Clinical trials: Clinical
Infection
Infection Prevention After TKA With or Without Vancomycin
Prospective, Randomized, Double Blinded Trial Comparing Clinical, Radiological and Laboratory Outcomes in prevention of infection after Total Knee Arthroplasty With or Without Vancomycin.
- Trial name
- TKA_Vanco (NCT05461651)
- Testing
- Knee arthroplasty
- Where
- Poland
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Hypertension, Cardiovascular Diseases
Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
The purpose of the study is to increase the in vivo levels of nitric oxide by generating nitric oxide donor compound S-nitrosoacetylcysteine (SNOAC) using the mixture of sodium nitrite and N-acetylcysteine crystals in the…
- Trial name
- NCT05798481
- Testing
- Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals.
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Structured Feedback, Clinical Decision-Making, Anxiety, Self-Confidence
The Effect of Structured Feedback on Learning, Clinical Confidence and Anxiety
This research is carried out by Dr Tuba Çömez İkican, and Dr. Olga İncesu. This research aimed to determine the effect of structured written and oral feedback given to students taking psychiatric nursing course on students'…
- Conditions
- Structured Feedback, Clinical Decision-Making, Anxiety, Self-Confidence, Undergraduate Nursing Education, Learning Motivation
- Trial name
- NCT06890819
- Testing
- Assigned Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Repair
Evaluation of Air Abrasion Surface Pretreatment in the Repairing Capacity of Defective Composite Restoration
This study is conducted to compare the efficacy of surface pretreatment using air abrasion sandblasting aluminum oxide particles (Al2O3) versus not pretreatment in the repair capacity of defective composite restoration indicated…
- Trial name
- NCT05500430
- Testing
- Air abrasion sandblasting aluminum oxide particles (Al2O3) AquaCare single (Velopex, Medivance Instruments Ltd., London, UK)
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Personal Satisfaction
Clinical Evaluation of Lithium Disilicate and Hybrid Nano-ceramic Anterior Endocrowns (Randomized Clinical Trial)
the aim of this study was to evaluate the clinical performance of two CAD/CAM materials, hybrid nano-ceramic and lithium disilicate ceramic, in the fabrication of anterior endocrowns in patients with anterior endodontically…
- Trial name
- NCT04757428
- Testing
- Endocrown
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myopia, Refractive Errors
Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind Trial
This is a single-center, randomized, double-blind, controlled study to test whether a new type of eyeglass lens - a "dual-action" lens that combines two technologies (multiple defocus zones and dot diffusion) - can slow the…
- Trial name
- NCT07854457
- Testing
- Dual-Action Myopia-Control Spectacle Lens, Stellest Myopia-Control Spectacle Lens（Highly Aspherical Lenslet Target / HALT Lens）
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Influenza
Immunogenicity and Safety of Influenza Virus Vaccine, AdimFlu-S (A/H1N1), in Pediatric Population
This is a laboratory-blinded study in healthy toddlers, children, and teenagers designed to investigate the safety, reactogenicity, and immunogenicity of an inactivated influenza H1N1 vaccine (AdimFlu-S).
- Trial name
- NCT01007201
- Testing
- Influenza A (H1N1) 2009 monovalent vaccine, inactivated
- Where
- 2 sites in Taiwan
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Adimmune Corporation
Biofilms, Oils, Essential
Antiplaque Effect of Essential Oils With and Without Alcochol on an in Situ Model of Oral Biofilm Growth
The accumulation and maturation of oral biofilm in the gingival margin is widely recognised to be the primary aetiological factor in the development of chronic gingivitis.
