Clinical trials: Clinical
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Behavior, Child, Dentist-Patient Relations
Preparation Protocol for the First Pediatric Dental Visit
To date, not enough attention has been paid to the role of communication before the first dental visit to encourage the child's cooperation and avoid dysfunctional behaviors.
- Trial name
- PREP (NCT05608720)
- Testing
- Information Booklet
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Dandruff, Seborrhoeic Dermatitis of the Scalp
Changes in Scalp Condition After Using a Moisturizer: a Prospective Clinical Trial Using Artificial Intelligence
The goal of this clinical trial is to evaluate whether a scalp moisturizer containing celastrol and Cichorium intybus root extract can improve scalp condition in adults aged 19 years or older who require scalp moisturization due…
- Trial name
- scalp (NCT07459023)
- Testing
- Ducray Kertyol P.S.O. Concentrate Cream, Ducray Laboratory, France
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Liver Cirrhosis
A Clinical Study to Evaluate the Safety and Efficacy of Mesenchymal Stem Cells in Liver Cirrhosis
Cirrhosis is caused by sustained liver damage over several years either by alcohol, viral infection (Hepatitis B, C), a toxic substance (for eg.
- Trial name
- NCT01877759
- Testing
- Mesenchymal stem cell
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Essential Tremor
Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor
Recently, there has been increasing interest in performing DBS under general anesthesia, where the stimulated targets are located anatomically (i.e.
- Trial name
- NCT02418858
- Testing
- Deep Brain Stimulation surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
HIV Infections, Malaria
Drug Interaction Study Between Antimalarial and Anti-HIV Medications
The purpose of this study is to find out whether taking certain anti-HIV medicines with certain antimalarial medicines affects the amount of the medicines in the blood.
- Trial name
- NCT00266058
- Testing
- Lopinavir/Ritonavir, Efavirenz, Artemether/lumefantrine
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Old Age; Atrophy
Manual Ankle Therapy on Fear of Falls, Range of Motion, and Functionality and Stability in Geriatric Patients
The range of movement of the ankle decreases with age and the plantar arch decreases, adopting a more pronated position of the foot.
- Trial name
- NCT05859685
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Healthy Volunteers
Safety and Tolerability of NTX-101 in Korean Healthy Volunteers
A double-blinded, placebo controlled, multiple dose, randomized, single site, phase 1 clinical trial to evaluate safety, tolerability, and pharmacokinetics of NTX-101 topical eye drop in Korean healthy volunteers
- Trial name
- NCT05041543
- Testing
- NTX-101
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pinotbio, Inc.
HIV Infection
Clinical Trial to Reduce Drinking in Women With HIV
The primary objective of this study is to evaluate whether an intervention that involves the medication naltrexone, will reduce drinking and improve health outcomes in women with HIV infection and hazardous drinking.
- Trial name
- WHATIF (NCT01625091)
- Testing
- Naltrexone
- Where
- 2 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Florida
Denture Retention
A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive
The purpose of this study is to investigate the hold properties of two experimental denture adhesives using established maximum incisal BF methodology.
- Trial name
- NCT05173974
- Testing
- Super Poligrip Free, Experimental Denture Adhesive 1, Experimental Denture Adhesive 2
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- HALEON
Impacted Third Molar Tooth
Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
After wisdom teeth are extracted, the patient may have some complaints in the post-operative period. Pain, swelling and edema are some of them.
- Trial name
- NCT06244797
- Testing
- L-PRF and H-PRF, Impacted Tooth Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- esengul sen
Postoperative Pain
The Effect of Irrigant Types Used During Endodontic Treatment on Postoperative Pain
Chemomechanical preparation of the root canal system potentially results in extrusion of debris into the periradicular tissues. This debris is composed of hard tissue (dentin), soft tissue (inflamed or necrotic pulp tissues) and…
- Trial name
- NCT04190355
- Testing
- Irrigant type, 5.25% NaOCl, 5.25% Cloraxid gel/ distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Crestal Bone Loss
Clinical and Radiographic Evaluation of Crestal Bone Loss Around Implant With or Without Platform Switching Design
Implants have become the preferred method of single tooth replacement these days, patients receiving implant treatments not only expect restoration of masticatory function, they also expect that the prostheses will be…
- Trial name
- PS (NCT02761226)
- Testing
- Platform Matched Design (Group A), Platform Switching Design (Group B)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiopulmonary Arrest, Resuscitation
Augmented Reality to Support Cardiopulmonary Resuscitation
A prospective, multicenter, randomized clinical trial in two tertiary pediatric emergency department. It will assess, amongst pediatric healthcare teams, whether the use of augmented reality supportive devices improves adherence…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatric
- Trial name
- NCT06376643
- Testing
- Augmented reality supportive tool, Conventional method (AHA pocket reference card)
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johan Siebert, MD
Severe Combined Immunodeficiency, Atypical
Generalized Neonatal Screening of Severe Combined Immunodeficiencies
Severe combined Immunodeficiencies ( SCID ) are a group of inherited diseases of the immune system by characterised profound abnormalities of T cell development .
- Trial name
- DEPISTREC (NCT02244450)
- Testing
- SCID screening
- Where
- 51 sites in France
- Volunteers
- 190,539 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Overweight, Obesity
Mindfulness Intervention for Overweight Primary Care Patients
Mindfulness has been applied in the United States and Europe to improve both physical and psychological health, however, it is still poorly studied in Brazil.
- Trial name
- MindEat (NCT02893150)
- Testing
- TAU, TAU+MBHP, TAU+MB-EAT
- Where
- Brazil
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Centro Mente Aberta de Mindfulness
Pressure Injury, Wound
Pressure Injury Prediction and Education Model Using a Mobile Application System
Pressure injuries are common in the elderly and patients who reduced physical activities. Its complications significantly impact the health care system and social burden, even causing the death rate to be as high as 68%.
- Trial name
- NCT05357391
- Testing
- The Pressure Injury Prediction and Education model using a mobile application system
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Healthy, Prediabetic State
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile in Prediabetic and Healthy Subjects
To investigate the effect of two different dosages collagen hydrolysate (CH) on postprandial blood glucose and insulin profile in prediabetic and normo-glycaemic subjects.This will be investigated in a cross-over randomized…
- Trial name
- NCT05887791
- Testing
- Collagen hydrolysate
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Hematologic Tests
Evaluation of Potassium (K) and Ionized Calcium (iCa) Tests Using Capillary Specimens
The objective of this study is to compare the performance of blood tests using the i-STAT 1 System against a comparator blood analysis system.
- Trial name
- K iCa (NCT07287618)
- Testing
- Blood draw
- Where
- 3 sites in United States
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Abbott Point of Care
Infertility of Tubal Origin
Clinical Evaluation of a Tubal Selective Delivery System
A single center study to evaluate the performance and optimize the design of a novel intrauterine catheter system intended as a nonsignificant risk medical device to aid in evaluating tubal patency as part of the initial…
- Trial name
- NCT05775913
- Testing
- Tubal Selective Delivery System (TSDS)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
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