Clinical trials: Clinical Outcomes
Gingival Recession, Lack of Keratinized Gingiva
A Comparison of Side Access Mucosal Releasing Incision (SAMRI) and Sulcular Tunnel Access to Treat Gingival Recession.
This study will compare two incision designs to allow for coronal gingival/mucosal flap advancement and tissue augmentation with acellular dermal matrix (ADM) graft around teeth with gingival recession and a lack of adequate…
- Trial name
- NCT04179448
- Testing
- SAMRI, STA
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Periodontal Diseases, Periodontitis (Stage 3)
Influence of Re-evaluation Timing After Phase I Periodontal Therapy on Clinical and Periodontal Outcomes.
Periodontal disease remains a highly prevalent chronic inflammatory condition affecting the supporting structures of the teeth and is a leading cause of tooth loss worldwide.
- Conditions
- Periodontal Diseases, Periodontitis (Stage 3), Subgingival Debridement
- Trial name
- NCT07678125
- Testing
- Early follow up, Delayed follow up
- Where
- United Arab Emirates
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Missing Teeth
Different Surgical Drilling Protocols in Posterior Maxilla
Sixteen dental implants inserted in sixteen patients who were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University, for the rehabilitation of missed…
- Trial name
- NCT06334081
- Testing
- undersized drilling technique, single drilling technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cerebral Small Vessel Diseases, Cadasil
Taiwan Associated Genetic and Nongenetic Small Vessel Disease
The TAG-SVD enrolled patients with clinical and neuroimaging features of cerebral small vessel disease (CSVD). All enrolled patients will receive next-generation sequence (NGS) with probes designed to target five candidate CSVD…
- Conditions
- Cerebral Small Vessel Diseases, Cadasil, HTRA1-Related Autosomal Dominant Cerebral Angiopathy, COL4A1-Related Brain Small Vessel Disease With Haemorrhage
- Trial name
- TAG-SVD (NCT05473637)
- Testing
- MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Contraceptive Usage
Clinical Use of a Contraceptive Decision Aid and Patient Outcomes
The study at hand aims to examine whether incorporating use of a contraceptive decision aid (Tuune for Clinics) improves outcomes for patients seeking contraceptive care.
- Trial name
- NCT05973071
- Testing
- Tuune Supplemented Contraceptive Visit, Traditional Contraceptive Visit
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Periodontitis With Low Oral Hygiene-related Self-efficacy
Evaluation of Behaviour Intervention on Adherence and Periodontal Outcomes
Periodontitis is a chronic inflammatory disease in which long-term treatment success depends greatly on patients' adherence to oral hygiene practices and periodontal therapy.
- Trial name
- NCT07614737
- Testing
- Behavioural intervention, Conventional oral hygiene instructions
- Where
- India
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Visual Outcomes
Comparison of Clinical Outcomes in Ziemer Femtosecond Versus Conventional Phacoemulsification Surgery
This study is aimed to compare the clinical outcomes in Ziemer LDV Z8 femtosecond laser-assisted cataract surgery versus conventional phacoemulsification cataract surgery
- Trial name
- NCT03351894
- Testing
- Femtosecond laser assisted cataract surgery, Conventional phacoemulsification
- Where
- Singapore
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Singapore Eye Research Institute
Advanced Cardiac Life Support Education
Effects of Two-Tier Test-Based Virtual Reality Instruction on ACLS Outcomes Among Clinical Nurses
This study aims to evaluate the effects of two-tier test-based virtual reality (VR) instruction on Advanced Cardiac Life Support (ACLS) learning outcomes among clinical nurses.
- Trial name
- NCT07862322
- Testing
- Two-Tier Test-Based Virtual Reality Instruction, Traditional Interactive Virtual Reality Instruction
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taoyuan General Hospital
Nursing Students, Artificial Intelligence (AI)
AI-Supported Case Analysis Among Nursing Students
The aim of this study is to determine the effect of AI-supported internal medicine nursing case analysis on students' case management performance, learning outcomes, learning experience, clinical self-efficacy, and cognitive load…
- Trial name
- NCT07614503
- Testing
- Case Analysis, AI-supported case
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Gingivitis, Pregnancy
Oral Hygiene and Maternity Outcomes Multicenter Study (OHMOM)
This study will track changes in oral health in pregnant women. Subjects will be assigned to either regular oral care or advanced oral care and be given oral care products to use until they deliver.
