Clinical trials: Clinical Anxiety
Happiness, Anxiety
Prosocial Behavior Can Safeguard Mental Health and Foster Emotional Well-being During the COVID-19 Pandemic
The COVID-19 pandemic and the accompanying lockdown measures have made mental health a pressing public health concern. Acts that focus on benefiting others-known as prosocial behaviors-offer one promising intervention that is…
- Conditions
- Happiness, Anxiety, Depression, Morality
- Trial name
- NCT04517006
- Testing
- Self-focused acts, Prosocial acts
- Where
- Canada
- Volunteers
- 1,328 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hepatobiliary Malignancy, Fluoxetine
SSRI Antidepressant Fluoxetine Improving Immunotherapy Efficacy in Advanced Hepatobiliary Malignancy Patients With Depression and Anxiety
Advanced liver and gallbladder malignancies (including liver cancer, cholangiocarcinoma and gallbladder cancer) are a type of disease that is difficult to treat, and most patients have a short survival period.
- Conditions
- Hepatobiliary Malignancy, Fluoxetine, Anxiety Disorders, Depression Disorders
- Trial name
- NCT07174947
- Testing
- Fluoxetine (drug)
- Where
- China
- Volunteers
- 240 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Non-Small Cell Lung Cancer
Clinical Effectiveness of Combining Mindfulness-Based Stress Reduction With Exercise Interventione
This study is to assess the clinical effectiveness of combining Mindfulness-Based Stress Reduction (MBSR) with exercise intervention in improving anxiety, depression, sleep quality, and mood regulation in Chinese patients with…
- Trial name
- NCT06224504
- Testing
- routine health education, psychological nursing, MBSR therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanxi Bethune Hospital
Anxiety
The Anxiety of Parents of Children Undergoing Cardiac Surgery
This is a randomized clinical trial. The population consisted of parents of children undergoing cardiac surgery from December 2010 to April 2011.
- Trial name
- NCT01492452
- Testing
- standardized guidelines for nursing
- Volunteers
- 44 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Depression, Anxiety
Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Subjects Exhibiting Neuropsychiatric Disorders
The purpose of this study is to evaluate the effect of pharmacogenetic (PGx) testing on clinical outcomes in a group of subjects exhibiting neuropsychiatric disorders, such as depression and anxiety, as compared to a group of…
- Trial name
- NCT02411123
- Testing
- IDgenetix Neuropsychiatric Test Panel
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- AltheaDx
Behavior, Dental Anxiety
Parental Affect in Dental Procedures
Background: To evaluate the effect of the anxiety of a parent accompanying a child on the child's anxiety during treatment. Methods: Parents of 160 patients (4-8 years old) were divided into two groups anxious and non-anxious.
- Trial name
- NCT04636580
- Testing
- parent accompanying the child during treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Uşak University
Gingival Health, Space Maintenance
the Objective of This Research is to Compare the Clinical Effectiveness of the Conventional Lingual Arch Space Maintainers With Three-dimensional Printed Space Maintainers.
the objective of this research is to compare the clinical effectiveness of the conventional lingual arch space maintainers with three-dimensional printed space maintainers.
- Conditions
- Gingival Health, Space Maintenance, Pain and Anxiety
- Trial name
- NCT07591324
- Testing
- Conventional spacemaintainer, 3D printed spacemaintainer
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Suez Canal University
Pain, Local Infiltration
Pain Perception With a Comfort-ın Jet Injection and Conventional Dental Injection
The investigators aimed to compare the effectiveness of the Comfort-in system, which is a jet injection type, and infiltrative anesthesia with a traditional injector, and to measure the effect of children's anxiety on the…
- Conditions
- Pain, Local Infiltration, Anesthesia, Fear
- Trial name
- NCT04682080
- Testing
- Needle-free injection
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Alcohol Abuse, Anxiety
Personalized Feedback Intervention for Latinx Drinkers With Anxiety
The purpose of this study is to develop, evaluate the acceptability/feasibility (Phase IA), and test (Phase IB) the effectiveness of a brief, integrated, single-session, computer-based, culturally adapted personalized feedback…
- Trial name
- NCT05246202
- Testing
- Alcohol-Anxiety Personalized Feedback Intervention 2.0, Control Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Houston
Cognitive Therapy, Depression, Postpartum
RCT of Automated Conversational Agent vs. Treatment as Usual for the Management of Perinatal Mood
The purpose of this study is to investigate the efficacy of an evidence-based smartphone application (app) for the management of mood compared to treatment as usual alone among 135 women who have been discharged post-delivery…
- Conditions
- Cognitive Therapy, Depression, Postpartum, Mental Health, Depression
- Trial name
- NCT03646539
- Testing
- Use of smartphone application (app), Treatment as usual
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Stanford University
Social Anxiety Disorder, Social Fear
Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)Therapy for Social Anxiety Disorder
This clinical trial aims to evaluate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) in patients with social anxiety disorder (SAD).
