Clinical trials: Class III Malocclusion
Malocclusion, Angle Class I, Malocclusion, Angle Class II
3D Printed Occlusal Splints for Intraoperative Use
A 3D printed intraoperative occlusal splint is a custom-made biocompatible resin guide that allows surgeons properly align a patient's upper and lower dentition during surgery.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- NCT07079111
- Testing
- Formlabs 3D printed occlusal splint, Industry made occlusal splint
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Class III Malocclusion, Underbite
Effects of Class III Elastics on Stability of Orthopaedic Class III Correction
The purpose of this study is to evaluate the effects of adding elastics to orthodontic retainers on the stability of class III correction and whether it reduces the need for jaw surgery.
- Trial name
- NCT04911400
- Testing
- Upper-lower clear plastic retainers + Class III elastics, Upper-lower clear plastic retainers
- Where
- 2 sites in Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sydney Local Health District
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Class III Malocclusion in Growing Patients
Changes Following the Treatment of Lower Jaw Protrusion Using Two Appliances
An in vivo study evaluating the efficacy of the Tandem appliance in the treatment of maxillary deficiency in growing patients compared to the conventional facemask appliance treatment.
- Trial name
- NCT02144324
- Testing
- Tandem Appliance
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Skeletal Class III Malocclusion
Efficacy of RME and Facemask Therapy for Class III Malocclusion
This multicenter randomized controlled trial compares the efficacy of Rapid Maxillary Expansion (RME) combined with facemask (FM) protraction versus FM protraction alone in treating growing children with skeletal Class III…
- Trial name
- NCT07053683
- Testing
- Combined RME and Facemask Therapy, Facemask Therapy Alone
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Palatal Expansion Technique, Cleft Lip and Palate
MARPE in Patients With Cleft Lip and Palate
The objective of this randomized controlled study will be to evaluate the dental and skeletal effects of maxillary protraction with a facemask, associated with MARPE and Class III elastics in patients with unilateral cleft lip…
- Conditions
- Palatal Expansion Technique, Cleft Lip and Palate, Class III Malocclusion, Skeletal Malocclusion
- Trial name
- NCT04354116
- Testing
- Rapid maxillary expansion, Maxillary Protraction
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Multiple Sclerosis
Motor Evoked Potentials With Modified Facilitation Technique
Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in…
- Trial name
- EP-F (NCT03646929)
- Testing
- MEP using standard facilitation technique, MEP using modified facilitation technique
- Where
- Switzerland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Maxillary Prognathism, Maxillary Retrusion
Custom Made Plate in Orthognathic Surgery
Orthognathic surgery has traditionally been used to correct dentofacial deformities. Conventional methods rely on 2D radiographic images, occlusal splints, and dental casts, but these approaches have limitations, such as errors…
- Trial name
- OGS (NCT06772688)
- Testing
- orthognathic surgery
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Dentofacial Deformities
Correlation Between Dental Inclination and Bone Thickness in Patients With Class III Dentofacial Deformities
The correlation between tooth inclination and bone thickness and the comparison between thickness measurements and buccolingual inclination before and after dental decompensation will be evaluated through tridimensional images in…
- Trial name
- NCT02491619
- Testing
- orthodontic decompensation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Michelle Sendyk
Malocclusion, Angle Class III, Crossbite (Anterior) (Posterior)
Comparison of Two Miniscrew Anchored Maxillary Protraction Protocols
This study evaluates the dentoskeletal effects produced by two maxillary protraction protocols in adolescent patients. Half of participants will be treated with a tooth-borne and tooth-bone-borne expanders as anchorage in the…
- Trial name
- NCT03712007
- Testing
- MAMP therapy with MARPE expander, MAMP therapy with Hyrax expander
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Malocclusion, Angle Class III
Dentofacial Effects Of Two Non-Compliance Appliances In The Treatment Of Growing Skeletal Class III Patients
Early orthodontic treatment of Class III malocclusions with skeletal and dentoalveolar imbalances, represents a continuous dilemma.
