Clinical trials: Clinical Pain
Chronic Apical Periodontitis
Single Versus Multiple Visits Regenerative Endodontics in Mature Teeth
The goal of this clinical trial is to learn whether regenerative endodontic treatment (RET) should be performed in one visit or two visits in people with mature permanent teeth with chronic apical periodontitis.
- Trial name
- NCT07480226
- Testing
- Single-Visit Regenerative Endodontic Treatment, Multiple-Visit Regenerative Endodontic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Marmara University
Pain, Acute
Optimal Timing of Parasternal Intercostal Nerve Block Application for Acute Pain Management in Cardiac Surgery
Patients experiencing pain after undergoing cardiac surgery may also experience prolonged immobilization, insufficient respiratory functions, and the inability to cough due to median sternotomy.
- Trial name
- NCT05363540
- Testing
- pre-incisional parasternal intercostal block, post-incisional parasternal intercostal block
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Benha University
Blood Pressure
Fibromyalgia and Circadian Blood Pressure
Fibromyalgia syndrome (FMS) is a chronic and multicomponent illness with unknown etiology and is considered the most frequent cause of diffuse chronic musculoskeletal pain.
- Trial name
- NCT05113589
- Testing
- PBM TREATMENT
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Malaga
Upper Trapezius Trigger Points
Effects of IC With and Without MET on Upper Trapezius Trigger Points
the aim of the study is to check the effects of ischemic compression with and without muscle energy technique on Pain, Range of motion, and Functional Disability on myofascial trigger points in the upper trapezius.
- Trial name
- NCT05415813
- Testing
- Ischemic Compression, Ischemic compression with Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Lahore
Fracture
Cannabidiol After Multi-Trauma for Pain and Opioid Therapy
The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex…
- Trial name
- CAM-POT (NCT06448923)
- Testing
- Cannabidiol
- Where
- Canada
- Volunteers
- 225 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Chest Pain, Dyspnea
ER-VISION-AI Study
Prospective, multicenter, randomized, open-label, blinded-endpoint (PROBE-like) clinical trial evaluating whether physician-supervised Generative Pre-trained Transformer (GPT)-assisted multimodal diagnostic support improves…
- Conditions
- Chest Pain, Dyspnea, Acute Cardiopulmonary Disease, Emergency Department Patients
- Trial name
- ER-VISION-AI (NCT07727590)
- Testing
- Generative Pre-trained Transformer (GPT)-assisted multimodal visual language model (VLM) diagnostic support, Conventional emergency department diagnostic evaluation
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Stable Angina Pectoris
Evaluation and Comparison of Several Point-of-care Platelet Function Tests in Predicting Clinical Outcomes in Clopidogrel Pre-treated Patients Undergoing Elective PCI.
The purpose of this study is to investigate whether the level of Platelet Inhibition as assessed with five point-of-care platelet function assays correlates with clinical (periprocedural) outcomes such as Acute Myocardial…
- Trial name
- NCT00352014
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- R&D Cardiologie
Obstetric Pain, Labor Pain
Dural Puncture Epidural VS Standard Epidural on Physician Top-ups During Labour Analgesia
The purpose of this prospective randomized controlled study is to compare the number of physician top-up interventions during the first stage of labour between two different neuraxial analgesia techniques : the dural puncture…
- Conditions
- Obstetric Pain, Labor Pain, Anesthesia
- Trial name
- DPE (NCT04728048)
- Testing
- Dural puncture epidural, Standard epidural
- Where
- Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Acne Vulgaris
Reduced Side-Effects of Photodynamic Therapy for the Treatment of Moderate to Severe Acne (i-PDT)
This research study aims to compare different methods for helping difficult to treat or scarring (cystic) acne, ALA-PDT and i-PDT.
