Clinical trials: Circumcision
HIV/AIDS
Evaluating Demand Creation Strategies for Voluntary Medical Male Circumcision (VMMC) in Kenya
The purpose of this study is to evaluate the impact of two interventions - Inter-Personal Communication [IPC] and Dedicated Service Outlets [DSOs] - in recruiting men aged 25-39 years for Voluntary Medical Male Circumcision…
- Trial name
- TASCO (NCT02497989)
- Testing
- Inter-personal Communication (IPC), Dedicated Service Outlets (DSO)
- Where
- Kenya
- Volunteers
- 2,785 people, healthy volunteers welcome
- Sponsor
- Impact Research & Development Organization
Pain, Postoperative, Phimosis
An Evaluation of Pain Outcomes of Ketorolac Administration in Children Undergoing Circumcision
Circumcision is the most common surgical procedure performed by Pediatric Urologists. Ketorolac has been shown to have an efficacy similar to morphine in multi-modal analgesic regimens without the commonly associated adverse…
- Conditions
- Pain, Postoperative, Phimosis, Paraphimosis, Balanitis
- Trial name
- NCT04646967
- Testing
- Bupivacain, Sevoflurane, Acetaminophen
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alberta Children's Hospital
Male Circumcision
A Prospective Field Study: Introducing the Shang Ring in Routine Clinical Settings
Male Circumcision (MC) is the only new biomedical method to demonstrate consistent efficacy as an HIV prevention intervention in randomized controlled trials (WHO and UNAIDS, 2007), based on three randomized controlled trials in…
- Trial name
- NCT01567436
- Testing
- Shang Ring
- Where
- 2 sites in Kenya, Zambia
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- FHI 360
Voluntary Medical Male Circumcision
Assessing the Impact of a Digital VMMC Platform
VMMC has been identified as a crucial intervention by UNAIDS to achieve the 2030 global target of a 90% reduction in new HIV infections compared with 2010 levels.
- Trial name
- VMMC NEXUS (NCT06364891)
- Testing
- VMMC NEXUS Digital application
- Where
- Zambia
- Volunteers
- 150,383 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Fear, Anxiety
Immersive Virtual Reality and Music During Circumcision in Children
The goal of this randomized controlled trial is to examine the effectiveness of immersive virtual reality (IVR) and music on children's anxiety, fear, and pain levels during circumcision surgery.
- Conditions
- Fear, Anxiety, Child
- Trial name
- NCT06255548
- Testing
- Immersive virtual reality group, Music group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Pain, Circumcision
Acetaminophen and Post Circumcision Pain Control
Infants do not routinely receive acetaminophen for pain control after circumcision. This study will determine if acetaminophen is effective at controlling infant pain after circumcision using nerve block and oral dextrose.
- Trial name
- NCT02498483
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Columbia University
Neonatal Male Circumcision
Enhanced Provision of Male Circumcision (MC) for HIV Prevention, Rakai, Uganda
Background: Medical male circumcision (MMC) for HIV prevention is a priority in 14 East and Southern African countries, and the long-term sustainability of MMC programs could best be achieved by early infant male circumcision…
- Trial name
- NCT02596282
- Testing
- Neonatal circumcision under topical anesthesia
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Penile Infection, Penile Haematoma
Evaluation of the Acceptability and Safety of the ShangRing Device for Male Circumcision in Shinyanga, Tanzania
The goal of this observational study was to evaluate the safety and acceptability of the ShangRing device for male circumcision among men in Shinyanga, Tanzania.
- Conditions
- Penile Infection, Penile Haematoma, Penile Bleeding, Deformity
- Trial name
- NCT06273696
- Testing
- ShangRing
- Where
- 2 sites in Tanzania
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- IntraHealth International
Circumcision, Male, Circumcision Status: Circumcised, Uncircumcised
Increasing Medical Male Circumcision Uptake
The main objective of this study is to reach 80% circumcised men in a random sample of men living in the township of Orange Farm (South Africa).
- Trial name
- NCT02511548
- Testing
- Financial incentive
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Progressus
Medical Device Complication
Feasibility Study of PrePex Device When Performed on Early Infants & Children Male Population by Physicians
The PrePex is a WHO prequalified medical device for adult male circumcision for HIV prevention. The Government of Rwanda was the first country to implement the PrePex and acts as the leading Center of Excellence providing…
- Trial name
- RMC-06 (NCT02281461)
- Testing
- Male circumcision using a non-surgical device
- Where
- Rwanda
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Circumcision
Rapid, Minimally-invasive Voluntary Adult Male Circumcision
This study will evaluate a new, minimally-invasive surgical circumcision technique for men, which is easy to learn and perform, is safe, and is associated with high patient satisfaction and excellent cosmetic results.
- Trial name
- NCT01998360
- Testing
- Surgical Control, Unicirc with tissue adhesive
- Where
- South Africa
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Simunye Primary Health Care
Male Circumcision
Male Circumcision (MC) Using the ShangRing™ Device in Malawi
This prospective study will evaluate the safety and acceptability of the ShangRing device for medical male circumcision (MMC) during routine service delivery in Namitete, Malawi
- Trial name
- NCT02309710
- Testing
- ShangRing
- Where
- 2 sites in Malawi
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- FHI 360