- Trial name
- OHMOM (NCT01549587)
- Testing
- 0.243% sodium fluoride, toothbrush, dental floss
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Alzheimer Disease
Pre-Clinical (Alzheimers) Diagnosis PCD = Optimum Outcomes OO
This Observational protocol will attempt to verify two recent and very critical concepts in ALZ Clinical Research by studying high-risk individuals who already are taking medications which may prevent the onset of ALZ.
- Trial name
- PCD=OOALZ (NCT02835716)
- Testing
- roflumilast, ustekinumab
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Millennium Magnetic Technologies, LLC
Aesthetic
PLLA and CaHA-R for Aesthetic Rejuvenation
Skin ageing is intricately linked to collagen degradation caused by internal and external factors. External factors contributing to ageing include ultraviolet rays, smoking, heat, and air pollution, and follow a distribution…
- Trial name
- NCT07202117
- Testing
- Sculptra Aesthetic, Radiesse
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Third Molar Surgery, Postoperative Complications
Effect of Irrigation Solution Temperature on Clinical Outcomes and Salivary CRP After Impacted Mandibular Third Molar Surgery
Surgical extraction of impacted mandibular third molars often requires bone removal using rotary instruments, in which friction between the bur and bone generates heat.
- Conditions
- Third Molar Surgery, Postoperative Complications, C-REACTIVE PROTEIN
- Trial name
- NCT07243210
- Testing
- Cold Saline Irrigation, Room-Temperature Saline Irrigation (Control)
- Where
- Vietnam
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pregnancy in Diabetes, Pregnancy
Are There Any Clinical Benefits to Screening for Late -Onset Gestational Diabetes Mellitus?"
This study aims to screen women who have a negative Gestational diabetes mellitus (GDM) result in routine screening tests or who have never had it with the Fasting Blood Glucose Test (FBG) at 32-34 weeks of gestation to diagnose…
- Conditions
- Pregnancy in Diabetes, Pregnancy, Pregnancy Outcomes
- Trial name
- NCT07776314
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Heart Failure, Diffuse Fibrosis
Using Cardiovascular Magnetic Resonance Tissue Characterisation and Wearable Technology to PREDICT Clinical Outcomes, Response to Therapy and Arrhythmias in Hospitalised Heart Failure Patients
150 patients admitted to University Hospital Southampton with heart failure will undergo comprehensive Cardiovascular Magnetic Resonance (CMR) imagining during their admission and continuous heart rhythm monitoring using wearable…
- Conditions
- Heart Failure, Diffuse Fibrosis, Focal Fibrosis, Arrythmia
- Trial name
- PREDICT-HF (NCT03689426)
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Gynecologic Disease
Fast-track in Minimally Invasive Gynaecology
Objective: Evaluate the effects of a fast-track (FT) protocol on costs and postoperative recovery. Design: randomized trial Setting: University Hospitals Population: 170 women undergoing total laparoscopic hysterectomy for a…
- Trial name
- NCT04839263
- Testing
- "FAST TRACK" protocol
- Where
- 2 sites in Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Patellofemoral Pain
Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain
The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.
- Trial name
- NCT05285007
- Testing
- Mobilization with Movement, No mobilization with movement and education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Root Caries, Vertical Root Fracture
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07633834
- Testing
- hemi sectioning
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
IVF
Non-Invasive Preimplantation Genetic Screening for Aneuploidies and Clinical Outcomes in Egg Donation Patients
Preimplantation genetic testing for aneuploidies (PGT-A) is commonly used in IVF but requires embryo biopsy and shows limited benefit in egg donation cycles.
- Trial name
- niPGTAdon (NCT07364526)
- Where
- Spain
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Dental Caries
Biodentine Pulpotomy vs Metapex Pulpectomy in Primary Molars: Clinical & Radiographic Comparison of Outcomes in Irreversible Pulpitis Cases
Irreversible pulpitis is defined as a clinical diagnostic based on subjective and objective findings suggesting that the vital inflamed pulp is incapable of healing in the American Association of Endodontists (AAE) Consensus…
- Trial name
- NCT06524921
- Testing
- dental pulpectomy using metapex, dental pulpotomy using biodentine
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Mohamed Ahmed Hamdi Abo El Yamin