Clinical trials: Clinical
Healthy Volunteers
Phase I Clinical Study of MWN109 Tablets in Healthy Chinese Participants
This is a randomized, double-blind, placebo-controlled, Phase 1 clinical study conducted in China to evaluate the safety, tolerability, pharmacokinetic (PK), and the effect of meal timing following single and multiple oral doses…
- Trial name
- NCT07787611
- Testing
- MWN109 tablet
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Healthy Volunteers
Thorough QT/QTc (TQT) Clinical Study to Evaluate the Effects of Ziresovir on Cardiac Repolarization in Healthy Subjects
This is a single-center, randomized, partially double-blind, placebo and active-controlled, 4-period crossover design thorough QT/QTc (TQT) clinical study to evaluate the effects of ziresovir on cardiac repolarization in healthy…
- Trial name
- NCT06591845
- Testing
- Ziresovir 125 mg, Ziresovir 500 mg, Moxifloxacin hydrochloride tablet 400 mg
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Shanghai Ark Biopharmaceutical Co., Ltd.
Healthy Subjects, Healthy Adult
Development of a Clinical Photographic Atlas for Skin Aging Based on the Characterization of Facial Dermal Collagen Using LC-OCT Technology
This is a single-center, single visit study conducted in healthy female subjects, aged 20 to 75 years inclusive meeting specific inclusion/exclusion criteria.
- Trial name
- NCT07409675
- Testing
- LC-OCT acquisitions on the forehead, Perform standardized photographs using ColorFace, LC-OCT acquisitions on forehead
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Vichy Laboratoires
Breast Cancer
Clinical Trial of Quantitative Detection Kit for Hsp90α in Breast Cancer
Detect plasma Hsp90α concentration of breast cancer patients, healthy volunteers, benign breast diseases patients
- Trial name
- NCT02324101
- Testing
- Hsp90
- Where
- China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Beijing Protgen Biotechnology Development Co., Ltd.
Ovarian Cancer, Healthy Volunteers
Safety and Biodistribution of Technetium Tc 99m EC20 in Normal Volunteers and Ovarian Cancer Patients
Open-label, single-center, single-treatment group, baseline-controlled (for safety) study of the safety and biodistribution of Technetium Tc 99m EC20 in four normal subjects and four subjects with known or suspected ovarian…
- Trial name
- NCT01689636
- Testing
- Tc 99m EC20
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Endocyte
Healthy
To Evaluate the PK, PD, Safety and Drug Tolerance in Healthy Volunteers
1. To evaluate the pharmacokinetic and pharmacodynamics characteristics after administration of Reference Drug or Test Drug in healthy volunteers under fasting conditions 2.
- Trial name
- NCT05433844
- Testing
- Reference Drug or Test Drug
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- JW Pharmaceutical
COVID-19
Clinical Trial to Evaluate the Safety and Immunogenicity of the COVID-19 Vaccine
This is a randomized, placebo-controlled, two center, Phase I trial in healthy adult volunteer participants consisting of two phases, an unblinded dose escalation and a double blind treatment phase to investigate the safety…
- Trial name
- COVID-19-101 (NCT04497298)
- Testing
- Two COVID-19 vaccine candidate (TMV-083/V-591) administrations - Low dose, Two COVID-19 vaccine candidate (TMV-083/V-591) administrations - High dose, One COVID-19 vaccine candidate (TMV-083/V-591) administration - High dose
- Where
- 2 sites in Belgium, France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Healthy Volunteers
A Single Dose-escalation Study to Evaluate the Safety and Pharmacokinetics of RBD1016
This is a single dose-escalation phase Ⅰa clinical study to observe the safety and pharmacokinetic profiles of RBD1016 in healthy subjects.
- Trial name
- NCT04685564
- Testing
- RBD1016
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suzhou Ribo Life Science Co. Ltd.
Healthy Male Volunteers
Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDs
drug-drug interaction between DWP14012 and three different kinds of NSAIDs
- Trial name
- NCT04490434
- Testing
- DWP14012, Celecoxib, Naproxen
- Where
- South Korea
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Frailty
A Study of Human Allogeneic Bone-marrow-derived Mesenchymal Stromal Cell Product (StromaForte) in Patients With Aging Frailty
The goal of this phase I/II clinical trial is to evaluate the safety and tolerability of intravenous infusion of human allogeneic bone-marrow-derived mesenchymal stromal cell product StromaForte in patients with aging frailty.
- Trial name
- NCT06070532
- Testing
- Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product (StromaForte)
- Where
- The Bahamas
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cellcolabs Clinical LTD.