- Conditions
- Biofilms, Oils, Essential, Periodontitis
- Trial name
- NCT02946801
- Testing
- Essential oils, Essential oils without alcohol, Sterile water
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Efficacy, Self, Satisfaction, Personal
Comparing of Using Interactive E-books and Traditional Education Methods for Nursing Students and Nursing Staff
Cancer-related comorbidities are a major focus of care for medical staff, especially the incidence of "insomnia" in cancer patients should not be underestimated, and the treatment of cancer-related insomnia by clinical medical…
- Trial name
- NCT06722001
- Testing
- The "Brief insomnia intervention" interactive e-book, traditional paper handout
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Acne Vulgaris
Venus Versa Diamondpolar Applicator Treatment Followed by AC Dual Applicator Treatment for Facial Acne Vulgaris
The purpose of the study is to evaluate the efficacy of facial acne vulgaris treatment using the Venus Versa Diamondpolar applicator in combination with the Venus Versa AC dual applicator using two intense pulsed light wavelength…
- Trial name
- NCT02924428
- Testing
- Venus Versa
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Muscles Ischemia
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty
Clinical, Biochemical and Neurophysiological Consequences of Intraoperative Tourniquet During Total Knee Arthroplasty: WOMAC-Score Knee-Score Radiographic Evaluations and Scoring System Biochemical muscle biopsy analysis
- Trial name
- NCT02475603
- Testing
- Total knee arthroplasty
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Anemia
Spot-Check Noninvasive Hemoglobin (SpHb) Clinical Validation of INVSENSOR00026
The primary objective of this clinical investigation is to evaluate the accuracy of using Masimo's INVSENSOR00026 Pulse CO-Oximeter and Sensor to measure hemoglobin, as compared to hemoglobin measurements obtained from various…
- Trial name
- NCT03610269
- Testing
- INVSENSOR00026 (Pulse CO-Oximeter and sensor)
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Healthy
Parents as Partners: Effectiveness of the Program in a Portuguese Sample
This study aims to assess the effectiveness of the "Parents as Partners" program (also named "Supporting Father Involvement"; Cowan et al., 2009) in a sample of Portuguese couples going through the transition to parenthood, i.e.…
- Trial name
- NCT06483841
- Testing
- Parents as Partners
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Ovarian Cancer
Innovative Ovarian Cancer Biomarker Assays
Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes.
- Trial name
- DISARM CSB (NCT07693894)
- Testing
- Investigational ovarian cancer biomarker assays
- Where
- 7 sites in Czechia, Greece and 3 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Late Onset Alzheimer Disease
Response to Donepezil, Drug Plasma Concentration and the CYP2D6 and APOE Genetic Polymorphisms
Pharmacological treatment of AD is currently based on cholinesterase inhibitors (ChEI) and memantine, which have been shown to lead to modest, although effective, clinical benefits.
- Trial name
- NCT03349320
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Gingival Retraction Techniques
Comparison of Two Gingival Displacement Procedures
Purpose: To compare the quality of impressions made with a cordless gingival displacement procedure versus impressions made with a corded technique.
- Trial name
- NCT02716727
- Testing
- Aquasil Ultra Cordless, Dentsply, Ultrapak, Ultradent cord
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Premature Aging
Clinical Trial to Evaluate the Addition to an Antiretroviral Treatment of a Probiotic
The main purpose of this study is to evaluate a therapy for the inflammaging (premature aging).
- Trial name
- RECOVER (NCT03542786)
- Testing
- Probiotic, Prebiotic
- Where
- Spain
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Healthy Postmenopausal Females
Bioequivalence of Nomegestrol Acetate (NOMAC) and Estradiol (E2) in Commercial Versus Phase 3 Pivotal Clinical Batches of NOMAC-E2 Tablets (P06328)
For the contraceptive application a film-coated tablet has been developed which combines nomegestrol acetate (NOMAC) with estradiol (E2).
- Trial name
- NCT01345786
- Testing
- Commercial NOMAC-E2, Phase 3 NOMAC-E2 "Batch A", Phase 3 NOMAC-E2 "Batch B"
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Diabetes, Prognosis
A Multicenter Clinical Study of Echocardiographic Assessment of Right Heart Function and Implications of Prognosis in Diabetes
The aims of this study are to 1. Evaluate the right heart structure and function in T2DM and Prediabetes patients by speckle tracking echocardiography, and to further investigate the influence of left heart on right heart…
- Trial name
- NCT04964713
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Xie Mingxing
Healthy
Effect of 12-week Probiotic Consumption Immobilized on Oat Flakes on Blood and Urine Biomarkers and Human Microbiome
The purpose of this clinical trial was to evaluate the effects Lactococcus cremoris spp. im-mobilized on oat flakes on human microbiome and blood and urine biomarkers of associated with human health.
- Trial name
- FOODBIOMES CT2 (NCT06293859)
- Testing
- Probiotic oat flakes, Conventional oat flakes
- Where
- Greece
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of the Aegean
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