
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Igdir University
Circumcision
A Randomized Controlled Trial of Open Surgical vs. Rapid, Minimally-invasive Voluntary Adult Male Circumcision
To identify a minimally-invasive surgical circumcision technique for men, which is easy to learn and perform, is safe, and is associated with high patient satisfaction and excellent cosmetic results.
- Trial name
- NCT01877408
- Testing
- Open surgical circumcision, Unicirc device with tissue adhesive
- Where
- South Africa
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
HIV
Male Circumcision Against HIV Hukomboa
Tanzania launched a National Strategy for scaling-up voluntary medical male circumcision in 2010, and aims to circumcise 2.8 million males by 2015.
- Trial name
- NCT02376348
- Testing
- A targeted demand creation Activities
- Where
- 2 sites in Tanzania
- Volunteers
- 10,782 people, healthy volunteers welcome
- Sponsor
- National Institute for Medical Research, Tanzania
Voluntary Medical Male Circumcision
Two-way Texting for VMMC Follow-up in Republic of South Africa
Voluntary medical male circumcision (alternatively abbreviated in the literature as VMMC or MC) is a critical HIV prevention intervention with global support for expansion across sub-Saharan Africa (SSA).
- Trial name
- 2wT_RSA (NCT04327271)
- Testing
- Text-based VMMC follow-up
- Where
- 9 sites in South Africa
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- University of Washington
Circumcision, Male
Unicirc Adolescent 12-15 Year Old Boys
This is a field case series of Unicirc under topical anaesthetic among adolescent boys, aged 12 to 15 years.
- Trial name
- NCT02593630
- Testing
- Unicirc circumcision
- Where
- South Africa
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
Bleeding, Site Infection
Outcome of Plastibell Circumcision Versus Open Method Circumcision
To compare the outcomes of plastibell circumcision method with open surgical technique in infants presenting at tertiary care hospital.
- Trial name
- NCT06366984
- Testing
- plastibell, open method
- Where
- Pakistan
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Male Circumcision
Safety Study of the PrePex Device for Non-Surgical Adult Male Circumcision During Phased in National Implementation in an Effort to Prevent the Spread of HIV
It is well known from a range of observational and epidemiological studies that the lifetime risk of acquiring HIV among males can be significantly reduced via circumcision.
- Trial name
- RMC-07 (NCT01921608)
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda