Clinical trials: Citrate
Anosmic and Hyposmic Patients
A Study of the Effects of Sodium Citrate on Olfactory Thresholds
The study will be undertaken at the ENT department of the Leicester Royal Infirmary and in a research laboratory at the University of Leicester and also in the ENT department at the West Suffolk Hospital.
- Trial name
- NCT00409812
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Fetal Distress, Perinatal Asphyxia
Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The PRISM pilot feasibility study consists of two phases to determine: 1) to delivery practices, rates of primary and secondary outcomes, and feasibility of enrollment rates, and 2) to assess the feasibility and acceptability of…
- Conditions
- Fetal Distress, Perinatal Asphyxia, Birth Asphyxia, Stillbirth
- Trial name
- PRISM (NCT05946681)
- Where
- Zambia
- Volunteers
- 1,017 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Ovarian Stimulation
Clomiphene Citrate (CC)/Gonadotropin/Gonadotropin Releasing Hormone (GnRH) Antagonist Versus Gonadotropin/GnRH Agonist
Objective: To compare the efficacy of using mild ovarian stimulation protocol and conventional stimulation protocol in IVF outcome. Design: Prospective randomized trial Setting: University IVF setting.
- Trial name
- NCT00830492
- Testing
- clomiphene citrate, Ultrasound, GnRH antagonist
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Healthy
A Bioequivalence Study of Sildenafil Citrate Orally-Disintegrating Film Dosage Form
The purpose of this study is to assess the bioequivalence of Sildenafil ODF 50 mg to Viagra® tablet 50 mg under fasted conditions.
- Trial name
- NCT04391868
- Testing
- Viagra Tablet, Sildenafil Citrate ODF
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Bone Density
Bone Density in Voluntary Apheresis Blood Donors
A longitudinal, randomized, controlled, single-center Phase IV clinical trial will be performed to assess changes in bone mineral density (BMD) among voluntary apheresis blood donors.
- Trial name
- ALTRUYST (NCT02655055)
- Testing
- high frequency voluntary apheresis blood donation
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Versiti Blood Health
Healthy
Zinc Absorption From Zinc Citrate, Zinc Gluconate and Zinc Oxide
The goal of this trial is to evaluate zinc citrate, a zinc compound with promising sensory properties and a high zinc content, as an alternative zinc compound to be used for supplementation or food fortification.
- Trial name
- NCT01576627
- Testing
- zinc citrate, Zinc Gluconate, Zinc oxide
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Bowel Preparation
Different Dosing Time of Bowklean for the Bowel Preparation
The primary objective of this study is to compare the efficacy of administration routine bowel cleansing medication (Bowklean) for the Bowel Preparation at Different Times Prior Colonoscopy in the morning or in the afternoon.
- Trial name
- NCT04483037
- Testing
- Bowklean
- Where
- Taiwan
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Cystic Fibrosis
A New Optical Sweat Test Method Based on a Citric Acid-derived Multi-halide Sensor
Cystic Fibrosis (CF) is a hereditary multi-system disease affecting approximately 30,000n children and adults in the USA. The diagnosis of CF requires biochemical confirmation (either abnormal sweat chloride measurement and/or…
- Trial name
- NCT03367494
- Testing
- Measurement of Sweat Chloride and Sweat Bromide
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Premature Ejaculation
Combined On-demand Sildenafil Citrate and Tramadol Hydrochloride for Treatment of Premature Ejaculation
Premature Ejaculation (PE) is a common sexual dysfunction that has a negative impact on both sex partners. Several lines of treatment have been proposed for the treatment of PE i.e.
- Trial name
- NCT05183334
- Testing
- Sildenafil 50 mg, Tramadol Hydrochloride 100 MG
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pharmacokinetics of Anatabine
Safety, Tolerability, and Pharmacokinetics of Modified and Immediate Release Anatabine Citrate Formulations
Parts 1 and 2: Subjects take 1 dose of various formulations of the study product, and provide samples for pharmacokinetic (PK) analysis after each, with at least 7 days between doses.
- Trial name
- NCT02432313
- Testing
- Modified Release Formulation x (MRx)
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Healthy Adults
Comparative Pharmacokinetics and Safety of 3 Different Formulations of TNX-102 2.8 mg SL Tablets and Cyclobenzaprine 5 mg Oral Tablet in Healthy Adults
Very low dose (VLD) cyclobenzaprine at bedtime has shown promise as a treatment for fibromyalgia, but the chemistry of cyclobenzaprine requires new formulation technology for bedtime use.
- Trial name
- NCT01889173
- Testing
- TNX-102 SL Tablets at 2.8 mg, TNX-102-B SL Tablets at 2.8 mg, TNX-102-C SL Tablets at 2.8 mg
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tonix Pharmaceuticals, Inc.
Testosterone Deficiency
Pharmacokinetic Evaluation of Serum Testosterone Concentrations After Administration of Clomiphene Citrate
This is a randomized, open-label trial examining two doses of clomiphene citrate in men with low serum testosterone concentrations (total testosterone (TT) < 300 ng/dl).
- Trial name
- NCT05096169
- Testing
- Clomiphene Citrate 25mg, Clomiphene Citrate 50mg
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
PCOS
N-Acetylcysteine and L-carnitine in Pcos
N-Acetylcysteine and L-carnitine were used in pcos patients
- Trial name
- NCT03164421
- Testing
- N-Acetylcysteine, L-carnitine
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Biological Availability
Pharmacokinetics of Fentanyl Following Intravenous and Oral Routes of Administration in Healthy Volunteers
The purpose of the study is to compare the pharmacokinetics of fentanyl following i.v. and oral administration in healthy volunteers, and to assess the bioavailability of fentanyl following oral administration.
- Trial name
- NCT00714558
- Testing
- Fentanyl citrate; Naltrexone; Naloxone
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Catheter Blockage
UROtainer for Bladder Catheter Maintenance, Infection Prevention and Quality of Life
The purpose of the current study is to investigate whether catheter flushing with Uro-Tainer® with citric acid and Uro-Tainer® Polihexanide can: Reduce catheter changes due to incrustation and blockage.
- Trial name
- UROBIQ (NCT05775614)
- Testing
- UroTainer®, Saline
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
IUGR
Viagra for the Treatment of IUGR
It has been suggested that Viagra (or other drugs that inhibit PDE-5, the enzyme that normally inhibits blood vessels' ability to expand) may have beneficial effects in hypertensive pregnancy and, possibly, preeclampsia.The…
- Trial name
- NCT00347867
- Testing
- Viagra administration in IUGR/PET pregnancies
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Exercise-Induced Fatigue, Athletic Performance
The Effect of Individual Sodium Citrate Consumption on Repeated Sprint Performance in Female Soccer Players
The aim of this research is to determine whether sodium citrate supplementation, taken at the best individual time, would improve repeated sprint performance in professional female soccer players.
- Conditions
- Exercise-Induced Fatigue, Athletic Performance, Soccer
- Trial name
- ITSCORE-F (NCT07737327)
- Testing
- Sodium Citrate Oral Product
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy Subjects
Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution
This is a randomised, open-label, 3-period, crossover single dose study to assess the relative bioavailability of two formulations of HTL0016878: an oral solution of HCl salt form (the reference product) and an oral capsule…
- Trial name
- NCT04935320
- Testing
- HTL0016878.HCl Solution 10 mg, HTL0016878.Citrate Capsule 10 mg
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nxera Pharma UK Limited
Infertility
Cost Effectiveness Analysis for Induction of Ovulation in the Polycystic Ovary Syndrome by Letrozole Versus Clomiphene Citrate
To evaluate cost effectiveness of Letrozole versus clomiphene citrate (CC) in induction of ovulation in patients with polycystic ovary syndrome.
- Trial name
- NCT04361175
- Testing
- Letrozole, Clomiphine Citrate
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Assiut University
Polycystic Ovarian Syndrome
Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case
Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and…
- Trial name
- NCT06813118
- Testing
- Clomiphene Citrate and letrozole
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- HITEC-Institute of Medical Sciences