- Trial name
- taVNS (NCT07772401)
- Testing
- taVNS
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pediatric Medication
The Effect of the Virtual Escape Room Method on Pediatric Drug Administration Knowledge, Self-Efficacy, Clinical Comfort, and Anxiety in Nursing Students: A Randomized Controlled Study
Children are particularly vulnerable to injuries resulting from medication errors due to the severity of the illness, the need for high-risk drugs with a narrow therapeutic range, and the frequent use of intravenous infusions.
- Trial name
- Pediatric Drug (NCT06981403)
- Testing
- virtual escape room game-based pediatric medication management education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Malocclusion, Pain
Anxiety, Pain, and Quality of Life in Orthodontic Treatment
This study was evaluated anxiety, pain, and oral health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase…
- Conditions
- Malocclusion, Pain, Anxiety, Quality of Life
- Trial name
- NCT06133296
- Testing
- Conventional fixed treatment, Clear aligner treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Parkinson's Disease, Generalized Anxiety Disorder
Cognitive Behavioural Therapy for Anxiety Disorders in PD
Anxiety disorders occur in up to 35% of patients with Parkinson's disease (PD) and have a negative effect on gait, dyskinesia, freezing, on/off fluctuations, and quality of life.
- Conditions
- Parkinson's Disease, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT02648737
- Testing
- Cognitive Behavioural Therapy (CBT), Clinical monitoring
- Where
- 2 sites in France, Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Phobias
Fear of Childbirth (Tokophobia) - Etiology, Essence and Clinical Implications
The purpose of this study is twofold: to understand the etiology and the essence of fear of childbirth to examine the implications and efficiency of several forms of psychological therapy.
- Trial name
- NCT00801970
- Testing
- Psychological Treatment, Group Therapy
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Low Back Pain, Mechanical, Chronic Pain
The Long Term Effects of Online Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain
This study aims to evaluate the effects of online Therapeutic Neuroscience Education (TNE) combined with a 6-week conventional physiotherapy program on pain, disability, kinesiophobia, functionality, treatment expectations, and…
- Trial name
- NCT06847763
- Testing
- Therapeutic Neuroscience Education, Conventional Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Stress, Anxiety
Effects of an Osteopathic Manual Therapy Protocol on Heart Rate Variability, Stress, and Anxiety in Young Adults
Anxiety is characterized by excessive worry and anticipation of future threats, often accompanied by physiological and behavioral manifestations.
- Trial name
- NCT07670806
- Testing
- Fourth Ventricle Technique, Suboccipital Decompression, Diaphragm Myofascial Release Technique
- Where
- Portugal
- Volunteers
- 30 people
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Healthy Volunteers
Safety, Tolerability, and Efficacy of Sublingual Microdoses of 5-MeO-DMT for Depression and Anxiety
This Phase I/II clinical trial investigates the safety, tolerability, and potential therapeutic benefits of a novel sublingual formulation of 5-MeO-DMT.
- Trial name
- 5-MeO-DMT (NCT06816667)
- Testing
- BMND08, Brain electrical activity monitor, Pharmacokinetic Study of Sublingually Administered Psychoactive Substance
- Where
- Argentina
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biomind Labs Inc.
Postoperative Pain
Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial
This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery.
- Trial name
- NCT07413055
- Testing
- Dexamethasone 4 Mg/mL Injectable Solution, Dexamethasone 8Mg Solution for Injection
- Where
- Oman
- Volunteers
- 138 people
- Sponsor
- Oman Ministry of Health
Dental Anxiety, Pain
Dental Anxiety and Pain During Inferior Alveolar Nerve Block in Children: the Effects of Two Distraction Techniques
Objectives: To compare the effectiveness of virtual reality (VR) and external cooling and vibration distraction techniques on dental anxiety and pain in children during inferior alveolar nerve block (IANB).
- Conditions
- Dental Anxiety, Pain, Distraction Methods, Local Anesthesia
- Trial name
- NCT06788301
- Testing
- Inferior Alveolar Nerve Block, VR eyeglasses, Buzzy device
- Where
- Turkey (Türkiye)
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Pamukkale University