Skin Ageing, Facial Wrinkles - Rough Texture - Hyperpigmentation
Clinical Effects of Two Oral Bioactive Collagen Peptides On Skin Properties and Aging Hallmarks
This randomized, controlled clinical trial evaluated whether daily oral intake of a collagen peptides supplement improved age-associated skin beauty parameters in healthy women with visible facial wrinkles.
- Conditions
- Skin Ageing, Facial Wrinkles - Rough Texture - Hyperpigmentation, Skin Hydration in Healthy Volunteers
- Trial name
- NCT07302789
- Testing
- Dietary Supplement: Collagen Peptides Supplement, Dietary Supplement: Competitor's Collagen Supplement
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Healthy Participants Study
Phase I Clinical Study of ZL-65 Tablet in Healthy Adult Participants in China
To evaluate the tolerability and safety of a single oral dose of ZL-65 tablets in healthy adult trial participants through dose escalation; and to preliminarily assess the pharmacokinetic and pharmacodynamic characteristics of a…
- Trial name
- NCT07757152
- Testing
- This group of participants take ZL-65 tablet
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Chengdu Zenitar Biomedical Technology Co., Ltd
Submental Fat (SMF), Double Chin
RJV001 Study in Adults Receiving Abdominoplasty
In this study, we are testing a new drug against submental fat (SMF), which is characterized with the accumulation of fat under the chin that often appears as a "double chin".
- Trial name
- NCT04821648
- Testing
- RJV001
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rejuven Dermaceutical Co., Ltd.
Pneumococcal Infections
Immunogenicity and Safety of 23-valent Pneumococcal Polysaccharide Vaccine
This is a randomized, double-blind, positive-controlled phase Ⅳ clinical trial of 23-valent pneumococcal polysaccharide vaccine manufactured by Sinovac Biotech Co., Ltd.The purpose of this study is to evaluate the immunogenicity…
- Trial name
- NCT05477693
- Testing
- Experimental 23-valent PPV, Control 23-valent PPV
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Pregnancy; Fetomaternal Hemorrhage
Clinical Efficacy of Postpartum Immunization of Rh and Coombs Negative Women With Sensitization Risk.
This a open, prospective, multicenter, single-arm, phase III study for clinical assessment of anti-Rh immunoglobulin (KamRho-D®) in Rh and Coombs negative women with risk sensitization.
- Trial name
- NCT01666249
- Testing
- Immunoglobulin Anti-RhD
- Where
- 5 sites in Brazil
- Volunteers
- 347 people, healthy volunteers welcome
- Sponsor
- Azidus Brasil
COVID-19, Vaccine Reaction
The Immunogenicity and Safety Following a Heterologous Booster Dose of Recombinant SARS-CoV-2 Vaccine LYB001
The goal of this clinical trial is to assess the immunogenicity and safety following a heterologous booster dose of recombinant SARS-CoV-2 vaccine (CHO cell) LYB001 in adults 18-59 years of age completed two- or three-dose…
- Trial name
- NCT05928455
- Testing
- LYB001, CoronaVac
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Guangzhou Patronus Biotech Co., Ltd.
Healthy Participants
Clinical Study of TS-143 in Healthy Adult Male Subjects (Single-Dose Administration)
To investigate the safety, pharmacokinetics and pharmacodynamics when administering a single dose of TS-143 to Japanese healthy adult males using a placebo-controlled, double-blind, dose-ascending study, in addition to the…
- Trial name
- NCT03591133
- Testing
- TS-143
- Where
- Japan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Co., Ltd.
Visual Acuity
Clinical Evaluation of an Investigational Lipid Drop in Non-contact Lens Wearing Patients
This is a double-masked, randomized, bilateral, 2-Arm parallel group study. Subjects are scheduled for 3 study visits (screening/baseline, 7-Day and 30-Day follow-up visits) over a period of one month.
- Trial name
- NCT03995355
- Testing
- 9618X investigational lipid eye drops, Blink® Tears
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Elevated Blood Lead Levels
Effect of Lactobacillus Plantarum DSM 33464 on Blood Lead Levels in Young Women of Child-bearing Age
We hypothesize that Lactobacillus Plantarum DSM 33464 reduce lead levels. Approximately 200 women 18 to 40 will be screened for blood lead levels.
- Trial name
- NCT05507021
- Testing
- Lactobacillus plantarum DSM 33464, MegaMetalliQ
- Where
- Mexico
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Novozymes A/S
Ametropia
Clinical Characterization of Symptomatic Populations
This is an unmasked, non-randomized, single arm, stratified, dispensing investigation of symptomatic and asymptomatic subject populations.
- Trial name
- NCT03319212
- Testing
- senofilcon A contact lenses
- Where
- 2 sites in United States, Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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