- Trial name
- i-PDT (NCT01689935)
- Testing
- 20 % Aminolevulinic Acid, Red light only, Blue light only
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy
Foot Manipulation for Pregnancy Related Pelvic Girdle Pain
Background: Asymmetrical foot posture influences the pelvic girdle stability and might give pain in the pelvic region. The objective was to investigate if foot manipulation to correct foot asymmetry can relieve pregnancy related…
- Trial name
- PPGP (NCT01894009)
- Testing
- Foot manipulation
- Where
- Sweden
- Volunteers
- 97 people
- Sponsor
- Vastra Gotaland Region
Carpal Tunnel, Carpal Tunnel Syndrome
Efficacy of Electroacupuncture in Carpal Tunnel Syndrome
The aim of this clinical study is to assess the effectiveness of electroacupuncture in reducing the severity of symptoms, in improving limb function, in improving the aesthetic and motor conduction of the median nerve and in…
- Conditions
- Carpal Tunnel, Carpal Tunnel Syndrome, Pain, Pain Syndrome
- Trial name
- NCT04603274
- Testing
- 8 sessions of electroacupuncture to the upper limb with carpal tunnel syndrome
- Where
- 2 sites in Greece
- Volunteers
- 25 people
- Sponsor
- Aretaieion University Hospital
Infertility, Female
Clinical Efficacy of Virtual Reality During Office Hysteroscopy and Endometrial Biopsy in Subfertility
This study is a comparison between the current standard practice of performing a diagnostic hysteroscopy and a relatively recently developed technology that is added to the standard diagnostic hysteroscopy.
- Trial name
- HYSVIR (NCT04438759)
- Testing
- Oncomfort, commercially available Virtual Reality headset
- Where
- Belgium
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Neuralgia, Spinal Cord Injury
Symptom Based Treatment of Neuropathic Pain
1. Neuropathic pain in spinal cord injured patients 1. Inclusion criteria pain intensity, visual analogue scale > 3 a LANSS (Leeds assessment of neuropathic symptoms and signs) score of 12 and above aged ≥20 2.
- Trial name
- NCT02180880
- Testing
- Pregabalin and Oxcarbazepine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Ju Seok Ryu
Malocclusion, Pain
Anxiety, Pain, and Quality of Life in Orthodontic Treatment
This study was evaluated anxiety, pain, and oral health-related quality of life in individuals treated with conventional fixed appliances (Group A) and clear aligners (Group B) for moderate malocclusion during the initial phase…
- Conditions
- Malocclusion, Pain, Anxiety, Quality of Life
- Trial name
- NCT06133296
- Testing
- Conventional fixed treatment, Clear aligner treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain, Postoperative
Preemptive Analgesia With Amitryptyline for Prevention of Pain in Women After Hysterectomy
The purpose of this study is to determine whether amitryptyline is effective in the prevention of pain in women after a total abdominal hysterectomy.
- Trial name
- NCT03587025
- Testing
- Amitriptyline
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil
Pulmonary Embolism, Dyspnea
PERCEPIC: PERC Rule Combined With Implicit Low Clinical Probability
PERC rule was created to rule out pulmonary embolism (PE) without further exams, with residual PE risk <2%. Its safety is currently confirmed in low PE prevalence populations as north-American.
- Conditions
- Pulmonary Embolism, Dyspnea, Thoracic Pain
- Trial name
- PERCEPIC (NCT02360540)
- Testing
- Gestalt estimation
- Where
- 12 sites in Belgium, France
- Volunteers
- 1,773 people
- Sponsor
- University Hospital, Angers
Shoulder Impingement Syndrome
Randomized Clinical Trial of Rehabilitation for Subacromial Impingement Syndrome
The purpose of this randomized double-blind clinical trial is to determine the effectiveness of manual therapy for patients with subacromial impingement syndrome of the shoulder.
- Trial name
- NCT00633451
- Testing
- Manual Therapy and Exercise, Exercise Only
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Proaxis Therapy
Coronary Artery Disease With Myocardial Infarction
Pragmatic Trial Comparing Symptom-Oriented Versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention
The primary objective of the POST-PCI trial is to compare the clinical outcomes of a post-percutaneous coronary intervention(PCI) aggressive management strategy of routine noninvasive functional testing to a usual-care strategy…
- Trial name
- POST PCI (NCT03217877)
- Testing
- routine stress testing, No Routine stress testing
- Where
- 11 sites in South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seung-Jung Park
Symptomatic Irreversible Pulpitis
Comparison of Post-Operative Pain Occurrence After Single Visit Root Canal Treatment
The goal of this clinical trial is to compare the post-operative pain occurrence after single visit root canal treatment using Two NiTi Rotary Files.
- Trial name
- NCT06777381
- Testing
- single visit root canal treatment using ProTaper Universal rotary system, single visit root canal treatment using M-Pro rotary system
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- National Research Centre, Egypt
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