- Trial name
- NCT04825951
- Testing
- CS 2000
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malocclusion, Anxiety
Patient Education Before Orthognathic Surgery
To evaluate the effectiveness in the use of an educational material through: Assessment of knowledge about post-operative orthognathic surgery; assessing levels of anxiety with the survey of Anxiety Inventory-STATE-TRAIT…
- Conditions
- Malocclusion, Anxiety, Micrognathism, Prognathism
- Trial name
- NCT01803204
- Testing
- Booklet - Preoperative Educational
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo
Class III Malocclusion, Skeletal Malocclusion
Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol
This study investigated two different methods of maxillary protraction in growing patients with skeletal Class III malocclusion characterized by maxillary deficiency.
- Conditions
- Class III Malocclusion, Skeletal Malocclusion, Maxillary Deficiency
- Trial name
- MiniFM (NCT07279662)
- Testing
- Skeletal Anchorage Supported Maxillary Protraction, Tooth-Borne Maxillary Protraction Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Murat Kaan Erdem
Class III Malocclusion
Treatment of Skeletal Class III Malocclusion Using Orthodontic Removable Traction Appliance
This experimental study aims to evaluate the efficiency of the orthodontic removable traction appliance in the treatment of skeletal class III malocclusion.
- Trial name
- NCT03172442
- Testing
- Vacuum plate, Rapid maxillary expander, Class III elastics
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Class III Malocclusion
3D Printed Reverse Twin Block for Class III Malocclusion
This RCT aims to evaluate the effectiveness of a novel 3D printed reverse twin block appliance in the management of maxillary deficiency in growing patients having class III malocclusion.
- Trial name
- 3DRTB (NCT07710391)
- Testing
- 3D printed Reverse Twin Block appliance, Conventional Reverse Twin Block appliance
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University of Baghdad
Mandibular Prognathism, Orthognathic Surgery
Evaluating the Accuracy of Soft Tissue Prediction in Patients With Mandibular Prognathism After Orthognathic Surgery Using Handheld Scanner Versus Optical Scanner A Prospective Clinical Trial
Aim of study: To evaluate the accuracy of soft tissue prediction in orthognathic surgery using handheld scanners versus optical scanners.
- Trial name
- NCT06724497
- Testing
- face scanning pre and post orthognathic surgery
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Cairo University
Malocclusion, Angle Class III
Periodontal Ligament Stress Level and Tooth Movement
Orthodontic treatment requires application of force systems to individual teeth or groups of teeth, which results in a cellular response with periodontal ligament (PDL) and alveolar bone remodeling.
- Trial name
- NCT00099814
- Testing
- Two different loop designs which deliver distinctive forces
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Skeletal Class III Malocclusion
Surgery-First Orthognathic Surgery in Skeletal Class III Treatment
This study evaluates the efficacy and stability of the "Surgery-First" approach (SF approach) in treating patients with skeletal Class III malocclusion, utilizing a combined retrospective and prospective data collection method.
- Trial name
- NCT07433842
- Testing
- Surgery-First Orthognathic Surgery
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Hanoi Medical University
Class III Malocclusion, Dentofacial Anomalies, Including Malocclusion
Intraoral Device vs Facial Mask for Class III Treatment
The aim of this randomized controlled trail is to compare the efficacy of an intraoral device (the Carriere® Motion 3D™ Class III Appliance) with the facial mask for the early treatemnt of Class III malocclusion.
- Trial name
- NCT04387175
- Testing
- Carriere Motion 3D Class III Appliance, Facial mask
- Volunteers
- 32 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Skeletal Class III Malocclusion
Figuring Out the Genetic Mutations That Lead to Lower Jaw Advancement More Than the Upper Jaw
Purpose of the Research: To reveal the genetic cause for the occurrence of Class III malocclusion, or what may be described as a reverse bite (underbite). Introduction and Detailed Procedures for the Patient (Work Plan): 1.
- Trial name
- NCT07749638
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University